近期论文

Rothnie A., Clarke A.R., Kuzmic P., Cameron A. & Smith C.J. (2011) A sequential mechanism for clathrin cage disassembly by Hsc70 and auxilin.Proc. Natl. Acad. Sci USA108; 6927-32
Maeno K., Nakajima A., Conseil G., Rothnie A., Deeley R.G. & Cole S.P.C (2009) Molecular basis for reduced estrone sulphate transport & altered modulator sensitivity of TM6 and TM17 mutants of MRP1 (ABCC1). Drug Metab. & Dispos. 37; 1411-20.
Conseil G., Rothnie A., Deeley R.G. & Cole S.P.C. (2009). Multiple roles of charged amino acids in cytoplasmic loop 7 for the expression and function of the multidrug and organic anion transporter MRP1 (ABCC1). Mol. Pharmacol. 75; 397-406.
Heikal A., Box K., Rothnie A., Storm J., Callaghan R. & Allen M. (2009) The stabilisation of purified, reconstituted, P-glycoprotein by freeze drying with disaccharides. Cryobiology 58; 37-44.
Rothnie A., Conseil G., Lau A.Y.T., Deeley R.G. & Cole S.P.C. (2008) Mechanistic differences between GSH transport by MRP1 (ABCC1) and GSH modulation of MRP1-mediated transport. Mol. Pharmacol. 74; 1630-40.
Rothnie A., Callaghan R., Deeley R.G. & Cole S.P.C. (2006). Role of GSH in estrone sulphate binding and translocation by the multidrug resistance protein 1 (MRP1, ABCC1). J. Biol. Chem. 281; 13906-14.
Rothnie A., Storm J., McMahon R., Taylor A., Kerr I.D. & Callaghan R. (2005). The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment. FEBS Letts. 579; 3984-90.
Rothnie A., Storm J., Campbell J., Linton K.J., Kerr I.D. & Callaghan R. (2004). The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein. J. Biol. Chem. 279; 34913-21.
Martin C., Walker J., Rothnie A. & Callaghan R. (2003). The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models. Brit. J. Cancer 89; 1581-9.
Gabriel M.P., Storm J., Rothnie A., Taylor A.M., Linton K.J., Kerr I.D. & Callaghan R. (2003). Communication between the nucleotide binding domains of P-glycoprotein occurs via conformational changes that involve residue 508. Biochemistry 42; 7780-9.
Rothnie A., Theron D., Soceneantu L., Martin C., Traikia M., Berridge G., Higgins C.F., Devaux P.P. & Callaghan R. (2001). The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence. Eur. Biophys. J. 30; 30-42.