近期论文

Van Horn WD. VKORC1 ER mislocalization causes rare disease. Blood. 2014 Aug 21;124(8):1215-16. doi: 10.1182/blood-2014-07-586032. PubMed PMID: 25147380; PubMed Central PMCID: PMC4141510r
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Peng D, Kim JH, Kroncke BM, Law CL, Xia Y, Droege KD, Van Horn WD, Vanoye CG, Sanders CR. Purification and Structural Study of the Voltage-Sensor Domain of the Human KCNQ1 Potassium Ion Channel. Biochemistry. 2014 Apr 1;53(12):2032-42. doi:10.1021/bi500102w. PubMed PMID: 24606221; PubMed Central PMCID: PMC3977583.r
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Van Horn WD. Structural and functional insights into human vitamin K epoxide reductase and vitamin K epoxide reductase-like 1. Crit. Rev. Biochem. Mol. Biol. 2013. Jul-Aug;48(4):357-72. doi:10.3109/10409238.2013.791659. Epub 2013 Apr 30.r
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Barrett PJ, Chen J, Cho MK, Kim JH, Lu Z, Mathew S, Peng D, Song Y, Van Horn WD, Zhuang T, Sönnichsen FD, Sanders CR. The quiet renaissance of protein nuclear magnetic resonance. Biochemistry. 2013 Feb 26;52(8):1303-20. doi: 10.1021/bi4000436. Epub 2013 Feb 12. PubMed PMID: 23368985; PubMed Central PMCID: PMC3592982.r
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Shi M, Pedchenko V, Greer BH, Van Horn WD., Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A. Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis. J Biol Chem. 2012 Oct 12;287(42):35139-52. doi: 10.1074/jbc.M112.358648. Epub 2012 Aug 10. PubMed PMID: 22888006; PubMed Central PMCID: PMC3471707.r
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Barrett PJ, Song Y, Van Horn WD, Hustedt EJ, Schafer JM, Hadziselimovic A, Beel AJ, Sanders CR. The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Science. 2012 Jun 1;336(6085):1168-71. doi: 10.1126/science.1219988. PubMed PMID: 22654059; PubMed Central PMCID: PMC3528355.r
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Lu Z, Van Horn WD, Chen J, Mathew S, Zent R, Sanders CR. Bicelles at low concentrations. Mol Pharm. 2012 Apr 2;9(4):752-61. doi: 10.1021/mp2004687. Epub 2012 Jan 20. PubMed PMID: 22221179; PubMed Central PMCID: PMC3319193.r
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Van Horn WD, Sanders CR. Prokaryotic diacylglycerol kinase and undecaprenol kinase. Annu Rev Biophys. 2012;41:81-101. doi: 10.1146/annurev-biophys-050511-102330. Epub 2011 Dec 20. PubMed PMID: 22224599.r
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Van Horn WD, Vanoye CG, Sanders CR. Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel. Curr Opin Struct Biol. 2011 Apr;21(2):283-91. doi: 10.1016/j.sbi.2011.01.001. Epub 2011 Feb 4. Review. PubMed PMID: 21296569; PubMed Central PMCID: PMC3070781.r
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Kang C, Vanoye CG, Welch RC, Van Horn WD, Sanders CR. Functional delivery of a membrane protein into oocyte membranes using bicelles. Biochemistry. 2010 Feb 2;49(4):653-5. doi: 10.1021/bi902155t. PubMed PMID: 20044833; PubMed Central PMCID: PMC2811756.r
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Van Horn WD, Beel AJ, Kang C, Sanders CR. The impact of window functions on NMR-based paramagnetic relaxation enhancement measurements in membrane proteins. Biochim Biophys Acta. 2010 Feb;1798(2):140-9. doi: 10.1016/j.bbamem.2009.08.022. Epub 2009 Sep 12. PubMed PMID: 19751702; PubMed Central PMCID: PMC2812639.r
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Kim HJ, Howell SC, Van Horn WD, Jeon YH, Sanders CR. Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Prog Nucl Magn Reson Spectrosc. 2009 Nov 1;55(4):335-360. PubMed PMID: 20161395; PubMed Central PMCID: PMC2782866.r
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Van Horn WD, Kim HJ, Ellis CD, Hadziselimovic A, Sulistijo ES, Karra MD, Tian C, Sönnichsen FD, Sanders CR. Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase. Science. 2009 Jun 26;324(5935):1726-9. doi: 10.1126/science.1171716. PubMed PMID: 19556511; PubMed Central PMCID: PMC2764269.r
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Van Horn WD, Ogilvie ME, Flynn PF. Reverse micelle encapsulation as a model for intracellular crowding. J Am Chem Soc. 2009 Jun 17;131(23):8030-9. doi: 10.1021/ja901871n. PubMed PMID: 19469539.r
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Van Horn WD, Ogilvie ME, Flynn PF. Use of reverse micelles in membrane protein structural biology. J Biomol NMR. 2008 Mar;40(3):203-11. doi: 10.1007/s10858-008-9227-5. Epub 2008 Feb 23. PubMed PMID: 18297402.r
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Flynn PF, Simorellis AK; Van Horn W D. NMR Studies of encapsulated proteins. Annu. Reports NMR Spectroscopy. 2007; 62:179-219. doi: 10.1016/S0066-4103(07)62004-3.r
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Simorellis AK, Van Horn WD, Flynn PF. Dynamics of low temperature induced water shedding from AOT reverse micelles. J Am Chem Soc. 2006 Apr 19;128(15):5082-90. PubMed PMID: 16608342.
Van Horn WD, Simorellis AK, Flynn PF. Low-temperature studies of encapsulated proteins. J Am Chem Soc. 2005 Oct 5;127(39):13553-60. PubMed PMID: 16190719.