个人简历

研究领域

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近期论文

1． Xiaohua Yu#, Yong Zhang#*, Tingting Li, Zhao Ma, Haixue Jia, Qian Chen, Yixia Zhao, Lili Zhai, Ran Zhong, Changyin Li, Xiaoting Zou, Jiao Meng, Antony K. Chen, Pier Lorenzo Puri, Meihong Chen, and Dahai Zhu*. Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD. Nat Commun. 2017. Jan 16;8:14016.\r
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2． Lili Zhai, Rimao Wu, Wanhong Han, Yong Zhang* and Dahai Zhu*. miR-127 promotes myogenic cell differentiation by targeting S1PR3. Cell Death Dis. 2017. Mar 30;8(3):e2707. doi: 10.1038/cddis.2017.128.\r
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3． Haixue Jia#, Yixia Zhao#, Tingting Li, Yong Zhang*, Dahai Zhu*. miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fiber-type composition. Acta Biochim Biophys Sin. 2017. Mar 17:1-8. doi: 10.1093/abbs/gmx019. [Epub ahead of print]\r
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4． Yue Fan, Ying Zhang, Rimao Wu, Xingming Chen, Yong Zhang*, Xiaowei Chen*, Dahai Zhu. miR-431 is involved in regulating cochlear function by targeting Eya4. BBA - Molecular Basis of Disease. 2016 Nov;1862(11):2119-2126. doi: 10.1016/j.bbadis.2016.08.015. Epub 2016 Aug 19.\r
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5． Ping Zeng, Wanhong Han, Changyin Li, Hu Li, Dahai Zhu, Yong Zhang*, Xiaohong Liu*. miR-378 attenuates muscle regeneration by delaying satellite cell activation and differentiation in mice. Acta Biochim Biophys Sin. 2016 Sep;48(9):833-9. doi: 10.1093/abbs/gmw077. Epub 2016 Aug 25. \r
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6． Yong Zhang, Changyin Li, Hu Li, Yipeng Song, Yixia Zhao, Lili Zhai, Haixia Wang, Ran Zhong, Huiru Tang, and Dahai Zhu*. miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice. EBioMedicine. 2016. Mar 11;5:93-104.\r
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7． Xiaoting Zou, Jiao Meng, Li Li, Wanhong Han, Changyin Li, Ran Zhong, Xuexia Miao, Jun Cai, Yong Zhang* and Dahai Zhu*. Acetoacetate accelerates muscle regeneration and ameliorates muscular dystrophy in mice. J Biol Chem. 2016 Jan 29;291(5):2181-95. Epub 2015 Dec 8.\r
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8． Rimao Wu, Hu Li, Lili Zhai, Xiaoting Zou, Jiao Meng, Ran Zhong, Changyin Li, Haixia Wang, Yong Zhang*, Dahai Zhu*. MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nat Commun. 2015 Jul 7;6:7713. doi: 10.1038/ncomms8713.\r
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9． He Cheng, Audi Wang, Jiao Meng, Yong Zhang, Dahai Zhu*. Enhanced metastasis in RNF13 knockout mice is mediated by a reduction in GM-CSF levels. Protein & Cell, 2015 Oct;6(10):746-56.\r
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10． Rimao Wu, Hu Li, Tingting Li, Yong Zhang*, Dahai Zhu*. Myostatin regulates miR-431 expression via the Ras-Mek-Erk signaling pathway. Biochem Biophys Res Commun. 2015 May 29;461(2):224-9. doi: 10.1016/j.bbrc.2015.03.150. Epub 2015 Apr 11.\r
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11．Jiao Meng, Xiaoting Zou, Rimao Wu, Ran Zhong, Dahai Zhu* and Yong Zhang*. Accelerated Regeneration of Skeletal Muscle in RNF13-Knockout Mice is Mediated by Macrophage-Secreted IL-4/IL-6. Protein & Cell, 2014 Mar;5(3):235-247.\r
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12． Yong Liu, He Cheng, Yuchang Zhou, Yushan Zhu, Rui Bian, Yuewen Chen, Changyin Li, Qi Ma, Qiaoxia Zheng, Yong Zhang, Haijing Jin, Xiaohui Wang, Quan Chen, Dahai Zhu*. Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells. Cell Death Dis. 2013 Feb 14;4:e494.\r
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13． Qiang Zhang, Yanfeng Li, Lei Zhang, Nan Yang, Jiao Meng, Pingping Zuo, Yong Zhang, Jie Chen, Li Wang, Xiang Gao, Dahai Zhu*. E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex. Cell Mol Life Sci. 2013 Jan;70(1):153-65. Epub 2012 Aug 14\r
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14． Yao Song, Jialin Xu, Yanfeng Li, Chunshi Jia, Xiaowei Ma, Lei Zhang, Xiaojie Xie, Yong Zhang, Xiang Gao, Youyi Zhang, Dahai Zhu*. Cardiac Ankyrin Repeat Protein Attenuates Cardiac Hypertrophy by Inhibition of ERK1/2 and TGF-b Signaling Pathways. PLoS One. 2012;7(12):e50436. Epub 2012 Dec 5. \r
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15． Tingting Li, Suya Wang, Rimao Wu, Xueya Zhou, Dahai Zhu*, Yong Zhang*. Identification of long non-protein coding RNAs in chicken skeletal muscle using next generation sequencing. Genomics, 2012 May;99(5):292-8. Epub 2012 Feb 20.\r
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16． Tingting Li, Rimao Wu, Yong Zhang, Dahai Zhu*. A systematic analysis of the skeletal muscle miRNA transcriptome of chicken varieties with divergent skeletal muscle growth identifies novel miRNAs and differentially expressed miRNAs. BMC Genomics. 2011 Apr 13;12(1):186.\r
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17． Li Wang, Xiao-Pan Wu, Wei Zhang, Dahai Zhu, Ying Wang, Yan-Ping Li, Yao Tian, Rong-Cheng Li, Zhuo Li, Xinlin Zhu, Jun-Hong Li, Jun Cai, Li Liu, Xiao-Ping Miao, Ying Liu, Hui Li，Evaluation of Genetic Susceptibility Loci for Chronic Hepatitis B in Chinese: Two Independent Case-Control Studies. PLoS One, 2011 Mar 8;6(3):e17608.\r
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18． Xianglan Jin, He Cheng, Jie Chen, Dahai Zhu*. RNF13: An Emerging RING Finger Ubiquitin Ligase Important in Cell Proliferation. FEBS J. 2011 Jan;278(1):78-84. [Epub 2010 Oct 21]\r
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19． Yuewen Chen, Jianwei Ye, Lingzhi Cao, Yong Zhang, Weibo Xia and Dahai Zhu*. Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells. Int J Biochem Cell Biol. 2010 Dec;42(12):2072-81. Epub 2010 Sep 29.\r
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20． Tingting Li, Xueya Zhou, Xiaowo Wang, Dahai Zhu*, Yong Zhang*. Identification and Characterization of Human snoRNA Core Promoters. Genomics. 2010 July; 96(1): 50-56.\r
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21． Yong Zhang, Jun Liu, Chunshi Jia, Tingting Li, Rimao Wu, Jie Wang, Ying Chen, Xiaoting Zou, Runsheng Chen, Xiu-Jie Wang, Dahai Zhu*. Systematic identification and evolutionary features of rhesus monkey small nucleolar RNAs. BMC Genomics. 2010 Jan 25;11(1):61.\r
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22． Qiang Zhang, Kun Wang, Yong Zhang, Jiao Meng, Fang Yu, Yan Chen, Dahai Zhu*. The myostatin-induced E3 ubiquitin ligase RNF13 negatively regulates the proliferation of chicken myoblasts. FEBS J. 2010 Jan;277(2):466-76. Epub 2009 Dec 15.\r
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23． Yong Zhang, Jie Wang, Shoujun Huang, Xiaopeng Zhu, Jun Liu, Ning Yang, Dandan Song, Rimao Wu, Wei Deng, Geir Skogerbø, Xiu-Jie Wang, Runsheng Chen, Dahai Zhu*. Systematic identification and characterization of chicken (Gallus gallus) ncRNAs. Nucleic Acids Res. 2009 Oct;37(19):6562-74. Epub 2009 Aug 31.\r
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24． Yuewen Chen, Lingzhi Cao, Jianwei Ye, Dahai Zhu*. Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin. Biochem Biophys Res Commun, 2009 Oct 9; 388(1):112-6. Epub 2009 Jul 30.\r
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25． Qi Zheng, Yong Zhang, Ying Chen, Ning Yang, Xiu-Jie Wang and Dahai Zhu*. Systematic identification of genes involved in divergent skeletal muscle growth rates of broiler and layer chickens. BMC Genomics, 2009 Feb 22;10:87.\r
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26． Qiang Zhang, Yun-Xiao Meng, Lei Zhang, Jie Chen, Dahai Zhu*. RNF13 a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer. Cell Research. 2009 Mar;19(3):348-57.\r
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27． Ming Ji, Qiang Zhang, Jianwei Ye, Xueyan Wang, Wei Yang, Dahai Zhu*. Myostatin induces p300 degradation to silence cyclin D1 expression through the PI3K/PTEN/Akt pathway. Cellular Signal, 2008 Aug;20(8):1452-8. Epub 2008 Apr 1.\r
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28． Jianwei Ye, Yong Zhang, Jialin Xu, Qiang Zhang, Dahai Zhu*. FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy. Gene. 2007 Dec 1;404(1-2):53-60. Epub 2007 Sep 7.\r
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29． Wei Yang, Yong Zhang, Yanfeng Li, Zhenguo Wu and Dahai Zhu*. Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1. J. Biol. Chem., 2007 Feb 9;282(6):3799-808. Epub 2006 Nov 27.\r
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30． Yong Zhang, Jianwei Ye, Dazhi Chen, Xinyi Zhao, Xingjun Xiao, Sheng Tai, Wei Yang, Dahai Zhu*. Differential Expression Profiling Between the Relative Normal and Dystrophic Muscle Tissues from the Same LGMD Patient. J Transl Med, 2006, 4: 53.\r
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31． Xujun Ma, Qian Qian, Chuanping Yang, Guifeng Liu and Dahai Zhu*. Effect of mouse calcineurin on induction and growth of rice callus transformed by the calcineurin gene. Plant Cell, Tissue and Organ Culture, 2006, 86: 1-6.\r
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32． Wei Yang, Yan Chen, Yong Zhang, Xueyan Wang, Ning Yang, and Dahai Zhu*. Erk1/2 mitogen-activated protein kinase pathway involves in myostatin-regulated differentiation repression. Cancer Res, 2006, 66 (3): 1-7.\r
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33． Xujun Ma, Qian Qian, and Dahai Zhu*. Expression of a calcineurin gene improves salt stress tolerance in transgenic rice. Plant Molecular Biology 2005, 58: 483-495.\r
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34． Wei Yang,Yong Zhang, Guoda Ma, Xinyi Zhao, Yan Chen and Dahai Zhu*. Identification of gene expression modifications in myostatin stimulated myoblasts. Biochem Biophys Res Commun. 2005, 326: 660-666.\r
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35． Zhiliang Gu, Yong Zhang, Peng Shi, Ya-Ping Zhang, Dahai Zhu*, Hui Li. Phylogenetic Analysis of Myostatin Gene in Avian Species. Animal Genetics 2004, 35 (6): 470-472.\r
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36． Zhiliang Gu, Dahai Zhu, Ning Li, Hui Li, Xuemei Deng, Changxin Wu. The Single Nucleotide Polymorphisms of the Chicken Myostatin Gene are Associated with Skeletal Muscle and Adipose Growth. Science in China 2004, 47:26-31.\r
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37． Yanxia Li, Dongcheng Wu, Biao Chen, Alistair Ingram, Lizhi He, Lieqi Liu, Dahai Zhu, Anil Kapoor and Damu Tang. ATM activity contributes to the tumor-suppressing function of p14ARF. Oncogene 2004, 1-11.\r
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38． Haixia Wang, Qiang Zhang, Dahai Zhu*. hSGT Interacts with the N-terminal Region of Myostatin. Biochem Biophys Res Commun. 2003, 311: 877-883.