个人简历

Professional Experience:\r
2019.04-Present Tenure-Track Assistant Professor, School of Pharmaceutical Sciences, Peking University Principal Investigator, State Key Laboratory of Natural and Biomimetic Drugs\r
2016-2019 Postdoc in Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany (Advisor: Professor Herbert Waldmann)\r
2009-2011 Research Assistant in Chemistry Center, National Institute of Biological Sciences, Beijing, China (Advisor: Professor Xiaoguang Lei)\r
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Education:\r
2011-2016 Ph.D. in Organic Chemistry, University of Geneva, Geneva, Switzerland (Advisor: Professor Clément Mazet)\r
2006-2009 M.S. in Chemical Biology, Peking University, Beijing, China (Advisor: Professor Xin-Shan Ye)\r
2002-2006 B.S. in Pharmaceutical Sciences, Peking University, Beijing, China

研究领域

"""""1. Total Synthesis of Bioactive Natural Products\r
2. Cellular Targets Identification and Elucidation of the Mechanism of Action (MoA) of Natural Products\r
3. Natural Product Research for Translational Medicine and Therapeutics"

近期论文

Benke Hong, Weilong Liu, Jin Wang, Jinbao Wu, Yuichiro Kadonaga, Pei-Jun Cai, Hong-Xiang Lou, Zhi-Xiang Yu, Houhua Li,* Xiaoguang Lei,* Chem 2019, 5, 1671-1681(Highlighted in C... Link 24. Benke Hong, Weilong Liu, Jin Wang, Jinbao Wu, Yuichiro Kadonaga, Pei-Jun Cai, Hong-Xiang Lou, Zhi-Xiang Yu, Houhua Li,* Xiaoguang Lei,* Chem 2019, 5, 1671-1681(Highlighted in Chem 2019, 5, 1368-1370).\r
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Houhua Li, Rajesh Gontla, Jana Flegel, Christian Merten, Slava Ziegler, Andrey P. Antonchick,* Herbert Waldmann*, Angew. Chem. Int. Ed. 2019, 58, 307-311. Link 23. Houhua Li, Rajesh Gontla, Jana Flegel, Christian Merten, Slava Ziegler, Andrey P. Antonchick,* Herbert Waldmann*, Angew. Chem. Int. Ed. 2019, 58, 307-311.\r
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Gang Shan, Jana Flegel, Houhua Li, Christian Merten, Slava Ziegler, Andrey P. Antonchick,* Herbert Waldmann*, Angew. Chem. Int. Ed. 2018, 57, 14250-14254. Link 22. Gang Shan, Jana Flegel, Houhua Li, Christian Merten, Slava Ziegler, Andrey P. Antonchick,* Herbert Waldmann*, Angew. Chem. Int. Ed. 2018, 57, 14250-14254. \r
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Zongwei Yue, Xinhua Xiao, Jinbao Wu, Xiaozhou Zhou, Weilong Liu, Yaxi Liu, Houhua Li, Guoqiang Chen, Yingli Wu,* Xiaoguang Lei*, J. Nat. Prod. 2018, 81, 298-306. Link 21. Zongwei Yue, Xinhua Xiao, Jinbao Wu, Xiaozhou Zhou, Weilong Liu, Yaxi Liu, Houhua Li, Guoqiang Chen, Yingli Wu,* Xiaoguang Lei*, J. Nat. Prod. 2018, 81, 298-306.\r
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Houhua Li, Xiaoguang Lei*, Chem. Rec. 2018, 18, 543-554. Link 20. Houhua Li, Xiaoguang Lei*, Chem. Rec. 2018, 18, 543-554.\r
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Benke Hong, Dachao Hu, Jinbao Wu, Jing Zhang, Houhua Li, Yingming Pan, Xiaoguang Lei*, Chem. Asian J. 2017, 12, 1557-1567 (Selected as a Very Important Paper). Link 19. Benke Hong, Dachao Hu, Jinbao Wu, Jing Zhang, Houhua Li, Yingming Pan, Xiaoguang Lei*, Chem. Asian J. 2017, 12, 1557-1567 (Selected as a Very Important Paper).\r
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Houhua Li†, Daniele Fiorito†(†co-first author), Clément Mazet*, ACS Catal. 2017, 7, 1554-1562. Link 18. Houhua Li†, Daniele Fiorito†(†co-first author), Clément Mazet*, ACS Catal. 2017, 7, 1554-1562.\r
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Houhua Li, Clément Mazet*, Acc. Chem. Res. 2016, 49, 1232-1241. Link 17. Houhua Li, Clément Mazet*, Acc. Chem. Res. 2016, 49, 1232-1241.\r
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Weilong Liu†, Houhua Li†(†co-first author), Peijun Cai, Zhen Wang, Zhi-Xiang Yu, Xiaoguang Lei*, Angew. Chem. Int. Ed. 2016, 55, 3112-3116(Highlighted in Synfacts 2016, 12, 33... Link 16. Weilong Liu†, Houhua Li†(†co-first author), Peijun Cai, Zhen Wang, Zhi-Xiang Yu, Xiaoguang Lei*, Angew. Chem. Int. Ed. 2016, 55, 3112-3116(Highlighted in Synfacts 2016, 12, 332 & Org. Chem. Highlights 2017, August 28).\r
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Houhua Li, Clément Mazet* 1.6.9 Organometallic Complexes of Iridium (Update 2015), Science of Synthesis Knowledge Updates, Georg Thieme Verlag KG, Stuttgart, 2016, 21-58. Link 15. Houhua Li, Clément Mazet* 1.6.9 Organometallic Complexes of Iridium (Update 2015), Science of Synthesis Knowledge Updates, Georg Thieme Verlag KG, Stuttgart, 2016, 21-58.\r
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B. Zhang, S. Kaziz, H. Li, D. Wodka, S. Malola, O. Safonova, M. Nachtegaal, C. Mazet, I. Dolamic, J. Llorca, E. Kalenius, L. M. L. Daku, H. Hakkinen, T. Bürgi,* N. Barrabés*, N... Link 14. B. Zhang, S. Kaziz, H. Li, D. Wodka, S. Malola, O. Safonova, M. Nachtegaal, C. Mazet, I. Dolamic, J. Llorca, E. Kalenius, L. M. L. Daku, H. Hakkinen, T. Bürgi,* N. Barrabés*, Nanoscale 2015, 7, 17012-17019.\r
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B. Hong, C. Li, Z. Wang, J. Chen, H. Li,* X. Lei*, J. Am. Chem. Soc. 2015, 137, 11946-11949 (Highlighted in C&E News 2015, 93, 35; Synfacts 2015, 11, 1231; Chin. J. Org. Chem. ... Link 13. B. Hong, C. Li, Z. Wang, J. Chen, H. Li,* X. Lei*, J. Am. Chem. Soc. 2015, 137, 11946-11949 (Highlighted in C&E News 2015, 93, 35; Synfacts 2015, 11, 1231; Chin. J. Org. Chem. 2015, 35, 2445; Org. Chem. Highlights 2016, September 26).\r
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Houhua Li, Clément Mazet*, J. Am. Chem. Soc. 2015, 137, 10720-10727 (Highlighted in Synform 2016, A21-A24). Link 12. Houhua Li, Clément Mazet*, J. Am. Chem. Soc. 2015, 137, 10720-10727 (Highlighted in Synform 2016, A21-A24).\r
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Bei Zhang, Sameh Kaziz, Houhua Li, Miguel González Hevia, Dawid Wodka, Clément Mazet, Thomas Bürgi,* Noelia Barrabés*, J. Phys. Chem. C 2015, 119, 11193-11199. Link 11. Bei Zhang, Sameh Kaziz, Houhua Li, Miguel González Hevia, Dawid Wodka, Clément Mazet, Thomas Bürgi,* Noelia Barrabés*, J. Phys. Chem. C 2015, 119, 11193-11199.\r
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Benke Hong†, Houhua Li†(†co-first author), Jinbao Wu, Jing Zhang, Xiaoguang Lei*, Angew. Chem. Int. Ed. 2015, 54, 1011-1015 (Highlighted in Synfacts 2015, 11, 112; Org. Chem. ... Link 10. Benke Hong†, Houhua Li†(†co-first author), Jinbao Wu, Jing Zhang, Xiaoguang Lei*, Angew. Chem. Int. Ed. 2015, 54, 1011-1015 (Highlighted in Synfacts 2015, 11, 112; Org. Chem. Highlights 2015, December 14).\r
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Jing Zhang, Jinbao Wu, Benke Hong, Wenying Ai, Xiaoming Wang, Houhua Li, Xiaoguang Lei*, Nat. Commun. 2014, 5, 4614. Link 9. Jing Zhang, Jinbao Wu, Benke Hong, Wenying Ai, Xiaoming Wang, Houhua Li, Xiaoguang Lei*, Nat. Commun. 2014, 5, 4614.\r
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Evgeny Larionov, Houhua Li, Clément Mazet*, Chem. Commun. 2014, 50, 9816-9826. Link 8. Evgeny Larionov, Houhua Li, Clément Mazet*, Chem. Commun. 2014, 50, 9816-9826.\r
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Houhua Li, Clément Mazet*, Org. Lett. 2013, 15, 6170-6173. Link 7. Houhua Li, Clément Mazet*, Org. Lett. 2013, 15, 6170-6173.\r
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Houhua Li†, Xiaoming Wang†(†co-first author), Benke Hong, Xiaoguang Lei*, J. Org. Chem. 2013, 78, 800-821 (Selected as the Featured and Cover Article). Link 6. Houhua Li†, Xiaoming Wang†(†co-first author), Benke Hong, Xiaoguang Lei*, J. Org. Chem. 2013, 78, 800-821 (Selected as the Featured and Cover Article).\r
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Xiaoming Wang, Houhua Li, Xiaoguang Lei*, Synlett 2013, 24, 1032-1043 (Invited Synpacts Article). Link