个人简历

2001 PhD Doctor of Philosophy – Cell Biology University of Dundee
1995 BSc Bachelor of Science – Biochemistry University of Dundee

近期论文

Davies, H. M., Thalassinos, K., & Osborne, A. R. (2016). Expansion of Lysine-rich Repeats in Plasmodium Proteins Generates Novel Localisation Sequences that Target the Periphery of the Host Erythrocyte. J Biol Chem. doi:10.1074/jbc.M116.761213
Tarr, S. J., & Osborne, A. R. (2015). Experimental determination of the membrane topology of the Plasmodium protease Plasmepsin V. PloS one, 10 (4), e0121786-?.
Tarr, S. J., Moon, R. W., Hardege, I., & Osborne, A. R. (2014). A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Mol Biochem Parasitol, 196 (1), 29-40. doi:10.1016/j.molbiopara.2014.07.011
Tarr, S. J., Cryar, A., Thalassinos, K., Haldar, K., & Osborne, A. R. (2013). The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Mol Microbiol, 87 (4), 835-850. doi:10.1111/mmi.12133
Osborne, A. R., Speicher, K. D., Tamez, P. A., Bhattacharjee, S., Speicher, D. W., & Haldar, K. (2010). The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. , 171, 25-31.
Erlandson, K. J., Miller, S. B., Nam, Y., Osborne, A. R., Zimmer, J., & Rapoport, T. A. (2008). A role for the two-helix finger of the SecA ATPase in protein translocation. , 455, 984-987.
Erlandson, K. J., Or, E., Osborne, A. R., & Rapoport, T. A. (2008). Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. , 283, 15709-15715.
Osborne, A. R., & Rapoport, T. A. (2007). Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. , 129, 97-110.
Menetret, J. F., Schaletzky, J., Clemons, W. M., Osborne, A. R., Skanland, S. S., Denison, C., . . . Akey, C. W. (2007). Ribosome binding of a single copy of the SecY complex: implications for protein translocation. , 28, 1083-1092.
Osborne, A., Flett, A., & Smythe, E. (2005). Endocytosis assays in intact and permeabilized cells. , Chapter 11, Unit 11 18-?.
Osborne, A. R., Rapoport, T. A., & van den Berg, B. (2005). Protein translocation by the Sec61/SecY channel. , 21, 529-550.
Osborne, A. R., Clemons, W. M., & Rapoport, T. A. (2004). A large conformational change of the translocation ATPase SecA. , 101, 10937-10942.
Ye, J., Osborne, A. R., Groll, M., & Rapoport, T. A. (2004). RecA-like motor ATPases--lessons from structures. , 1659, 1-18.
Antoniou, A. N., Ford, S., Alphey, M., Osborne, A., Elliott, T., & Powis, S. J. (2002). The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules. , 21, 2655-2663.
McLauchlan, H., Newell, J., Morrice, N., Osborne, A., West, M., & Smythe, E. (1998). A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits. , 8, 34-45.