个人简历

2016 Reader (Associate Professor) in Molecular Cell Biology
2015 Fellow of the Higher Education Academy (FHEA)
2014 Lister Institute Research Prize
2011 - 2016 BBSRC David Phillips Research Fellow, University College London, London (UK)
2008 - 2011 MRC Postdoctoral Fellow, MRC Laboratory of Molecular Biology, Cambridge (UK)
2006 - 2008 HFSP Postdoctoral Fellow, Harvard Medical School, Boston (US)
2005 - 2006 EMBO Postdoctoral Fellow, Harvard Medical School, Boston (US)
2001 - 2005 PhD in Immunology, University of Aix-Marseille II, Marseille (France)

近期论文

Boucrot, E., Ferreira, A. P., Almeida-Souza, L., Debard, S., Vallis, Y., Howard, G., . . . McMahon, H. T. (2015). Endophilin marks and controls a clathrin-independent endocytic pathway. Nature, 517 (7535), 460-465. doi:10.1038/nature14067
Renard, H. F., Simunovic, M., Lemière, J., Boucrot, E., Garcia-Castillo, M. D., Arumugam, S., . . . Johannes, L. (2015). Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature, 517 (7535), 493-496. doi:10.1038/nature14064
Santos, A. J., Meinecke, M., Fessler, M. B., Holden, D. W., & Boucrot, E. (2013). Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase. J Cell Sci, 126 (Pt 14), 2990-2996. doi:10.1242/jcs.115253
Boucrot, E., Pick, A., Çamdere, G., Liska, N., Evergren, E., McMahon, H. T., & Kozlov, M. M. (2012). Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains. Cell, 149 (1), 124-136. doi:10.1016/j.cell.2012.01.047
McMahon, H. T., & Boucrot, E. (2011). Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol, 12 (8), 517-533.
Henne, W. M., Boucrot, E., Meinecke, M., Evergren, E., Vallis, Y., Mittal, R., & McMahon, H. T. (2010). FCHo proteins are nucleators of clathrin-mediated endocytosis. Science, 328 (5983), 1281-1284.
Boucrot, E., Henry, T., Borg, J. P., Gorvel, J. P., & Méresse, S. (2005). The intracellular fate of Salmonella depends on the recruitment of kinesin. Science, 308 (5725), 1174-1178.
Santos, A. J., Durkin, C. H., Helaine, S., Boucrot, E., & Holden, D. W. (2016). Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis. Infection and immunity, 84 (7), 2149-2158.
McMahon, H. T., & Boucrot, E. (2015). Membrane curvature at a glance. Journal of cell science, 128 (6), 1065-1070.
Tacheva-Grigorova, S. K., Santos, A. J., Boucrot, E., & Kirchhausen, T. (2013). Clathrin-mediated endocytosis persists during unperturbed mitosis. Cell Rep, 4 (4), 659-668. doi:10.1016/j.celrep.2013.07.017
Meinecke, M., Boucrot, E., Camdere, G., Hon, W. C., Mittal, R., & McMahon, H. T. (2013). Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission. J Biol Chem, 288 (9), 6651-6661. doi:10.1074/jbc.M112.444869
Thiery, J., Keefe, D., Boulant, S., Boucrot, E., Walch, M., Martinvalet, D., . . . Lieberman, J. (2011). Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol, 12 (8), 770-777. doi:10.1038/ni.2050
Boucrot, E., Howes, M. T., Kirchhausen, T., & Parton, R. G. (2011). Redistribution of caveolae during mitosis. J Cell Sci, 124 (Pt15), 1965-1972.
Boucrot, E., & McMahon, H. T. (2011). [Nucleation of clathrin-coated pits - « membrane sculptors » at work]. Med Sci (Paris), 27 (2), 122-125. doi:10.1051/medsci/2011272122
Thiery, J., Keefe, D., Saffarian, S., Martinvalet, D., Walch, M., Boucrot, E., . . . Lieberman, J. (2010). Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis. Blood, 115 (8), 1582-1593. doi:10.1182/blood-2009-10-246116
Boucrot, E., Saffarian, S., Zhang, R. Y., & Kirchhausen, T. (2010). Roles of AP-2 during clathrin-mediated endocytosis. PLoS One, 5 (5), e10597-?.
Dumont, A., Boucrot, E., Drevensek, S., Daire, V., Gorvel, J. P., Poüs, C., . . . Méresse, S. (2010). SKIP, the host target of the Salmonella virulence factor SifA, promotes kinesin-1-dependent vacuolar membrane exchanges. Traffic, 11 (7), 899-911. doi:10.1111/j.1600-0854.2010.01069.x
Boucrot, E., & Kirchhausen, T. (2008). Mammalian cells change volume during mitosis. PLoS One, 3 (1), e1477-?.
Boucrot, E. (2008). [What does the plasma membrane do during mitosis?]. Med Sci (Paris), 24 (1), 34-36. doi:10.1051/medsci/200824134
Boucrot, E., & Kirchhausen, T. (2007). Endocytic recycling controls plasma membrane area during mitosis. Proc Natl Acad Sci USA, 104 (19), 7939-7944.
Veiga, E., Guttman, J. A., Bonazzi, M., Boucrot, E., Toledo-Arana, A., Lin, A. E., . . . Cossart, P. (2007). Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe, 2 (5), 340-351. doi:10.1016/j.chom.2007.10.001
Ma, Y. M., Boucrot, E., Villén, J., Affar, E. L. B., Gygi, S. P., Göttlinger, H. G., & Kirchhausen, T. (2007). Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. J Biol Chem, 282 (13), 9805-9812. doi:10.1074/jbc.M611635200
Macia, E., Ehrlich, M., Massol, R., Boucrot, E., Brunner, C., & Kirchhausen, T. (2006). Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell, 10 (6), 839-850. doi:10.1016/j.devcel.2006.04.002
Boucrot, E., Saffarian, S., Massol, R., Kirchhausen, T., & Ehrlich, M. (2006). Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res, 312 (20), 4036-48.
Henry, T., Couillault, C., Rockenfeller, P., Boucrot, E., Dumont, A., Schroeder, N., . . . Méresse, S. (2006). The Salmonella effector protein PipB2 is a linker for kinesin-1. Proc Natl Acad Sci U S A, 103 (36), 13497-13502. doi:10.1073/pnas.0605443103