个人简历

Education
Ph.D Case Western Reserve University 1974
B.S. University of Michigan 1970
Research Fellow National Institutes of Health 1978-1983
Professional Experience
Associate Professor Baylor University 1983-Present
Visiting Scientist National Institutes of Health 1988, 1989, 1991

近期论文

AlAsiri, S., Basit, S., Wood-Trageser, M.A., Yatsenko, S.A., Jeffries, E.P., Surti, U., Ketterer, D.M., Afzal, S., Ramzan, R., Faiyaz-Ul Haque, M., Jiang, H, Trakselis, M.A., Rajkovic, A. (2015) Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability. J. Clin. Invest., 125 (1), 754-62. link
Wood-Trageser, M.A., Gurbuz, F., Yatsenko, S.A., Jeffries, E.P., Kotan, L.D., Surti, U., Ketterer, D.M., Matic, J., Chipkin, J., Jiang, H, Trakselis, M.A., Topaloglu, A.K., Rajkovic, A. (2014) Exome sequencing identifies MCM9 mutations in ovarian failure, short stature and chromosomal instability. Am. J. Hum. Genetics, 95 (6), 754-762. link
Nucleic Acid Polymerases, Murakami, K. and Trakselis, M.A. (Eds.), Nucleic Acids and Molecular Biology Vol. 30, Berlin, Germany, Springer. 2014. link
Trakselis, M.A. and Murakami, K. Introduction to Nucleic Acid Polymerases: Families, Themes, and Mechanisms, (Chapter 1), Nucleic Acid Polymerases, Murakami, K. and Trakselis, M.A. (Eds.), Nucleic Acids and Molecular Biology Vol. 30, Berlin, Germany, Springer. 2014. link
Trakselis, M.A. and Bauer, R.J. Archaeal DNA Polymerases: Enzymatic Abilities, Coordination, and Unique Properties, (Chapter 6), Nucleic Acid Polymerases, Murakami, K. and Trakselis, M.A. (Eds.), Nucleic Acids and Molecular Biology Vol. 30, Berlin, Germany, Springer. 2014. link
Bauer, R.J., Wolff, I.D., Zuo, X., Lin, H-K., Trakselis, M.A. (2013) Assembly and Distributive Action of an Archaeal DNA Polymerase Holoenzyme. Special Issue of J. Mol. Biol. entitled “DNA replication & Genomic instability – Replicon Theory”, 425 (230), 4820-36. link
Mohan S., Das, D., Bauer R.J., Heroux A., Zalewski, J.K., Heber, S., Dosunmu-Oqunbi, A.M., Trakselis, M.A., Hildebrand J.D., and VanDemark A.P (2013) Structure of a Highly Conserved Domain of Rock1 Required for Shroom-mediated Regulation of Cell Morphology. PLOS One, 8(12), e81075. link
van Dongen, S.F.M., Clerx, J., Nørgaard, K., Bloemberg. T.G., Cornelissen, J.J.L.M., Trakselis, M.A., Nelson, S.W., Benkovic, S.J., Rowan, A.E., Nolte, R.J.M. A Clamp-Shaped Bio-Hybrid Catalyst for DNA Oxidation. Nature Chem., 5(11), 946-51. link
Jeffries, E.P., Denq, W.I., Bartko, J.C., and Trakselis, M.A. (2013) Identification, Quantification, and Evolutionary Analysis of a Novel Isoform of MCM9, Gene, 519, 41-49. link
Bauer, R.J., Graham, B.W., and Trakselis, M.A. (2013) Novel Interaction of the Bacterial-like DnaG Primase with the MCM Helicase in Archaea, J. Mol. Biol., 8(26), 1259-1273. link
Trakselis, M.A. and Graham, B.W. (2012) Biochemisty: Molecular Hurdles Cleared with Ease, Nature, 492, 195-197. link
Lin, H-K., Chase, S.F., Laue, T.M., Jen-Jacobsen, L., and Trakselis, M.A. (2012) Differential Temperature Dependent Multimeric Assemblies of Replication and Repair Polymerases on DNA Increase Processivity. Biochemistry,51, 7367-7382. link
Mohan, S., Rizaldy, R., Das D., Bauer R.J., Heroux A., Trakselis, M.A., Hildebrand J.D., Vandemark, A.P. (2012) Structure of the shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, rock binding, and apical constriction, Mol. Biol. Cell, 23, 2131-2142. link
Bauer, R.J., Begley M.T., and Trakselis, M.A. (2012) Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus, Biochemistry, 51, 1996-2007. link
Zuo, Z., Lin, H-K, and Trakselis, M.A. (2011) Strand annealing and terminal transferase activities of a B-family DNA Polymerase, Biochemistry, 50, 5379-5370. link
Graham, B.W., Schauer, G.D., Leuba, S.H. and Trakselis, M.A. (2011) Steric Exclusion and Wrapping of the Excluded DNA Strand Occurs Along Discrete External Binding Paths During MCM Helicase Unwinding, NAR, 39, 6585. link
Zuo, Z., Rodgers, C., Mikheikin, A.L., and Trakselis, M.A. (2010) Characterization of a functional DnaG-type primase in Archaea: Implications for a dual primase system, J. Mol. Biol., 397, 664-676. link
Mikheikin A.L., Lin, H-K, Mehta, P., Jen-Jacobson, L., and Trakselis, M.A. (2009) The DNA replication polymerase from Sulfolobus solfataricus forms a multimer when bound to DNA, NAR, 37, 7194-205. link
Rothenberg, E., Trakselis, M.A., Bell, S.D., and Ha, T. (2007) MCM Forked substrate specificity involves dynamic interaction with the 5′-tail. JBC, 282, 34229-34. link
McGeoch, A.T., Trakselis, M.A., Laskey, R.A., and Bell, S.D. (2005) Organization of the Archaeal MCM Complex on DNA and Implications for a Helicase Mechanism. Nat Struc. Mol. Biol., 12, 756-762. (Cover) link