个人简历

Education
B.S., Biochemistry and Biophysics, Washington State University, May, 1999
Ph.D., Inorganic Chemistry, University of California, Los Angeles, Dec. 2005
Post-doctoral fellow, Harvard University 2006-2010
Appointed to Faculty at Baylor University, August 2010

近期论文

Schneider, G.F., Shaw, B.F., Carrilho, E., Lee, A., Whitesides, G.M. Unfolding of ubiquitin with SDS studied by capillary electrophoresis. J. Am. Chem. Soc. 2008; 130(51): 17384-93.
Shaw, B.F., Schneider, G.F., Bilgicer, B., Kaufman, G.K., Neveu, J.M., Lane, W.S., Whitelegge, J.P., Whitesides, G.M. Lysine acetylation can generate highly charged enzymes with increased resistance towards irreversible inactivation. Protein Sci. 2008; 17(8): 1446-1455.
Kaufman, G.K., Thomas, S.W., Reches, M., Feng, J., Shaw, B.F., Whitesides, G.M. Phase separation of 2D Coulombic crystals of meso-scale dipolar particles from meso-scale polarizable “solvent.” App. Phys. Lett. 2009; 94 (4): 44102.
Kaufman, G.K., Thomas, S.W., Reches, M., Shaw, B.F., Feng, J., Whitesides, G.M. Phase separation of 2D meso-scale Coulombic crystals from meso-scale polarizable “solvent.” Soft Matter 2009; 5: 1188-1191.
Durer, Z., Cohlberg, J.A., Dinh, P., Padua, S., Ehrenclou, K., Downes, S., Tan, J.K., Nakano, Y., Bowman, C.J., Rosales, J., Hoskins, J.L., Kwon, C., Mason, A.Z., Rodriguez, J.A., Doucette, P.A., Shaw, B.F., Valentine, J.S. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote amyloid formation from superoxide dismutase. PLoS ONE 2009; 4(3): e5004.
Bilgicer, B., Thomas, S.W., Shaw, B.F., Kaufman, G.K., Krishnamurthy, V.M., Estroff, L.A., Whitesides, G.M. A non-chromatographic method for the purification of a bivalent monoclonal IgG antibody from biological fluid. J. Am. Chem. Soc. 2009; 131(26): 9361-7.
Durazo, A., Shaw, B.F., Chattopadhyay, M., Faull, K.F., Valentine, J.S., Whitelegge, J.P. Metal free wild-type superoxide dismutase-1 and three different ALS variants share a similar partially unfolded β-barrel at physiological temperature. J. Biol. Chem. 2009; 284(49): 34382-9.
Shaw, B.F.*, Arthanari, H., Lee, A., Durazo, A., Frueh, D.P., Pollastri, M.P., Bilgicer, B., Gygi, S.P., Wagner, G., Whitesides, G.M.* Neutralizing positive charges at the surface of a protein lowers its rate of amide H/D exchange without altering its structure or raising its thermostability. J. Am. Chem. Soc. 2010; 132 (49): 17411-17425
Shaw, B.F.*, Schneider, G.F., Arthanari, H., Narovlyansky, M., Moustakas, D., Durazo, A., Wagner, G., Whitesides, G.M.* Complexes of native Ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. J. Am. Chem. Soc. 2011; 133(44): 17681-17695.
Shaw, B.F.*, Schneider, G.F., Whitesides, G.M.* Effect of Surfactant Hydrophobicity on the Pathway for Unfolding of Ubiquitin J. Am. Chem. Soc. 2012; 134(45):18739-18745.
Shi Y., Mowery R.A., Ashley J., Hentz M., Ramirez A.J., Bilgicer B., Slunt-Brown H., Borchelt D.R., Shaw B.F.* Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding. Protein Sci. 2012; 21(8):1197-1209.
Krishnamurthy, V.J., Raman, V.S., Mowery, R.A., Hentz, M., Balega, J.D., Shaw, B.F., Kumar, K. Ligand-Induced Protein Mobility in Complexes of Carbonic Anhydrase II and Benzenesulfonamides with Oligoglycine Chains. PLoS ONE. 2013; 8(3): e57629.
Alves, N.J., Champion, M.M., Stefanick, J.F., Handlogten, M.W., Moustakas, D.T., Shi, Y., Shaw, B.F., Navari, R.M., Kiziltepe, T., Bilgicer, B. Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site. Biomaterials. 2013; 34(22): 5700-5710.
Shi Y, Mowery RA, Shaw BF. Effect of Metal Loading and Subcellular pH on Net Charge of Superoxide Dismutase-1. J Mol Biol. 2013;425(22):4388-404
Abdolvahabi, A., Taylor B.W., Holden R.L., Shaw E.V., Kentsis A., Rodriguez-Galindo C., Mukai S., Shaw, B.F. Colorimetric and Longitudinal Analysis of Leukocoria in Recreational Photographs of Children with Retinoblastoma. PLoS ONE. 2013
Shi Y, Rhodes NR, Abdolvahabi A, Kohn T, Cook NP, Marti AA, Shaw BF. Deamidation of Asparagine to Aspartate Destabilizes Cu, Zn Superoxide Dismutase, Accelerates Fibrillization, and Mirrors ALS-Linked Mutations. J Am Chem Soc. 2013;135(42):15897-908.
Shi, Y., Abdolvahabi, A. & Shaw, B. F. Protein charge ladders reveal that the net charge of ALS-linked superoxide dismutase can be different in sign and magnitude from predicted values. Protein Sci. 2014, [Epub ahead of print].
Rivas-Perea, P., Baker, E., Hamerly, G. & Shaw, B. F. Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings. BMC Ophthalmol. 2014; 14, 110.
Abdolvahabi, A., Gober, J. L., Mowery, R. A., Shi, Y. & Shaw, B. F. Metal Ion-Specific Screening of Charge Effects in Protein Amide H/D Exchange Follows the Hofmeister Series. Anal Chem. 2014,86, 10303-10.
Abdolvahabi, A.; Shi, Y.; Rhodes, N. R.; Cook, N. P.; Marti, A. A.; Shaw, B. F. Arresting Amyloid with Coulomb's Law: Acetylation of ALS-Linked SOD1 by Aspirin Impedes Aggregation. Biophys J. 2015, 108, 1199-212.