近期论文

S. Sau, A. Larsen, and J. Chaput. (2014) Automated Solid-Phase Synthesis of High Capacity Olido-dT Cellulose. Bioorg. Med. Chem. Lett. 24. (24): 5692-5694r
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J. Chaput (2014) Replicating an Expanded Genetic Alphabet in Cells. ChemBioChem. 15 (3): 1869-1871.r
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A. Larsen, A. Gillig, P. Shah, S. Sau, K. Fenton and J. Chaput. (2014) A General Approach for Characterizing In Vitro Selected Peptides with Protein Binding Affinity. Analytical Chemistry. 86 (15): 7219-7223r
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M. Dunn and J.C. Chaput (2014) An In Vitro Selection Protocol for Threose Nucleic Acid (TNA) using DNA Display. (2014) Curr. Protoc. Nucleic Acid Chem. 57:9.8:9..8.1-9.8.19r
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J. Saul, B. Petritis, S. Sau, F. Rauf, M. Gaskin, B. Ober-Reynolds, I. Mineyev, M. Magee, J.C. Chaput, J. Qiu, J. LaBaer. (2014) Development of a Full-Length Human Protein Production Pipeline. Protein Science. 23 (8): 1123-1135.r
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B.P. Wellensiek, A.C. Larsen, J. Flores, B.L. Jacobs, J.C. Chaput (2013). A Novel Leader Sequence Capable of Rapid and High Protein Sythesis in Mammalian Cells. Protein Science. 22: 1392-1398.r
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B.P. Wellensiek, A.C. Larsen, B. Stephens, K. Kukurba, K. Waern, N. Briones, L. Liu, M. Snyder, B.L. Jacobs, S. Kumar, J.C. Chaput (2013) Genome-wide Profiling of Human Cap-independent Translation-enhancing Elements. Nature Methods. Online : June 16 2013. 10(8): 747-750.r
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H. Yu, S. Zhang, M.R. Dunn, and J.C. Chaput (2013) An Efficient and Faithful in Vitro Replication System for Threose Nucleic Acid. J. Am. Chem. Soc. 135(9): 3583-3591.r
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S.B. Korch, J.M. Stomel, M.A. Leon, M.A. Hamada, C.R. Stevenson, B.W. Simpson, S.K. Gujulla and J.C. Chaput. (2013) ATP Sequestration by a Synthetic ATP-Binding Protein Leads to Novel Phenotypic Changes in Escherichia Coli. ACS Chem. Biol. 8(2) 451-456.r
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S. Zhang, and J.C. Chaput. 2013. Synthesis and Enzymatic Incorporation of a-L-Threofuranosyl Adenine Triphosphate (tATP). Bioorg. Med. Chem. Lett. 23(5):1447-1449.r
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S. Zhang, H. Yu, and J.C. Chaput (2013) Synthesis of Threose Nucleic Acid (TNA) Triphosphates and Oligonucleotides by Polymerase-Mediated Primer Extension. Current Protocols in Nucleic Acid Chemistry. 52:4.54:4.54.1–4.54.17.r
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V. Pinheiro, A. Taylor, C. Cozens, M. Abramov, M. Renders, S. Zhang, J. C. Chaput, J. Wengel, S. Peak-Chew, S. McLaughlin, P. Herdewijn, and P. Holliger (2012) Synthetic Genetic Polymers Capable of Heredity and Evolution. Science 336(6079) 341-344.r
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H. Yu, S. Zhang and J. C. Chaput (2012) Darwinian Evolution of an Alternative Genetic System Provides Support for TNA as an RNA Progenitor. Nature Chemistry 4, 183-187.r
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J. C. Chaput, H. Yu, S. Zhang (2012) The Emerging World of Synthetic Genetics. Chemistry & Biology 19(11) 1360-1371.r
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M. Kang, B. Heuberger, J. C. Chaput, C. Switzer, and J. Feigon (2012) Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d(T(iG)4T) in the Presence of Cs+ Ions. Angewandte Chemie International Edition 51, 7952-7955
S. Zhang, J.C. Chaput (2012) Synthesis of Threose Nucleic Acid (TNA) Phosphoramidite Monomers and Oligonuleotide Polymers. Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.51. (Abstract)