个人简历

蒋庆华，国家优秀青年科学基金获得者，国家科技创新2030“新一代人工智能”重大项目评审专家、国家重点研发计划重大项目会议评审专家、教育部长江学者奖励计划评审专家，主要从事复杂疾病的信息获取与处理研究，包括基于单细胞测序技术的肿瘤免疫与神经免疫数据分析理论与方法、肿瘤新生抗原预测模型与算法、mRNA肿瘤治疗性疫苗、基于云的高通量基因组数据分析流程研发，迄今共发表第一或通讯作者SCI论文60余篇，包括1篇《Cell》、1篇《Protein Cell》、6篇《PNAS》、3篇《Nucleic Acids Research》、3篇《Bioinformatics》，单篇SCI最高他引超1200次（google scholar统计）。
主持国家自然科学基金重点项目、优秀青年项目、面上、新冠肺炎应急攻关等项目5项、国家重点研发计划课题1项，作为技术骨干参与国家863计划重大项目2项，2010年获“中国百篇最具影响国际学术论文”、2011年获“第十二届黑龙江省自然科学技术学术成果一等奖”（排名第1）、2012年入选“哈尔滨工业大学基础研究杰出人才培育计划III类”、 2015年入选“哈尔滨工业大学青年拔尖人才选聘计划（破格教授）”、2016年获“国家开发银行科技创新奖”、2017年担任国际著名SCI期刊《Journal of Alzheimer's disease》副主编（Associate Editor, IF: 3.7），2018年入选哈工大基础研究杰出人才“跃升”培育计划，2019年获黑龙江省自然科学一等奖。
荣誉称号
2020年 中国百篇最具影响国际学术论文
2018年 国家优青
2018年 哈工大基础研究杰出人才跃升培育计划
2016年 国家开发银行科技创新奖
2015年 哈尔滨工业大学青年拔尖人才（教授）选聘计划
2012年 哈尔滨工业大学基础研究杰出人才培育计划III
2011年 第十二届黑龙江省自然科学技术学术成果一等奖
2010年 中国百篇最具影响国际学术论文
工作经历
2010.08-2012.12 哈尔滨工业大学 基础交叉研究院 讲师
2011.11-2012.11 哈佛大学 医学院 留学
2013.12-2015.12 哈尔滨工业大学 生命科学与技术学院 副教授
2015.12-至今 哈尔滨工业大学 生命科学与技术学院 教授
2017.11-2020.10 哈尔滨工业大学 生命科学与技术学院 院长助理
2017.05-至今 哈尔滨工业大学 生物信息党支部 党支部书记
教育经历
2007.03-2010.06 哈尔滨工业大学 计算机应用技术 获工学博士学位
2003.09-2006.07 吉林大学 计算数学 获理学硕士学位
1999.09-2003.07 吉林大学 信息与计算科学 获理学学士学位

研究领域

生物信息学""

近期论文

2020
X Ren#, W Wen#, X Fan#, W Hou#, B Su#, P Cai#, J Li#, Y Liu#, F Tang#, F Zhang#, Y Yang#, J He#, W Ma#, J He#, P Wang#, Q Cao, F Chen, Y Che, X Cheng, G Deng, X Deng, W Ding, Y Feng, R Gan, C Guo, W Guo, S He, C Jiang, J Liang, Y Li, J Lin, Y Lin, H Li, J Liu, N Liu, S Liu, M Luo, Q Ma, Q Song, W Sun G Wang, F Wang, YWang, X Wen, Q Wu, G Xu, X Xie, X Xiong, X Xing, H Xu, C Yin, D Yu, K Yu, J Yun, B Zhang, P Zhang, T Zhang, J Zhao, P Zhao, J Zhou, W Zhou, S Zhong, X Zhong, S Zhang, L Zhu, P Zhu, B Zou, J Zou, Z Zuo, F Bai, X Huang, P Zhou*, Qinghua Jiang*, Z Huang*, J Bei*, L Wei*, X Bian*, X Liu*, T Cheng*, X Li,*, P Zhao*, F Wang*, H Wang*, B Su*, Z Zhang*, K Qu*, X Wang*, J Chen*, R Jin*, Z Zhang*. COVID-19 immune features revealed by a large-scale single cell transcriptome atlas. Cell. 2021. DOI: https://doi.org/10.1016/j.cell.2021.01.053 (SCI IF: 38.64)
Fang Li#, Meng Luo#, Wenyang Zhou#, Jinliang Li#, Xiyun Jin, Zhaochun Xu, Liran Juan, Zheng Zhang, Yuou Li, Renqiang Liu, Yiqun Li, Chang Xu, Kexin Ma, Huimin Cao, Jingwei Wang, Pingping Wang*, Zhigao Bu*, Qinghua Jiang*. Single cell RNA and immune repertoire profiling of COVID-19 patients reveal novel neutralizing antibody. Protein Cell. 2020 Nov 25:1-5. doi: 10.1007/s13238-020-00807-6. (SCI IF: 10.16)
Pingping Wang#, Lifen Yao#, Meng Luo#, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Shi Yan, Yiqun Li, Chang Xu, Rui Cheng, Yan Huang, Xiaoyu Lin, Kexin Ma, Hui Cao, Hongxin Liu, Guangfu Xue, Fang Han, Huan Nie, Qinghua Jiang*. Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson's disease. 2021. (SCI IF: 6.255) （Major Revision）
Wenyang Zhou#, Chang Xu#, Pingping Wang, Meng Luo, Zhaochun Xu, Rui Cheng, Xiyun Jin, Yu Guo, Guangfu Xue, Liran Juan, Huan Nie*, Qinghua Jiang*. N439K variant in spike protein alters the infection efficiency and antigenicity of SARS-CoV-2 based on molecular dynamics simulation. (SCI IF: 8.99) （Major Revision）
Xiyun Jin#, Wenyang Zhou#, Meng Luo#, Pingping Wang, Zhaochun Xu, Kexin Ma, Huimin Cao, Chang Xu, Yan Huang, Rui Cheng, Lixing Xiao, Xiaoyu Lin, Fenglan Pang, Yiqun Li, Huan Nie, Qinghua Jiang*. Global characterization of B cell receptor repertoire across COVID-19 patients by single-cell V(D)J sequencing. (SCI IF: 8.99) （Major Revision)
Pingping Wang#, Xiyun Jin#, Wenyang Zhou, Meng Luo, Zhaochun Xu, Chang Xu, Yiqun Li, Kexin Ma, Huimin Cao, Yan Huang, Guangfu Xue, Huan Nie*, Qinghua Jiang*. Comprehensive Analysis of TCR Repertoire in COVID-19 using Single Cell Sequencing. 2020. Genomics. 2020 Dec 28; S0888-7543(20)32083-8. (SCI IF: 6.205)
Zhibin Lv# Pingping Wang#, Quan Zou*, Qinghua Jiang*. Identification of Sub-Golgi protein localization by use of deep representation learning features. Bioinformatics. 2020 Dec 26;btaa1074. (SCI IF: 5.61)
Xiaan Bi*, Yingchao Liu, Xi Hu, Qinghua Jiang*. Morbigenous brain region and gene detection with a genetically evolved random neural network cluster approach in late mild cognitive impairment. Bioinformatics. 2020 Apr 15;36(8):2561-2568. (SCI IF: 5.61)
Yan Huang#, Dianshuang Zhou#, Yihan Wang, Xingda Zhang, Mu Su, Cong Wang, Zhongyi Sun, Qinghua Jiang*, Baoqing Sun*,Yan Zhang*. Prediction of transcription factors binding events based on epigenetic modifications in different human cells. Epigenomics. 2020 Aug;12(16):1443-1456. (SCI IF: 4.112)
Wenyang Zhou#, Fan Yang#, Zhaochun Xu#, Meng Luo, Pingping Wang, Yu Guo, Huan Nie*, Lifen Yao*, Qinghua Jiang*. Comprehensive Analysis of Copy Number Variations in Kidney Cancer by Single-Cell Exome Sequencing. Front Genet. 2020 Jan 23;10:1379. (SCI IF: 3.258)
Nan Wang#, Jun Zhang#, Li Xu#, Jing Qi, Beibei Liu, Yiyang Tang, Yinan Jiang, Liang Cheng, Qinghua Jiang, Xunbo Yin, Shuilin Jin*. A novel estimator of between-study variance in random-effects models. BMC Genomics. 2020 Feb 11;21(1):149. (SCI IF: 3.594)
Qing Zhan, Yilei Fu, Qinghua Jiang, Bo Liu, Jiajie Peng, Yadong Wang*. SpliVert: A Protein Multiple Sequence Alignment Refinement Method Based on Splitting-Splicing Vertically. Protein Pept Lett. 2020;27(4):295-302. (SCI IF: 1.156)
Liran Juan*, Yongtian Wang, Jingyi Jiang, Qi Yang, Qinghua Jiang, Yadong Wang*. PGsim: A Comprehensive and Highly Customizable Personal Genome Simulator. Frontiers in Bioengineering and Biotechnology. 2020 Jan 28;8:28. (SCI IF: 3.644)
Tianjiao Zhang, Rongjie Wang, Qinghua Jiang*, Yadong Wang*. An information gain-based method for evaluating the classification power of features towards identifying enhancers. Current Bioinformatics. 2020. 15, 574-580. (SCI IF: 2.0)
Meng Luo#, Pingping Wang#, Liang Cheng#, Wenyang Zhou#, Yan Huang#, Lifen Yao#, Zhaochun Xu, Xiyun Jin, Chang Xu, Yuexin Yang, Rui Cheng, Peng Ren, Shuilin Jin, Guiyou Liu, Qinghua Jiang*, Yadong Wang*. SC2Cloud: Cloud-based data analysis platform for single-cell genome, transcriptome, epigenome and immunomics sequencing. (Submitted)
2019
Guiyou Liu, Yang Hu, Zhifa Han, Shuilin Jin*, Qinghua Jiang*. Genetic variant rs17185536 regulates SIM1 gene expression in human brain hypothalamus. PNAS. 2019 Feb 26;116(9):3347-3348. (SCI IF: 9.58)
Liang Cheng#, Pingping Wang#, Rui Tian#, Song Wang, Qinghua Guo, Meng Luo, Wenyang Zhou, Guiyou Liu, Huijie Jiang*, Qinghua Jiang*. LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in Human and Mouse. Nucleic Acids Research. 2019 Jan 8;47(D1):D140-D144 (SCI IF: 11.561)
Liang Cheng, Hengqiang Zhao, Pingping Wang, Wenyang Zhou, Meng Luo, Tianxin Li, Junwei Han*, Shulin Liu*, Qinghua Jiang*. Computational Methods for Identifying Similar Diseases. Mol Therapy Nucleic Acids. 2019 Dec 6; 18: 590–604. (SCI IF: 5.919)
Tao Wang#, Zhifa Han#, Rui Tian, Wenyang Zhou, Peng Ren, Pingping Wang, Jian Zong, Yang Hu, Qinghua Jiang*, The Alzheimer's Disease Neuroimaging Initiative§. Polygenic Risk Score for Alzheimer's Disease Is Associated with Ch4 Volume in Normal Subjects. Frontiers in Genetics. 2019 Jul 10;10:519. doi: 10.3389/fgene.2019.00519. (SCI IF: 4.151)
Yiqun Li, Ying Wu, Xiaohan Zhang, Yunfan Bai, Luqman Muhammad Akthar, Xin Lu, Ming Shi, Jianxiang Zhao, Qinghua Jiang*, Yu Li*. SCIA: an extensively applicable gene set analysis based on a novel permutation strategy. Frontiers in Genetics. 2019 Jun 25;10:598. doi: 10.3389/fgene.2019.00598. (SCI IF: 4.151)
Peng J, Hui W, Li Q, Chen B, Hao J, Jiang Q, Shang X, Wei Z. A learning-based framework for miRNA-disease association identification using neural networks. Bioinformatics. 2019 Apr 12. pii: btz254. doi: 10.1093/bioinformatics/btz254. (SCI IF: 4.53)
Xiaoyao Yang, Meng Luo, Qinghua Jiang*, Yiwei Wang*. Effects of Huangkui Capsule on the Expression of SPARC in the Kidney Tissue of a Rat Model with Diabetic Nephropathy. Current Gene Therapy. 2019;19(4):211-215. (SCI IF: 2.431)
Zhifa Han#, Tao Wang#, Rui Tian, Wenyang Zhou, Pingping Wang, Peng Ren, Jian Zong, Yang Hu, Shuilin Jin*, Qinghua Jiang*. BIN1 rs744373 variant shows different association with Alzheimer's disease in Caucasian and Asian populations. BMC Bioinformatics. 2019 Dec 24;20(Suppl 25):691. (SCI IF: 3.242)
Qing Zhan, Nan Wang, Shuilin Jin, Renjie Tan, Qinghua Jiang, Yadong Wang*. ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function. BMC Bioinformatics. 2019 Nov 25;20(Suppl 18):573. (SCI IF: 3.242)
2018
Guiyou Liu, Shuilin Jin, Yang Hu, Qinghua Jiang*. Disease status affects the association between rs4813620 and the expression of Alzheimer's disease susceptibility gene TRIB3. PNAS. 2018 Nov 6;115(45):E10519-E10520. (SCI, IF: 9.661)
Zhifa Han#, Rui Tian#, Peng Ren, Wenyang Zhou, Pingping Wang, Meng Luo, Shuilin Jin*, Qinghua Jiang*. Parkinson's disease and Alzheimer's disease: a Mendelian randomization study. BMC Medical Genetics. 2018 Dec 31;19(Suppl 1):215. (SCI IF: 1.585)
Liang Cheng#, Yang Hu#, Jie Sun, Meng Zhou*, and Qinghua Jiang*. DincRNA: a comprehensive web-based bioinformatics toolkit for exploring disease associations and ncRNA function. Bioinformatics. 2018 Jun 1;34(11):1953-1956. (SCI IF: 5.481)
Guiyou Liu, Yi Zhao, Shuilin Jin, Yang Hu, Tao Wang, Rui Tian, Zhifa Han, Dandan Xu, Qinghua Jiang*. Circulating vitamin E levels and Alzheimer's disease: a Mendelian randomization study. Neurobiol Aging. 2018 Aug 10. pii: S0197-4580(18)30291-4. (SCI, IF: 4.95)
Guiyou Liu, Yan Zhang, Longcai Wang, Jianyong Xu, Xiaoyun Chen, Yunjuan Bao, Yang Hu, Shuilin Jin, Rui Tian, Weiyang Bai, Wenyang Zhou, Tao Wang, Zhifa Han, Jian Zong, Qinghua Jiang*. Alzheimer's disease rs11767557 variant regulates EPHA1 gene expression specifically in human whole blood. Journal of Alzheimer's Disease. 2018, 61(3):1077-1088. (SCI, IF=3.731)
Guiyou Liu*,Tao Wang, Rui Tian, Yang Hu, Zhifa Han, Pingping Wang, Wenyang Zhou, Peng Ren, Jian Zong, Shuilin Jin*, Qinghua Jiang*. Alzheimer's Disease Risk Variant rs2373115 Regulates GAB2 and NARS2 Expression in Human Brain Tissues. Journal of Molecular Neuroscience. 2018 Sep;66(1):37-43. (SCI, IF: 2.37)
2017
Yang Hu, Shuilin Jin, Liang Cheng, Guiyou Liu*, Qinghua Jiang*. Autoimmune disease variants regulate GSDMB gene expression in human immune cells and whole blood. PNAS. 2017 Sep 19;114(38):E7860.(SCI IF: 9.661)
Guiyou Liu#, Yang Hu#, Shuilin Jin, Qinghua Jiang*. Genetic variant rs763361 regulates multiple sclerosis CD226 gene expression. PNAS. 2017 Feb 7;114(6):E906 (SCI IF: 9.661)
Qinghua Jiang#, Shuilin Jin#, Yongshuai Jiang, Mingzhi Liao, Rennan Feng,Liangcai Zhang, Guiyou Liu*, Junwei Hao*. Alzheimer's disease variants with the genome-wide significance are significantly enriched in immune pathways and active in immune cells. Molecular Neurobiology. 2017 Jan;54(1):594-600. (SCI, IF: 6.19)
Guiyou Liu#, Yining Xu#, Yongshuai Jiang, Mingzhi Liao, Rennan Feng, Qinghua Jiang*. PICALM rs3851179 variant confers susceptibility to Alzheimer's disease in Chinese population. Molecular Neurobiology.2017 Jul;54(5):3131-3136. (SCI, IF: 6.19)
Guiyou Liu#, Fang Zhang#, Yang Hu, Yongshuai Jiang, Zhongying Gong, Shoufeng Liu, Xiuju Chen, Qinghua Jiang*, Junwei Hao*. Genetic Variants and Multiple Sclerosis Risk Gene SLC9A9 Expression in Distinct Human Brain Regions. Molecular Neurobiology. 2017, 54(9):6820–6826 (SCI, IF: 6.19)
Guiyou Liu#, Fang Zhang#, Yongshuai Jiang, Yang Hu, Zhongying Gong, Shoufeng Liu, Xiuju Chen, Qinghua Jiang*, Junwei Hao*. Integrating genome-wide association studies and gene expression data highlights dysregulated multiple sclerosis risk pathways. Multiple Sclerosis. 2017 Feb;23(2):205-212. (SCI IF: 4.671)
Yang Hu#, Meng Zhou#, Hongbo Shi, Hong Ju, Qinghua Jiang*, Liang Cheng*. Measuring disease similarity and predicting disease-related ncRNAs by a novel method. BMC Medical Genomics. 2017,Dec 28,10(Suppl 5):71. (SCI IF: 2.848)
Guiyou Liu#, Fang Zhang#, Yang Hu, Yongshuai Jiang, Zhongying Gong, Shoufeng Liu, Xiuju Chen, Qinghua Jiang*, Junwei Hao*. Multiple sclerosis risk pathways differ in Caucasian and Chinese populations. Journal of Neuroimmunology. 2017 Jun 15;307:63-68. (SCI IF: 2.72)
Yang Hu#, Likun Zheng#, Liang Cheng, Ying Zhang, Weiyang Bai, Wenyang Zhou, Tao Wang, Zhifa Han, Jian Zong, Shuilin Jin, Jun Zhang*, Guiyou Liu*, Qinghua Jiang*. GAB2 rs2373115 variant contributes to Alzheimer's disease risk specifically in European population. Journal of Neurological Sciences. 2017 Apr 15;375:18-22. (SCI IF: 2.126)
Renjie Tan, Jixuan Wang, Xiaoliang Wu, Liran Juan, Likun Zheng, Rui Ma, Qing Zhan, Tao Wang, Shuilin Jin, Qinghua Jiang*, Yadong Wang*. ERDS-exome: a Hybrid Approach for Copy Number Variant Detection from Whole-exome Sequencing Data. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2017 Oct 4. doi: 10.1109/TCBB.2017.2758779. (SCI IF: 1.955)
Zhuo Wang#, Shuilin Jin#, Guiyou Liu, Xiurui Zhang, Nan Wang, Deliang Wu, Yang Hu, Chiping Zhang*, Qinghua Jiang*, Li Xu* and Yadong Wang*. DTWscore: differential expression and cell clustering analysis for time-series single-cell RNA-seq data. BMC Bioinformatics. 2017 May 23;18(1):270. (SCI IF: 2.448)
Xinwen Wang, Yiwen Cheng, Yifu Zhu, Huayi Li, Wenjie Ge, Xiaoliang Wu, Kunming Zhao, Jingyang Yuan, Zhenglin Li, Shijian Jiang, Zhengbin Han, Qinghua Jiang, Qiong Wu, Tao Liu, Cheng Zhang*, Miao Yu*, Ying Hu*. Epigenetic silencing of ASPP1 confers 5-FU resistance in clear cell renal cell carcinoma by preventing p53 activation. International Journal of Cancer. 2017 Oct 1;141(7):1422-1433. (SCI IF: 6.513)
Shuilin Jin*, Zhuo Wang, Junyu Lin, Jia Wang, Xiurui Zhang, Renjie Tan, Chuanbin Zhang, Zhe Wang, Wanqian Guo, Yang Hu, Li Xu, Lejun Zhang, Guiyou Liu, Qinghua Jiang, The complexity of promoter regions based on a vector topological entropy. Current Bioinformatics, 2017, 12(5): 471-474.（SCI, IF: 0.54）
2016
Guiyou Liu, Yang Hu, Shuilin Jin , Fang Zhang , Qinghua Jiang*, Junwei Hao*. cis-eQTLs regulate reduced LST1 and NCR3 expression and contribute to increased autoimmune disease risk. PNAS. 2016 Oct 18;113(42):E6321.(SCI IF: 9.423)
Guiyou Liu, Qinghua Jiang*. Alzheimer's disease CD33 rs3865444 variant does not contribute to cognitive performance. PNAS. 2016,113(12):E1589. (SCI IF: 9.423)
Qinghua Jiang, Guiyou Liu. REST rs3796529 variant does not influence human subcortical brain structures. Annals of Neurology. 2016 Feb;79(2):334-5. (SCI IF: 9.638)
Qinghua Jiang, Guiyou Liu. Lack of association between MC1R variants and Parkinson's disease in European descent. 2016. Annals of Neurology. DOI: 10.1002/ana.24627 (SCI IF: 9.638)
Tianjiao Zhang#, Yang Hu#, Xiaoliang Wu, Rui Ma, Qinghua Jiang*, Yadong Wang*.Identifying liver cancer-related enhancer SNPs by integrating GWAS and histone modification ChIP-seq data. BioMed Research International. 2016; 2016:2395341. doi: 10.1155/2016/2395341. Epub 2016 Jun 27. (SCI IF: 2.134)
Weiyang Bai, Wen Yang, Wenjing Wang, Yang Wang, Can Liu, Qinghua Jiang, Jinlian Hua, Mingzhi Liao*. GED: a manually curated comprehensive resource for epigenetic modification of gametogenesis. Briefings in Bioinformatics. 2016 Feb 5. pii: bbw007. (SCI, IF: 9.617)
Guoqiang Wan, Wenyang Zhou, Yang Hu, Rui Ma, Shuilin Jin, Guiyou Liu, Qinghua Jiang*. Transcriptional Regulation of lncRNA Genes by Histone Modification in Alzheimer's Disease. BioMed Research International. 2016;2016:3164238. (SCI IF: 2.134)
Li YN, Song DJ, Jiang YS, Wang J, Feng R, Zhang LC, Wang GY, Chen ZG, Wang RZ*, Jiang Qinghua*, Liu GY*. CR1 rs3818361 Polymorphism Contributes to Alzheimer's Disease Susceptibility in Chinese Population. Molecular Neurobiology. 2016 Aug;53(6):4054-4059. (SCI, IF: 5.137).
Zhang SY, Li X, Ma G, Jiang YS, Liao MZ, Feng RN, Zhang LC, Liu JF, Wang GY, Zhao B, Jiang Qinghua*, Li KS*, Liu GY*. CLU rs9331888 Polymorphism Contributes to Alzheimer's Disease Susceptibility in Caucasian But Not East Asian Populations. Molecular Neurobiology, 2016 Apr;53(3):1446-1451. (SCI, IF: 5.137)
Guiyou Liu, Yongquan Liu, Qinghua Jiang, Yongshuai Jiang, Rennan Feng, Liangcai Zhang, Zugen Chen, Keshen Li , Jiafeng Liu. Convergent Genetic and Expression Datasets Highlight TREM2 in Parkinson's Disease Susceptibility. Molecular Neurobiology. 2016, 53(7): 4931-4938. (SCI, IF: 5.137)
2015
Jiang QH, Wang JX, Wu XL, Ma R, Jin SL, Han ZJ, Tan RJ, Peng JJ, Liu GY, Li Y, Wang YD*. LncRNA2Target: a database for differentially expressed genes after lncRNA knockdown or overexpression. 2015. Nucleic Acids Research. 2015 Jan;43(Database issue):D193-6. (SCI, IF: 9.112)
Jiang QH, Ma R, Wang JX, Wu XL, Jin SL, Peng JJ, Tan RJ, Zhang TJ, Li Y, Wang YD*. LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data. 2015. BMC genomics. 16(s3):s2. (SCI, IF: 3.986)
Han ZJ, Jiang QH*, Zhang TJ, Wu XL, Ma R, Wang JX, Bai Y, Wang RJ, Tan RJ, Wang YD*. Analyzing large-scale samples confirms the association between the rs1051730 polymorphism and lung cancer susceptibility. 2015. Scientific Reports. (Accepted) (SCI, IF: 5.578)
Li YN, Song DJ, Jiang YS, Wang J, Feng R, Zhang LC, Wang GY, Chen ZG, Wang RZ*, Jiang QH*, Liu GY*. CR1 rs3818361 Polymorphism Contributes to Alzheimer's Disease Susceptibility in Chinese Population. Molecular Neurobiology. 2015 July 21. [Epub ahead of print]. (SCI, IF: 5.137)
Li KS, Jiang QH, Xu AD, Liu GY. REST rs3796529 variant does not confer susceptibility to Alzheimer's disease. Annals of Neurology. 2015 Aug 18. doi: 10.1002/ana.24503. [Epub ahead of print] (SCI IF: 9.638)
Bai Y, Ji SF, Jiang QH, Wang YD. Identification exon skipping events from high-throughput RNA sequencing data. IEEE Transactions on NanoBioscience. 2015 Jul;14(5):562-9 (SCI IF: 2.309)
Xinjie Bao, Gengfeng Chen, Yongshuai Jiang, Qinghua Jiang, Mingzhi Liao, Rennan Feng, Liangcai Zhang, Guoda Ma, Shuyan Zhang, Zugen Chen, Bin Zhao, Renzhi Wang*, Keshen Li*, Guiyou Liu*. Cell adhesion molecules pathways genes are regulated by cis-regulatory SNPs and show significantly altered expression in Alzheimer's disease brains. Neurobiol Aging. 2015 Jun 12 (SCI, IF: 5.013)
Xiao Zhu, Henry C.M. Leung, Rongjie Wang, Francis Y.L. Chin, Siu Ming Yiu, Guangri Quan, Yajie Li, Rui Zhang, Qinghua Jiang, Bo Liu, Yucui Dong, Guohui Zhou, Yadong Wang. misFinder: Identify mis-assemblies in an unbiased manner using reference and paired-end reads. BMC Bioinformatics. 2015 (Accepted) (SCI IF: 2.44)
Peng JJ, Li HX, Liu YZ, Juan LR, Jiang QH, Wang YD*. InteGO2: a web tool for measuring and visualizing gene semantic similarities using Gene Ontology. BMC Bioinformatics. 2015 (Accepted) (SCI, IF: 2.576)
Zhu X, Leung HC, Wang R, Chin FY, Yiu SM, Quan G, Li Y, Zhang R, Jiang Q, Liu B, Dong Y, Zhou G, Wang Y. misFinder: identify mis-assemblies in an unbiased manner using reference and paired-end reads. BMC Bioinformatics. 2015 Nov 16;16(1):386 (SCI, IF: 2.576)
2014
Jiang QH, Wang JX, Wang YD, Ma R, Wu XL, Li Y. TF2LncRNA: Identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data. BioMed Research International. vol. 2014, Article ID 317642, 5 pages, 2014. doi:10.1155/2014/317642 (SCI, IF: 2.706)
Quan BK, Qi XS, Yu ZH, Jiang YS, Liao MZ, Wang GY, Feng RN, Zhang LC, Chen ZG, Jiang QH*, Liu GY*. Pathway analysis of genome-wide association study and transcriptome data highlights new biological pathways in colorectal cancer. 2014. Molecular Genetics and Genomics. DOI 10.1007/s00438-014-0945-y. (SCI,IF: 2.831)
Liu GY, Bao XJ, Jiang Y,S Liao MZ, Jiang QH, Feng RN, Zhang LC, Ma GD, Chen ZG, Wang GY, Wang RZ, Zhao B, Li KS.Identifying the Association Between Alzheimer@#%s Disease and Parkinson@#%s Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network. 2014. Molecular Neurobiology. DOI 10.1007/s12035-014-8946-8 (SCI, IF=5.286)
Li X, Shen N, Zhang SY, Liu JF, Jiang QH, Liao MZ, Feng RN, Zhang LC, Wang GY, Ma GD, Zhou HH, Chen ZG, Jiang YS*, Zhao B*, Li KS*, Liu GY* (2014) CD33 rs3865444 polymorphism contributes to Alzheimer’s disease susceptibility in European and North American but not Asian populations. Molecular Neurobiology. DOI 10.1007/s12035-014-8880-9 (SCI, IF=5.286)
Xiang ZM, Xu ML, Liao MZ, Jiang YS, Jiang QH, Feng RN, Zhang LC, Ma GD, Wang GY, Chen ZG, Zhao B, Sun TS*, Li KS*, Liu GY* (2014) Integrating genome-wide association study and brain expression data highlights cell adhesion molecules and purine metabolism in Alzheimer’s disease. Molecular Neurobiology. DOI 10.1007/s12035-014-8884-5 (SCI, IF=5.286)
Peng JJ, Li HX, Jiang QH, Wang YD, Chen J. An Integrative Approach for Measuring Semantic Similarities using Gene Ontology. BMC systems biology. 2014, 8 (Suppl 5): S8 (SCI, IF: 2.853)
Tan RJ, Wang YD, Kleinstein S, Liu YZ, Zhu XL, Jiang QH, Zhu MF. An Evaluation of Copy Number Variation Detection Tools from Whole-Exome Sequencing Data. Human mutation. 2014 Mar 5. doi: 10.1002/humu.22537. [Epub 2014 May 1] (SCI, IF: 5.213)
Jin SL, Tan RJ, Jiang QH, Xu L, Peng JJ, Wang Y, Wang YD. A generalized topological entropy for analyzing the complexity of DNA sequences. PLoS One. 2014 Feb 12;9(2):e88519 (SCI, IF: 3.73)
2013
Qinghua Jiang, Guohua Wang, Shuilin Jin, Yu Li, Yadong Wang Predicting human microRNA-disease associations based on support vector machine, International Journal of Data Mining and Bioinformatics. 2013, 8(3): 282-293.
2012
Jin SL, Xu L, Jiang QH* and L Li*. Conditions equivalent to C* independence, Studia Mathematica. 211(3), 191-197, 2012 (SCI IF: 0.6)
Jin SL, Xu L, Jiang QH. Joint Spectrum and Joint Distribution. Complex analysis and operator theory. 2012. 7(6) 1869-1875 (SCI IF: 0.6)
Jin SL, Xu L, Jiang QH*, Duan GR. A Joint Spectral Characterization of C* Independence. Infinite Dimensional Analysis Quantum Probability and Related Topics. Vol. 15, No. 2 (2012) 1250013:1-5 （SCI IF: 0.57）
Jin SL, Jiang QH*, Wang YD*, Duan GR. On joint spectrum of infinite direct sums. Operators and Matrices. Vol. 6, No. 3 (2012), 529–533 （SCI IF: 0.435）
2011
Zhu SJ, Jiang QH, Wang GH, Liu B, Teng MX, Wang YD. Chromatin structure characteristics of pre-miRNA genomic sequences. BMC genomics.2011. 12(1):329. （SCI IF: 4.206）
2010
Jiang QH, Hao YY, Wang GH, Juan LR, Zhang TJ, Teng MX, Liu YL, Wang YD. Prioritization of disease microRNAs through a human phenome-microRNAome network, Bmc Systems Biology, 2010, 4 Suppl 1, S2. （SCI IF: 4.064）
2009
Jiang QH, Wang YD, Hao YY, Juan LR, Teng MX, Zhang XJ, Li MM, Wang GH, Liu YL. miR2Disease: a manually curated database for microRNA deregulation in human disease. Nucleic Acids Res．2009，37: D98-104 （SCI IF: 7.479）
国家科技创新2030“新一代人工智能”重大项目评审专家
国家重点研发计划重大项目会议评审专家
长江学者奖励计划评审专家
国家自然科学基金委员会信息学部、生命学部通讯评议专家
中国人工智能学会生物信息学与人工生命专委会常委
中国计算机学会生物信息学专业委员会常委
中国抗癌协会肿瘤标志专委会肿瘤测序及大数据分析协作组常委