个人简历

教育及学术经历\r
2011 - 现在: 副教授，博导 北京大学深圳研究生院\r
2008 -2010: 洪堡学者 柏林工业大学 (Technische Universität Berlin) 物理有机化学 导师: Prof. Dr. Drs. h.c. Helmut Schwarz\r
2002 - 2007: 博士 香港科技大学 理论有机化学 导师: 吴云东 院士\r
1998 - 2002: 学士（化学） 中国科学技术大学\r
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获奖情况\r
2012: 深圳市海外高层次人才\r
2012： 深圳市高层次人才—地方领军人才\r
2008 - 2010: 亚历山大∙冯∙洪堡奖学金\r
1999 - 2001: 中国科大优秀奖学金\r
1999: 可口可乐杯——中国科大第10届辩论赛冠军

研究领域

"""""结合质谱与计算化学方法于\r
理解各类催化反应机理及筛选新催化剂\r
建立金属离子-生物小分子结合能的数据库并发展新的无机力场和过渡态力场\r
研究蛋白质-配体相互作用及设计新型无机药物\r
开发气相中的手性分子识别"

近期论文

Gui-Juan Cheng, Li-Juan Song, Yun-Fang Yang, Xinhao Zhang,* Olaf Wiest,* Yun-Dong Wu,* “Computational Studies on the Mechanism of the Copper-Catalyzed sp3-C-H Cross- Dehydrogenative Coupling Reaction” ChemPlusChem 2013, 78, 943-951.\r
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Lizhi Zhu, Chongshan Zhou, Wei Yang, Shuzhong He, Gui-Juan Cheng, Xinhao Zhang,* Chi-Sing Lee,* “Formal Syntheses of (±)-Platensimycin and (±)-Platencin via a Dual-Mode Lewis Acid Induced Cascade Cyclization Approach.” J. Org. Chem. 2013, 78, 7912-7929.\r
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Shengtao Ding, Li-Juan Song, Lung Wa Chung, Xinhao Zhang, Jianwei Sun, Yun-Dong Wu, Ligand-Controlled Remarkable Regio- and Stereodivergence in Intermolecular Hydrosilylation of Internal Alkynes: Experimental and Theoretical Studies. J. Am. Chem. Soc. 2013, 135, 13835-13842.\r
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Yun-Fang Yang, Gui-Juan Cheng, Peng Liu, Dasheng Leow, Tian-Yu Sun, Ping Chen, Xinhao Zhang, Jin-Quan Yu,* Yun-Dong Wu,* Ken N. Houk,* Palladium-Catalyzed meta-Selective C–H Bond Activation with a Nitrile-Containing Template: A Computational Study on Mechanism and Origins of Selectivity J. Am. Chem. Soc. 2014, 136, 344-355.\r
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Gui-Juan Cheng, Yun-Fang Yang, Peng Liu, Ping Chen, Tian-Yu Sun, Gang Li, Xinhao Zhang, Ken N. Houk,* Jin-Quan Yu,* Yun-Dong Wu,* Role of N-Acyl Amino Acid Ligands in Pd(II)-Catalyzed Remote C–H Activation of Tethered Arenes J. Am. Chem. Soc. 2014, 136, 894-897.\r
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Liping Xu, Margaret J. Hilton, Xinhao Zhang, Per-Ola Norrby,* Yun-Dong Wu,* Matthew S. Sigman,* Olaf Wiest,* Mechanism, Reactivity, and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols J. Am. Chem. Soc. 2014, 136, 1960-1967.\r
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Pingping Duan, Yunfang Yang, Rong Ben, Yiyong Yan, Lu Dai, Mei Hong, Yun-Dong Wu, Dongqi Wang,* Xinhao Zhang,* Jing Zhao,* Palladium-catalyzed benzo[d]isoxazole synthesis by C-H activation/[4 + 1] annulations. Chem. Sci. 2014, 5, 1574-1578.\r
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Fengtao Zhou, Gui-Juan Cheng, Wenqiang Yang, Yan Long, Shasha Zhang, Yun-Dong Wu, Xinhao Zhang,* Qian Cai* Enantioselective Formation of Cyano-Bearing All-Carbon Quaternary Stereocenters: Desymmetrization by Copper-Catalyzed N-Arylation. Angew. Chem. Int. Ed. 2014, 53, 9555-9559.\r
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Huan Sun , Chengming Wang , Yun-Fang Yang , Ping Chen , Yun-Dong Wu *, Xinhao Zhang *, Yong Huang * Synthesis of Indolo[2,1-a]isoquinolines via a Triazene-Directed C–H Annulation Cascade J. Org. Chem. 2014, 79, 11863-11872\r
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Yun-Fang Yang, Lung Wa Chung, Xinhao Zhang, K.N. Houk,* Yun-Dong Wu,* Ligand-Controlled Reactivity, Selectivity, and Mechanism of Cationic Ruthenium-Catalyzed Hydrosilylations of Alkynes, Ketones, and Nitriles: A Theoretical Study, J. Org. Chem. 2014, 79, 8856-8864.\r
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Gui-Juan Cheng, Xinhao Zhang, Lung Wa Chung, Liping Xu, Yun-Dong Wu,* Computational Organic Chemistry: Bridging Theory and Experiment in Establishing the Mechanisms of Chemical Reactions, J. Am. Chem. Soc. 2015, 137, 1706-1725\r
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Jialing Shi, Ting Wang, Yusha Huang, Xinhao Zhang,* Yun-Dong Wu,* Qian Cai,* Pd-Catalyzed Asymmetric Intramolecular Aryl C–O Bond Formation with SDP(O) Ligand: Enantioselective Synthesis of (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methanols, Org. Lett. 2015, 17, 840-843.\r
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Shengtao Ding, Li-Juan Song, Yong Wang, Xinhao Zhang,* Lung Wa Chung,* Yun-Dong Wu,* Jianwei Sun,* Highly Regio- and Stereoselective Hydrosilylation of Internal Thioalkynes under Mild Conditions Angew. Chem. Int. Ed. 2015, 54, 5632-5635\r
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Gui-Juan Cheng, Ping Chen, Tian-Yu Sun, Xinhao Zhang,* Jin-Quan. Yu,* Yun-Dong Wu,* A Combined IM-MS/DFT Study on [Pd(MPAA)]-Catalyzed Enantioselective C-H Activation: Relay of Chirality through a Rigid Framework Chem. Eur. J., 2015, 21, 11180-11188\r
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Yong-Hui Sun, Tian-Yu Sun, Yun-Dong Wu, Xinhao Zhang,* Yu Rao,* A diversity-oriented synthesis of bioactive benzanilides via a regioselective C(sp2)-H hydroxylation strategy. Chem. Sci.2016, 7, 2229-2238\r
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Tian-Yu Sun, Xiao Wang, Hao Geng, Yaoming Xie, Yun-Dong Wu, Xinhao Zhang,* Henry F. Schaefer III,* Why does Togni's reagent I exist in the high-energy hypervalent iodine form? Re-evaluation of benziodoxole based hypervalent iodine reagents. Chem. Commun. 2016, 52, 5371-5374\r
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Le Liu, Tonghuan Zhang, Yun-Fang Yang, Daisy Zhang-Negrerie, Xinhao Zhang, Yunfei Du,* Yun-Dong Wu,* Kang Zhao,* Metal-Free Synthesis of 3-Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study. J. Org. Chem. 2016, 81, 4058-4065\r
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Xinhao Zhang,* Lung Wa Chung,* Yun-Dong Wu,* New Mechanistic Insights on the Selectivity of Transition-Metal-Catalyzed Organic Reactions: The Role of Computational Chemistry. Acc. Chem. Res. 2016, 49, 1302-1310\r
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Huan Sun, Yi Zhang, Ping Chen, Yun-Dong Wu,* Xinhao Zhang,* Yong Huang,* Ligand-Assisted Palladium(II)/(IV) Oxidation for sp3 C-H Fluorination. Adv. Synth. Catal. 2016, 358 (12), 1946-1957\r
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Li-Juan Song, Shengtao Ding, Yong Wang, Xinhao Zhang,* Yun-Dong Wu,* Jianwei Sun,* Ir-Catalyzed Regio- and Stereoselective Hydrosilylation of Internal Thioalkynes: A Combined Experimental and Computational Study. J. Org. Chem. 2016, ASAP, DOI: 10.1021/acs.joc.6b00854