近期论文
Carroni, Marta and Saibil, Helen R. (2016) Cryo electron microscopy to determine the structure of macromolecular complexes. Methods 95 , pp. 78-85. ISSN 1046-2023.Watermeyer, Jean M. and Hale, Victoria L. and Hackett, F. and Clare, Daniel K. and Cutts, E.E. and Vakonakis, I. and Fleck, R.A. and Blackman, M.J. and Saibil, Helen R. (2016) A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes. Blood 127 (3), pp. 343-351. ISSN 0006-4971.Nans, Andrea and Kudryashev, M. and Saibil, Helen R. and Hayward, Richard (2015) Structure of a bacterial type III secretion system in contact with a host membrane in situ. Nature Communications 6 , p. 1104. ISSN 2041-1723.Das, S. and Hertrich, N. and Perrin, A.J. and Withers-Martinez, C. and Collins, C.R. and Jones, M.L. and Watermeyer, Jean M. and Fobes, E.T. and Martin, S.R. and Saibil, Helen R. and Wright, G.J. and Treeck, M. and Epp, C. and Blackman, M.J. (2015) Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 activates a Spectrin-binding function enabling parasite egress from RBCs. Cell Host & Microbe 18 (4), pp. 433-444. ISSN 1931-3128.O'Driscoll, Jonathan and Clare, Daniel K. and Saibil, Helen R. (2015) Prion aggregate structure in yeast cells is determined by the Hsp104-Hsp110 disaggregase machinery. The Journal of Cell Biology 211 (1), pp. 145-158. ISSN 0021-9525.Gao, X. and Carroni, Marta and Nussbaum-Krammer, C. and Mogk, A. and Nillegoda, N.B. and Szlachcic, A. and Guilbride, D.L. and Saibil, Helen R. and Mayer, M.P. and Bukau, B. (2015) Human Hsp70 Disaggregase reverses Parkinson’s-linked α-Synuclein Amyloid Fibrils. Molecular Cell 59 (5), pp. 781-793. ISSN 1097-2765.Sali, A. and Berman, H.M. and Schwede, T. and Trewhella, J. and Kleywegt, G. and Burley, S.K. and Markley, J. and Nakamura, H. and Adams, P. and Bonvin, A.M.J.J. and Wah, C. and Dal Peraro, M. and Di Maio, F. and Ferrin, T.E. and Grünewald, K. and Gutmanas, A. and Henderson, R. and Hummer, G. and Iawsaki, K. and Johnson , G. and Lawson, C.L. and Meiler, J. and Marti-Renom, M.A. and Montelione, G.T. and Nilges, M. and Nussinov, R. and Patwardhan, A. and Rappsilber, J. and Read, R.J. and Saibil, Helen R. and Schröder, G.F. and Schwieters, C. and Seidel, C.A.M. and Svergun, D. and Topf, Maya and Ulrich, E.L. and Velankar, S. and Westbrook, J.D. (2015) Outcome of the First wwPDB Hybrid / Integrative Methods Task Force Workshop. Structure 23 (7), pp. 1156-1167. ISSN 0969-2126.Wenborn, A. and Terry, C. and Gros, N. and Joiner, S. and D’Castro, L. and Panico, Silvia and Sells, J. and Cronier, S. and Linehan, J.M. and Brandner, S. and Saibil, Helen R. and Collinge, J. and Wadsworth, J.D.F. (2015) A novel and rapid method for obtaining high titre intact prion strains from mammalian brain. Scientific Reports 5 , p. 10062. ISSN 2045-2322.Lukoyanova, Natalya and Kondos, S.C. and Farabella, Irene and Law, R.H.P. and Reboul, C.F. and Caradoc-Davies, T.T. and Spicer, B.A. and Kleifeld, O. and Traore, D.A.K. and Ekkel, S.M. and Voskoboinik, I. and Trapani, J.A. and Hatfaludi, T. and Oliver, K. and Hotze, E.M. and Tweten, R.K. and Whisstock, J.C. and Topf, Maya and Saibil, Helen R. and Dunstone, M.A. (2015) Conformational changes during pore formation by the perforin-related protein pleurotolysin. PLOS Biology 13 (2), e1002049. ISSN 1545-7885.Dumoux, Maud and Nans, Andrea and Saibil, Helen R. and Hayward, Richard (2015) Making connections: snapshots of chlamydial type III secretion systems in contact with host membranes. Current Opinion in Microbiology 23 , pp. 1-7. ISSN 1369-5274.Saibil, Helen R. and Grünewald, K. and Stuart, D.I. (2015) A national facility for biological cryo-electron microscopy. Acta Crystallographica Section D Biological Crystallography 71 (1), pp. 127-135. ISSN 0907-4449.Leung, C. and Dudkina, N.V. and Lukoyanova, Natalya and Hodel, A.W. and Farabella, I. and Pandurangan, A.P. and Jahan, N. and Pires Damaso, M. and Osmanović, D. and Reboul, C.F. and Dunstone, M.A. and Andrew, P.W. and Lonnen, R. and Topf, Maya and Saibil, Helen R. and Hoogenboom, B.W. (2014) Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin. eLife 3 , ISSN 2050-084X.Patwardhan, A. and Ashton, A. and Brandt, R. and Butcher, S. and Carzaniga, R. and Chiu, W. and Collinson, L. and Doux, P. and Duke, E. and Ellisman, M.H. and Franken, E. and Grünewald, K. and Heriche, J.-K. and Koster, A. and Kühlbrandt, W. and Lagerstedt, I. and Larabell, C. and Lawson, C.L. and Saibil, Helen R. and Sanz-García, E. and Subramaniam, S. and Verkade, P. and Swedlow, J.R. and Kleywegt, G.J. (2014) A 3D cellular context for the macromolecular world. Nature Structural & Molecular Biology 21 (10), pp. 841-845. ISSN 1545-9993.Nans, Andrea and Saibil, Helen R. and Hayward, Richard (2014) Pathogen-host reorganisation during Chlamydia invasion revealed by cryo-electron tomography. Cellular Microbiology 16 (10), pp. 1457-1472. ISSN 1462-5814.Nans, Andrea and Saibil, Helen R. and Hayward, Richard (2014) Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography. Cellular Microbiology 16 (10), pp. 1457-1472. ISSN 1462-5814.Trevitt, C.R. and Hosszu, L.L.P. and Batchelor, M. and Panico, S. and Terry, C. and Nicoll, A.J. and Risse, E. and Taylor, W.A. and Sandberg, M.K. and Al-Doujaily, H. and Linehan, J.M. and Saibil, Helen R. and Scott, D.J. and Collinge, J. and Waltho, J.P. and Clarke, A.R. (2014) N-terminal domain of Prion Protein directs its Oligomeric Association. Journal of Biological Chemistry 289 , pp. 25497-25508. ISSN 0021-9258.Carroni, Marta and Kummer, E. and Oguchi, Y. and Wendler, P. and Clare, Daniel K. and Sinning, I. and Kopp, J. and Mogk, A. and Bukau, B. and Saibil, Helen R. (2014) Head-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregation. eLife 3 , e02481-e02481. ISSN 2050-084X.Carroni, M. and Kummer, E. and Oguchi, Y. and Wendler, P. and Clare, D.K. and Sinning, I. and Kopp, J. and Mogk, A. and Bukau, B. and Saibil, Helen R. (2014) Head-to-tail interactions of the coiled-coil domains regulate ClpB cooperation with Hsp70 in protein disaggregation. eLife , ISSN 2050-084X.Clare, Daniel K. and Saibil, Helen R. (2013) ATP-driven molecular chaperone machines. Biopolymers 99 (11), pp. 846-859. ISSN 0006-3525.Saibil, Helen R. (2013) Chaperone machines for protein folding, unfolding and disaggregation. Nature Reviews Molecular Cell Biology 14 (10), pp. 630-642. ISSN 1471-0072.Housden, N.G. and Hopper, J.T.S. and Lukoyanova, Natalya and Rodriguez-Larrea, D. and Wojdyla, J.A. and Klein, A. and Kaminska, R. and Bayley, H. and Saibil, Helen R. and Robinson, C.V. and Kleanthous, C. (2013) Intrinsically disordered protein threads through the bacterial outer-membrane Porin OmpF. Science 340 (6140), pp. 1570-1574. ISSN 0036-8075.Saibil, Helen R. and Fenton, W. and Clare, Daniel K. and Horwich, A.L. (2013) Structure and allostery of the Chaperonin GroEL. Journal of Molecular Biology 425 (9), pp. 1476-1487. ISSN 0022-2836.Lopez, J.A. and Susanto, O. and Jenkins, M.R. and Lukoyanova, Natalya and Sutton, V.R. and Law, R.H.P. and Johnston, A. and Bird, C.H. and Bird, P I. and Whisstock, J.C. and Trapani, J.A. and Saibil, Helen R. and Voskoboinik, I. (2013) Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 121 (14), pp. 2659-2668. ISSN 0006-4971.Saibil, Helen R. (2013) Machinery to reverse irreversible aggregates. Science 339 (6123), pp. 1040-1041. ISSN 0036-8075.Dumoux, Maud and Clare, Daniel K. and Saibil, Helen R. and Hayward, Richard (2012) Chlamydiae assemble a pathogen synapse to hijack the host endoplasmic reticulum. Traffic 13 (12), pp. 1612-1617. ISSN 1398-9219.
