个人简历

2019-至今，北京师范大学化学学院，教授\r
2016-2018 年，美国University of Florida，博士后（导师：谭蔚泓教授）\r
2010-2016 年，美国University of Massachusetts Amherst，博士 （导师：Vincent M. Rotello教授）

研究领域

"""""分析化学；脑神经分析化学；纳米生物化学；化学生物学\r
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本课题组将主要围绕脑神经分析化学领域展开工作。以活动物脑内神经化学信号分子为对象，通过创新分析化学原理和方法，实现对于神经生理和病理过程中神经化学信号的精准测量\r
主要包括以下三方面工作\r
1）构建具有高选择性和高稳定性的活体识别元件\r
2）发展多通道活体分析方法\r
3）探索神经信号分子在大脑活动尤其是神经退行性疾病过程的作用机制"

近期论文

Xiao, T.; Wang, Y.; Wei, H.; Yu, P.; Jiang, Y.;* and Mao, L.* Electrochemical Monitoring of Propagative Fluctuation of Ascorbate in the Live Rat Brain during Spreading Depolarization, Angew. Chem. Int. Ed., 2019, 58, 6616–6619. .\r
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Liang, C.; Chang, J.; Jiang, Y.;*, Liu, J.; Mao, L.; and Wang, M.* Selective RNA Interference and Gene Silencing using Reactive Oxygen Species-responsive Lipid Nanoparticles, Chem. Commun., 2019, 55, 8170-8173.\r
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Jiang, Y,; Pan, X.; Chang, J.; Niu, W. J.; Hou, W. J.; Kuai, H.; Zhao, Z.; Liu, J.; Wang, M.; and Tan, W. Supramolecularly Engineered Circular Bivalent Aptamer for Enhanced Functional Protein Delivery, J. Am. Chem. Soc., 2018, 140, 6780-6784.\r
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Jiang, Y.; Shi, M.; Liu, Y.; Wan, S.; Cui, C.; Zhang, L.; and Tan, W. Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins, Angew. Chem. Int. Ed., 2017, 56, 11916-11920.\r
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Jiang, Y.; Tang, R.; Duncan, B.; Jiang, Z. W.; Yan, B.; Mout, R.; and Rotello, V. M. Direct Cytosolic Delivery of siRNA Using Nanoparticle Stabilized Nanocapsules, Angew. Chem. Int. Ed., 2015, 54, 506-510.\r
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Jiang, Y.; Zhao, H.; Lin, Y.; Yu, P.; and Mao, L. Colorimetric Detection of Glucose in Rat Brain Using Gold Nanoparticles, Angew. Chem. Int. Ed., 2010, 49, 4800-4804. \r
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Jiang, Y.; Zhao, H.; Zhu, N. N.; Lin, Y.; Yu, P.; and Mao, L. A Simple Assay for Direct Colorimetric Visualization of Trinitrotoluene at Picomolar Levels Using Gold Nanoparticles, Angew. Chem. Int. Ed., 2008, 47, 8601-8604. \r
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Jiang, Y.; Huo, S. D.; Mizuhara, T.; Das, R.; Lee, Y. L.; Hou, S.; Moyano, D. F.; Duncan, B.; Liang, X. J.; and Rotello, V. M. The Interplay of Size and Surface Functionality on the Cellular Uptake of Sub-10 nm Gold Nanoparticles, ACS Nano 2015, 9, 9986-9993.\r
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Jiang, Y.; Wang, M.; Hardie, J.; Tonga, G. Y.; Ray, M.; Xu, Q. B.; and Rotello, V. M. Chemically Engineered Nanoparticle-Protein Interface for Real Time Cellular Oxidative Stress Monitoring, Small 2016, 12, 3775-3779.\r
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Zhao, L.; † Jiang, Y.; † Wei, H.; Jiang, Y.; Ma, W.; Zheng, W.; Cao, A. M.; and Mao, L. In Vivo Measurement of Calcium Ion with Solid-State Ion-Selective Electrode by Using Shelled Hollow Carbon Nanospheres as Transducing Layer, Anal. Chem., 2019, 91, 4421-4428. (†Equal contribution)