个人简历

主要教育经历\r
1991 加拿大麦吉尔大学 (McGill University)，化学工程系及临床研究所，生物医学工程专业博士\r
1982 成都科技大学，工程力学系，生物力学专业硕士 \r
1975 武汉华中理工大学，火电站专业本科专业\r
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主要工作经历\r
2008—至今 北京航空航天大学生物与医学工程学院 教授，博导\r
2005—2008 北京航空航天大学生物工程系 教授，博导，\r
2002—2004 重庆大学生物工程学院 教授，博导，院长\r
2000—2002 大连理工大学工程力学系 教授，博导\r
1995—2000 加拿大魁北克拉瓦尔大学生物材料研究所 研究员\r
加拿大魁北克拉瓦尔大学医学院外科系 科研教授\r
1991—1995 加拿大魁北克拉瓦尔大学生物材料研究所 博士后\r
1983—1985 成都科技大学 （现四川大学） 工程力学系 助教\r
1978—1980 四川省环境保护研究所 助理工程师\r
1975—1978 西南核反应堆研究设计院（二机部第一设计院） 反应堆操纵员

研究领域

血流动力学\r
心血管介入器械与人工器官\r
细胞生物力学与力生物学""

近期论文

Fan Z, Liu X, Du C, et al. Plaque components affect wall stress in stented human carotid artery: a numerical study[J]. Acta Mechanica Sinica, 2016: (ahead of print).\r
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Hongyan Kang, Lianwen Sun, Yunfei Huang, Zhenze Wang, Ping Zhao,Yubo Fan,Xiaoyan Deng. Regional specific adaptation of the endothelial glycocalyx dimension in tail-suspended rats. Pflugers Arch - Eur J Physiol (2015) 467:1291–1301\r
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Anqiang Sun, Zhenze Wang, Zhenmin Fan, Xiaopeng Tian, Fan Zhan, Xiaoyan Deng,Xiao Liu. Influence of proximal drug eluting stent (DES) on distal bare metal stent (BMS) in multi-stent implantation strategies in coronary arteries. Medical Engineering and Physics 37 (2015) 840–844.\r
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Xiao Liu, Min Wang, Nan Zhang, Zhanming Fan, Yubo Fan,Xiaoyan Deng. Effects of endothelium, stent design and deployment on the nitric oxide transport in stented artery: a potential role in stent restenosis and thrombosis. Med Biol Eng Comput (2015) 53:427–439\r
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Xue Yan, Liu Xiao, Sun Anqiang, Zhang Peng, Fan Yubo, Deng Xiaoyan . Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study[J]. Artificial Organs, 2015.\r
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Sun Anqiang , Tian Xiaopeng, Zhang Nan, Xu Zaipin, Deng Xiaoyan, Liu Ming and Liu Xiao. Does lower limb exercise worsen renal artery hemodynamics in patients with abdominal aortic aneurysm?[J]. PloS one, 2015, 10(5).\r
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Zhang P, Liu X, Sun AQ, Deng XY. Hemodynamic insight into overlapping bare-metal stents strategy in the treatment of aortic aneurysm. J Biomech. 2015, 48:2041-2046.\r
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Liu X, Sun AQ, Fan YB, Deng XY. Physiological Significance of Helical Flow in the Arterial System and its Potential Clinical Applications. Ann Biomed Eng. 43(4):3-15 (2015)\r
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Sun AQ, Wang ZZ, Zhan F, Xu ZP, Deng XY. A New Way to Optimize Drug Release Rate of Drug Eluting Stent (Des). Journal of Mechanics in Medicine and Biology. 2015: 1550064.\r
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Chen ZS, Zhan, F, Ding J, Zhang XW, Deng XY. A new stent with streamlined cross-section can suppress monocyte cell adhesion in the flow disturbance zones of the endovascular stent. Comput Methods Biomech Biomed Engin. (2014，online)\r
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Wang ZZ, Liu X, Kang HY, Sun AQ, Fan YB, Deng XY. Effect of shear stress on water and LDL transport through cultured endothelial cellmonolayers Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate mayaccount for its accelerated atherogenesis. Atherosclerosis 236(1):198-206 (2014)\r
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Zhang P, Sun AQ, Zhan F, Luan J, Deng XY. Hemodynamic study of overlapping bare-metal stents intervention to aortic aneurysm. J Biomech. 47(14):3524-30 (2014)\r
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Liu X, Wang ZZ, Zhao P, Fan ZM, Sun AQ, Zhan F, Fan YB, Deng XY. Nitric oxide transport in normal human thoracic aorta: effects of hemodynamics and nitricoxide scavengers. PLoS One 9(11):e112395(2014)\r
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Kang HY, Sun LW, Huang YF, Wang ZZ, Zhao P, Fan YB, Deng XY. Regional specific adaptation of the endothelial glycocalyx dimension in tail-suspended rats. Pflugers Arch. DOI: 10.1007/s00424-014-1568-1 (2014)\r
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Kang HY, Liu ML, Fan YB, Deng XY. A potential gravity-sensing role of vascular smooth muscle cell glycocalyx in altered gravitational stimulation. Astrobiology 13(7):626-36 (2013)\r
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Liu X, Fan YB, Sun AQ, Deng XY. Numerical simulation of nucleotide transport in the human thoracic aorta. J Biomech. 46(4):819-27 (2013)\r
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Fan ZM, Sun AQ, Liu X, Fan YB, Zhao P, Deng XY.The accelerated atherogenesis of venous grafts might be attributed to aggravated concentration polarization of low density lipoproteins: A numerical study. J Biomech 46(14):2388-93 (2013)\r
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Kang HY, Fan YB, Sun AQ, Jia XL, Deng XY. Simulated Microgravity Exposure Modulates the Phenotype of Cultured Vascular Smooth Muscle Cells. Cell Biochem Biophys. 66(1):121-30 (2013)\r
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Sun AQ, Fan YB, Deng XY. Intentionally induced swirling flow may improve the hemodynamic performance of coronary bifurcation stenting. Catheterization and Cardiovascular Interventions 79:371–377 (2012)\r
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Ding ZF, Liu SJ, Yang B, Fan YB, Deng XY. Effect of oxidized low-density lipoprotein concentration polarization on human smooth muscle cells' proliferation, cycle, apoptosis and oxidized low-density lipoprotein uptake. Journal of the Royal Society Interface. 2012 Jun; 9(71):1233-40.\r
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Zhan F, Fan YB, Deng XY. Effect of swirling flow on platelet concentration distribution in small-caliber artificial grafts and end- to- end anostomoses. Acta Mechanica Sinica 2011;27 (5):833-839.\r
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Liu X, Fan YB, Deng XY, Zhan F. Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta. Journal of Biomechanics 2011;44:1123-1131.\r
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Liu X, Fan YB, Deng XY. Effect of the endothelial glycocalyx layer on arterial LDL transport under normal and high pressure. Journal of Theoretical Biology 2011;283(1):71-81.\r
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Liu X, Fan YB, Deng XY. Mechanotransduction of Flow-Induced Shear Stress by Endothelial Glycocalyx Fibers is Torque Determined. ASAIO Journal 2011;57(6):487-94.\r
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Chen ZS, Fan YB, Deng XY. A novel deployment design of vena cava filters might be the solution to their blockage problem. Medical Hypotheses 2011;77(6):990-2.\r
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Chen ZS, Fan YB, Deng XY, Zhai XP. A New Way to Reduce Flow Disturbance in Endovascular Stents: A Numerical Study. Artificial Organs 2011;35(4):392-7.\r
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Chen ZS, Fan Z, Fan YB, Deng XY. A novel way to reduce thrombus build-up in vena cava filters. Catheterization and Cardiovascular Interventions 2011;78(5):792-8.\r
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Kang HY, Fan YB, Deng XY. Vascular smooth muscle cell glycocalyx modulates shear-induced proliferation, migration and NO production responses. Am J Physiol Heart Circ Physiol 2011;300(1):H76-83.\r
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Kang HY, Fan YB, Sun AQ, Deng XY. Compositional or charge density modification of the endothelial glycocalyx accelerates flow-dependent concentration polarization of low-density lipoproteins. Experimental Biology and Medicine 2011;236(7):800-7.\r
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Zhou J, Lin J, Zhou CH, Deng XY, Xia B. Cytotoxicity of red fluorescent protein DsRed is associated with the suppression of Bcl-xL translation. FEBS Letters 2011;585:821-827.\r
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Zhou J, Lin J, Zhou CH, Deng XY, Xia B. An improved bimolecular fluorescence complementation (BiFC) tool based on super-folder GFP. Acta Biochimica et Biophysica Sinica 2011;43: 239–244.\r
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Wen J, Zheng TH, Jiang WT, Deng XY, Fan YB. A comparative study of helical-type and traditional-type artery bypass grafts: numerical simulation. ASAIO Journal 2011;57(5):399-406\r
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Liu X, Fan YB, Deng XY. Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Ann Biomed Eng 2010;38(3):917-926.\r
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Sun AQ, Fan YB, Deng XY. Numerical comparative study on the hemodynamic performance of a new helical graft with noncircular cross section and swirl graft. Artificial organs 2010;34(1):22-27\r
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Sun AQ, Fan YB, Deng XY, Xu ZP. Hemodynamic performance of a sutureless anastomosis device (the Graft Connector): A numerical study. International Journal of Artificial Organs 2010;33(6):392-398\r
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Ding ZF, Fan YB, Deng XY. Concentration polarization of oxidative modification of low-density lipoproteins: its effect on oxidative modification of low-density lipoprotein uptake and apoptosis of the endothelial cells. ASAIO JOURNAL 2010;56(5):468-474\r
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Ding ZF, Fan YB, Deng XY, Zhan F, Kang HY. Effect of swirling flow on the uptakes of native and oxidized LDLs in a straight segment of the rabbit thoracic aorta. Experimental Biology and Medicine 2010;235:506-513\r
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Ding ZF, Fan YB, Deng XY, Sun AQ, Kang HY. 3,3 '-Dioctadecylindocarbocyanine-low-density lipoprotein uptake and flow patterns in the rabbit aorta-iliac bifurcation under three perfusion flow conditions. Experimental Biology and Medicine 2010;235:506-513\r
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Zhan F, Fan YB, Deng XY, Xu ZP. The beneficial effect of swirling flow on platelet adhesion to the surface of a sudden tubular expansion tube: its potential application in end-to-end arterial anastomosis. ASAIO J 2010;56(3):172-179\r
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Zhan F, Fan YB, Deng XY. Swirling flow created in a glass tube suppressed platelet adhesion to the surface of the tube: its implication in the design of small-caliber arterial grafts. Thrombosis Research 2010;125(5):413-418
中国生物医学工程学会(第六届) 理事
中国生物物理学会生物力学及生物流变学专业委员会 委员
生物力学专业委员会(第五届) 副主任
生物力学专业委员会(第六届) 委员
《生物物理学报》 编委
《医用生物力学》 编委
《生物医学工程学杂志》 编委
《力学学报》（英文版） 编委