研究领域

一直从事生物体内重要蛋白质的修饰及其在发病中的作用机理的研究

近期论文

1. Wang Y, Zhang N, Zhang L, Li R, Fu W, Ma K, Li X, Wang L, Wang J, Zhang H, Gu W, Zhu WG*, Zhao Y*. Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62. Mol Cell. 2016 Jun 21.
2. Zhang N, Yang X, Yuan F, Zhang L, Wang Y, Wang L, Mao Z, Luo J, Zhang H, Zhu WG, Zhao Y*. Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine Deprivation. Cell Rep. 2018 Jun 5;23(10):3006-3020.
3. Li R, Yuan F, Fu W, Zhang L, Zhang N, Wang Y, Ma K, Li X, Wang L, Zhu WG, Zhao Y*. Serine/threonine Kinase Unc-51 Like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cdc37 and Thereby Disrupts the Stability of Cdc37 Client Proteins. J Biol Chem. 2017 Feb 17;292(7):2830-2841.
4. Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S, Wang D, Feng J, Yu L, Zhu WG Cytosolic FoxO1 is essential for the induction of autophagy and tumor suppressor activity Nature Cell Biology, 2010 Jul;12(7):665-75.
5. Zhao Y（共同责任作者）, Li X, Cai MY, Ma K, Yang J, Zhou J, Fu W, Wei FZ, Wang L, Xie D, Zhu WG. XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells. Cell Res. 2013 Apr;23(4):491-507.