近期论文

O’Brien MJ, Winawer SJ, Gottlieb LS, Sternberg S, Zauber A, Diaz B, Dickersin GR, Ewing S, Geller S, Kasimian D, Komorowski R, Szporn A and the National Polyp Study Workgroup. The National Polyp Study: Determinants of High Grade Dysplasia in Colorectal Adenomas. Gastroenterology, 98:371-379, 1990. PMID: 2403953
Winawer S J, Zauber A J, Ho M N, O’Brien, M J, Gottlieb L S et al. Prevention of Colorectal Cancer by Colonoscopic Polypectomy. NEJM, 329:1977-81, 1993. PMID: 8247072
O’Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, Amorosino M, Swan N.Hyperplastic (Serrated) Polyps of the Colorectum: Relationship of CpG- Island Methylator Phenotype and K-ras Mutation to Location and Histologic Subtype. Am J Surg Pathol, 2004, 28:423-434. PMID: 15087661
O’Brien MJ, Winawer SJ, Zauber AG, Bushey MT, Sternberg SS, Gottlieb LS, Bond JH, Waye JD, Schapiro M for the National Polyp Study Workgroup. Flat Adenomas in the National Polyp Study (NPS): is there an increased risk of high grade dysplasia initially or during surveillance? Clin Gastro Hepatol 2004 2(10): 905-911. PMID: 15476154
O’Brien MJ, Yang S, Mack C, Xu H, Huang CS, Mulcahy E, Amorosino M, Farraye F. Comparison of Microsatellite Instability, CpG-Island Methylation Phenotype, BRAF and KRAS Status in Serrated Polyps and Traditional Adenomas Indicates Separate Pathways to Distinct Colorectal Carcinoma Endpoints. Am J Surg Pathol 2006;30:1491-1501. PMID: 17122504
Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y, O’Brien MJ. Mutations in BRAF and KRAS Differentially Distinguish Serrated versus Non-Serrated Hyperplastic Aberrant Crypt Foci in Humans. Cancer Res. 2007,67(8):3551-4. PMID: 17440063
Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O’Brien MJ, Farraye FA. Variation in the Detection of Serrated Polyps in an Average Risk Colorectal Cancer Screening Cohort. Am J Gastroenterol. 2010 Dec;105(12):2656-64 PMID: 20717107
Zauber AG, Winawer SJ, O’Brien MJ, et al. Colonoscopic Polypectomy and Longterm Prevention of Colorectal Cancer Deaths. N Engl J Med.2012 Feb 23;366(8):687-96. PMID: 22356322
Qazi TM, O’Brien MJ, Farraye FA, Gould RW, Chen CA, Schroy PC 3rd. Epidemiology of goblet cell and microvesicular hyperplastic polyps. Am J Gastroenterol. 2014 Dec;109(12):1922-32.PMID: 25350766.
MJ O’Brien, Q Zhao, S Yang. Colorectal serrated pathway cancers and precursors. Histopathology 66 (1), 49-65, 2015. PMID: 25263173