个人简历

BSc, Chemistry and Biochemistry, Imperial College of Science and Technology, University of London, 1988.
ARCS, Imperial College of Science and Technology, University of London, 1988.
Wellcome Prize PhD in Molecular Biophysics. Thesis Title: Structural Studies of the Lipocalin Protein Family. University of Leeds, 1992.
Chartered Chemist, Royal Society of Chemistry, 1995.
Fellow of the Royal Society of Chemistry, 2005.

近期论文

Sheikh, QM, Gatherer, D, Reche, PA & Flower, DR 2016, 'Towards the knowledge-based design of universal influenza epitope ensemble vaccines' Bioinformatics, vol. Early online,10.1093/bioinformatics/btw399
Audain, E, Ramos, Y, Hermjakob, H, Flower, DR & Perez-Riverol, Y 2016, 'Accurate estimation of isoelectric point of protein and peptide based on amino acid sequences' Bioinformatics, vol. 32, no. 6, pp. 821-827,10.1093/bioinformatics/btv674
Pappalardo, F, Flower, D, Russo, G, Pennisi, M & Motta, S 2015, 'Computational modelling approaches to vaccinology' Pharmacological Research, vol. 92, pp. 40-45,10.1016/j.phrs.2014.08.006
Bunkute, E, Cummins, C, Crofts, F, Bunce, G, Nabney, IT & Flower, DR 2015, 'PIP-DB: the protein isoelectric point database' Bioinformatics, vol. 31, no. 2, pp. 295-296,10.1093/bioinformatics/btu637
Chattopadhyay, AK, Nasiev, D & Flower, DR 2015, 'A statistical physics perspective on alignment-independent protein sequence comparison.' Bioinformatics, vol. 31, no. 15, pp. 2469-2474,10.1093/bioinformatics/btv167
Molero-Abraham, M, Glutting, J-P, Flower, DR, Lafuente, EM & Reche, PA 2015, 'EPIPOX: immunoinformatic characterization of the shared T-cell epitome between variola virus and related pathogenic orthopoxviruses' Journal of Immunology Research, vol. 2015, 738020,10.1155/2015/738020
Reche, P, Flower, DR, Fridkis-Hareli, M & Hoshino, Y 2015, 'Peptide-based immunotherapeutics and vaccines 2015' Journal of Immunology Research, vol. 2015, 349049,10.1155/2015/349049
Dimitrov, I, Bangov, I, Flower, DR & Doytchinova, I 2014, 'AllerTOP v.2 - a server for in silico prediction of allergens' Journal of Molecular Modeling, vol. 20, no. 6, 2278,10.1007/s00894-014-2278-5
Reche, PA, Fernandez-Caldas, E, Flower, DR, Fridkis-Hareli, M & Hoshino, Y 2014, 'Peptide-based immunotherapeutics and vaccines' Journal of Immunology Research, vol. 2014, 256784,10.1155/2014/256784
Patronov, A, Salamanova, E, Dimitrov, I, Flower, DR & Doytchinova, I 2014, 'Histidine hydrogen bonding in MHC at pH 5 and pH 7 modeled by molecular docking and molecular dynamics simulations' Current Computer-Aided Drug design, vol. 10, no. 1, pp. 41-49,10.2174/15734099113096660050
Mumtaz, S, Flower, DR & Nabney, I 2014, 'Multi-level visualisation using Gaussian process latent variable models' . in RS Laramee, A Kerren & J Braz (eds),IVAPP 2014: proceedings of the 5th international conference on Information Visualization Theory and Applications.SciTePress, Lisbon (PT), pp. 122-129, 5th international conference on Information Visualization Theory and Applications, Lisbon, Portugal, 5-8 January.
Molero-Abraham, M, Lafuente, EM, Flower, DR & Reche, PA 2013, 'Selection of conserved epitopes from hepatitis C virus for pan-populational stimulation of T-cell responses' Clinical and Developmental Immunology, vol. 2013, 601943,10.1155/2013/601943
Flower, DR 2013, 'The immune system as drug target' Immunology and Immunogenetics Insights, vol. 5,10.4137/III.S12145
Flower, DR 2013, 'Designing immunogenic peptides' Nature Chemical Biology, vol. 9, no. 12, pp. 749-753,10.1038/nchembio.1383
Atanasova, M, Patronov, A, Dimitrov, I, Flower, DR & Doytchinova, I 2013, 'EpiDOCK: a molecular docking-based tool for MHC class II binding prediction' Protein Engineering, Design and Selection, vol. 26, no. 10, pp. 631-634,10.1093/protein/gzt018
Dimitrov, I, Flower, DR & Doytchinova, I 2013, 'AllerTOP - a server for in silico prediction of allergens' BMC Bioinformatics, vol. 14, no. Suppl.6, S4,10.1186/1471-2105-14-S6-S4
Flower, DR 2012, 'Systematic identification of small molecule adjuvants' Expert Opinion on Drug Discovery, vol. 7, no. 9, pp. 807-817,10.1517/17460441.2012.699958
Patronov, A, Dimitrov, I, Flower, DR & Doytchinova, I 2012, 'Peptide binding to HLA-DP proteins at pH 5.0 and pH 7.0: a quantitative molecular docking study' BMC Structural Biology, vol. 12, 20,10.1186/1472-6807-12-20
Flower, DR 2012, 'On the utility of alternative amino acid scripts' Bioinformation, vol. 8, no. 12, pp. 539-542,10.6026/97320630008539
Rai, J, Lok, KI, Mok, CY, Mann, H, Noor, M, Patel, P & Flower, DR 2012, 'Immunoinformatic evaluation of multiple epitope ensembles as vaccine candidates: E coli 536' Bioinformation, vol. 8, no. 6, pp. 272-275,10.6026/97320630008272