Cox,Jonathan
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B.Sc. (Hons) Medical BiochemistryPh.D. Molecular Microbiology and Drug DiscoveryLecturer in Microbiology, School of Life and Health Sciences, Aston UniversityTres Cantos Open Lab Foundation (TCOLF) Research Fellow, GSK, MadridPost-doctoral Research Associate, University of Birmingham近期论文
Abrahams KA*, Cox JAG*, Spivey VL, Loman NJ, Pallen MJ, et al. (2012) Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB. PLoS ONE 7(12): e52951. doi:10.1371/journal.pone.0052951 *These authors contributed equally to this workGurcha S, Veeraraghavan U, Cox JAG, Futterer K, Abrahams K, Bhatt A, Alderwick L, Reynolds R, Loman N, Alemparte C, Barros D, Lloyd A, Ballell L and Besra G (2014). Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS. PLoS ONE 9(11): e113568. doi:10.1371/journal.pone.0113568Mugumbate G, Abrahams KA, Cox JAG, Papadatos G, van Westen G, et al. (2015) Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation. PLoS ONE 10(3): e0121492. doi:10.1371/journal.pone.0121492Jankute M, Cox JAG, Harrison J and Besra G (2015). Assembly of the mycobacterial wall. Annual Review of Microbiology 69:405-423Cox JAG*, Abrahams K*, Alemparte C, Ghidelli-Disse S, Rullas J, Singh A, Gurcha S, Nataraj V, Remui?an M, Encinas L, Jervis P, Bhatt A, Kruse U, Bantscheff M, Fütterer K, Barros D, Ballell L, Drewes G and Besra G (2016). Target assignment of THPP inhibitors reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nature Microbiology 1(15006): doi:10.1038/nmicrobiol.2015.6Abrahams KA, Chung C, Ghidelli-Disse S, Rullas J, Rebollo-Lopez M, Gurcha SS, Cox JAG et al. (2016). A new anti-tubercular scaffold targets KasA with a novel mode of action. Nature Communications 7(12581):doi:10.1038/ncomms12581标签: 阿斯顿大学
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