个人简历

2016-date LHS Associate Dean Research
2012-date Professor of Biotechnology, Aston University
2010-2012 Director of Aston Research Centre for Healthy Ageing
2005-2012 Reader in Molecular Biosciences, Aston University
2002-2004 Innovation Fellow (40% at BPU: 60% at LHS), Aston University
2001-02 Assistant Professor, Chalmers University of Technology, G?teborg, Sweden Shareholder in the start-up company Gothia Yeast Solutions AB Co-founder and Manager of the Expression & Purification Laboratory of the SWEGENE Membrane Protein Centre
1998-01 Researcher, G?teborg University, G?teborg, Sweden (PI: Professor Stefan Hohmann)Member of EC-funded G?teborg Yeast Centre
1996-98 Fulbright Scholar, University of Michigan, USA (PI: Professor Gary Glick)
1994-96 Clinical Scientist, Department of Medical Genetics, Addenbrooke's NHS Trust, Cambridge, UK
1991-94 DPhil, Wellcome Trust Prize Student, University of Oxford (Supervisor: Professor Sabine Flitsch)
1990-91 Technical Assistant, Abel & Imray Chartered Patent Agents, UK
1986-90 BA (Hons), 1st class, Natural Science (Chemistry), University of Oxford (BA Grad. 1991 MA Grad. 1993)

近期论文

Cartwright, SP, Mikaliunaite, L & Bill, RM 2016, 'Membrane protein production in the Yeast,S. cerevisiae' . in I Mus-Veteau (ed.),Heterologous expression of membrane proteins.Methods in Molecular Biology, vol. 1432, Springer, New York (US), pp. 23-35,10.1007/978-1-4939-3637-3_2
Hardy, D, Bill, RM, Jawhari, A & Rothnie, AJ 2016, 'Overcoming bottlenecks in the membrane protein structural biology pipeline' Biochemical Society Transactions, vol. 44, no. 3, pp. 838-844,10.1042/BST20160049
Wheatley, M, Charlton, J, Jamshad, M, Routledge, SJ, Bailey, S, La-Borde, PJ, Azam, MT, Logan, RT, Bill, RM, Dafforn, TR & Poyner, DR 2016, 'GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential' Biochemical Society Transactions, vol. 44, no. 2, pp. 619-623,10.1042/BST20150284
Kitchen, P, Conner, MT, Bill, RM & Conner, AC 2016, 'Structural determinants of oligomerization of the aquaporin-4 channel' Journal of Biological Chemistry, vol. 291, no. 13, pp. 6858-6871,10.1074/jbc.M115.694729
Routledge, S, Mikaliunaite, L, Patel, A, Clare, M, Cartwright, SP, Bawa, Z, Wilks, MDB, Low, F, Hardy, D, Rothnie, AJ & Bill, RM 2016, 'The synthesis of recombinant membrane proteins in yeast for structural studies' Methods, vol. 95, pp. 26-37,10.1016/j.ymeth.2015.09.027
Kitchen, P, Day, RE, Salman, MM, Conner, MT, Bill, RM & Conner, AC 2015, 'Beyond water homeostasis: diverse functional roles of mammalian aquaporins' BBA - General Subjects, vol. 1850, no. 12, pp. 2410-2421,10.1016/j.bbagen.2015.08.023
Kitchen, P, ?berg, F, Sj?hamn, J, Hedfalk, K, Bill, RM, Conner, AC, Conner, MT & T?rnroth-Horsefield, S 2015, 'Plasma membrane abundance of human aquaporin 5 is dynamically regulated by multiple pathways' PLoS ONE, vol. 10, no. 11, e0143027,10.1371/journal.pone.0143027
Day, R, Kitchen, P, Salman, M, Bill, R, Conner, A & Conner, M 2015, 'Rapid tonicity induced re-localisation of endogenous aquaporin 4 in primary rat astrocytes - a therapeutic target for cytotoxic brain oedema?' GLIA, vol. 63, no. Suppl.S1, T13-01B, pp. E406-E407,10.1002/glia.22870
Kitchen, P, Day, RE, Taylor, LHJ, Salman, MM, Bill, RM, Conner, MT & Conner, AC 2015, 'Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel' Journal of Biological Chemistry, vol. 290, pp. 16873-16881,10.1074/jbc.M115.646034
Booe, JM, Walker, CS, Barwell, J, Kuteyi, G, Simms, J, Jamaluddin, MA, Warner, ML, Bill, RM, Harris, PW, Brimble, MA, Poyner, DR, Hay, DL & Pioszak, AA 2015, 'Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor' Molecular Cell, vol. 58, no. 6, pp. 1040-1052,10.1016/j.molcel.2015.04.018
Berger, I & Bill, RM 2015, 'Editorial overview: new protein production tools for structural biology' Current Opinion in Structural Biology, vol. 32, pp. v–vii,10.1016/j.sbi.2015.05.006
Bill, RM & von der Haar, T 2015, 'Hijacked then lost in translation: the plight of the recombinant host cell in membrane protein structural biology projects' Current Opinion in Structural Biology, vol. 32, pp. 147-155,10.1016/j.sbi.2015.04.003
Prielhofer, R, Cartwright, S, Graf, A, Valli, M, Bill, R, Mattanovich, D & Gasser, B 2015, 'Pichia pastorisregulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level' BMC Genomics, vol. 16, no. 1, 167,10.1186/s12864-015-1393-8
Jamshad, M, Charlton, J, Lin, Y-P, Routledge, SJ, Bawa, Z, Knowles, TJ, Overduin, M, Dekker, N, Dafforn, TR, Bill, RM, Poyner, DR & Wheatley, M 2015, 'G-protein-coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent' Bioscience Reports, vol. 35, no. 2, e00188,10.1042/BSR20140171
Bill, RM 2015, 'Recombinant protein subunit vaccine synthesis in microbes: a role for yeast?' Journal of Pharmacy and Pharmacology, vol. 67, no. 3, pp. 319-328,10.1111/jphp.12353
Bill, R 2015, ' Recombinant protein subunit vaccine synthesis in microbes: a role for yeast? ' Journal of pharmacy and pharmacology .
Bawa, Z, Routledge, SJ, Jamshad, M, Clare, M, Sarkar, D, Dickerson, I, Ganzlin, M, Poyner, DR & Bill, RM 2014, 'Functional recombinant protein is present in the pre-induction phases ofPichia pastoriscultures when grown in bioreactors, but not shake-flasks' Microbial Cell Factories, vol. 13, no. 1, 127,10.1186/s12934-014-0127-y
Day, RE, Kitchen, P, Owen, D, Bland, C, Marshall, L, Conner, AC, Bill, RM & Conner, MT 2014, 'Human aquaporins: regulators of transcellular water flow' BBA - General Subjects,10.1016/j.bbagen.2013.09.033
Bill, RM 2014, 'Playing catch-up withEscherichia coli: using yeast to increase success rates in recombinant protein production experiments' Frontiers in Microbiology, vol. 5, 85,10.3389/fmicb.2014.00085
Routledge, SJ, Poyner, DR & Bill, RM 2014, 'Antifoams: the overlooked additive?' Pharmaceutical Bioprocessing, vol. 2, no. 2, pp. 103-106,10.4155/pbp.14.17