个人简历

吴小梅，1969年7月，博士，硕士生导师。讲授生物化学和分子生物学理论和实验课程。主持和参加多项各级课题的研究，发表学术论文20余篇。

研究领域

主要从事脑缺血损伤的防治与神经退行性疾病分子机制的研究

近期论文

WuX,QianZM,ZhuL,DuF,YungWH,GongQ,KeY.(2011)Neuroprotectiveeffectofligustilideagainstischemia-reperfusioninjuryviaup-regulationoferythropoietinanddown-regulationofRTP801.BritishJournalofPharmacology.2011,164:332–343.

WuX,QianZ,KeY,DuF,ZhuL.(2009)GinkgolideBpreconditioningprotectsneuronsagainstischaemia-inducedapoptosis.JCellMolMed.13:4474-4483.

DuF,WuX,GongQ,HeX,KeY.(2011)Hyperthermiaconditionedastrocyte-culturedmediumprotectsneuronsfromischemicinjurybytheup-regulationofHIF-1alphaandtheincreasedanti-apoptoticability.EurJPharmacol.666:19-25.

QianZM,WuX,FanM,YangL,DuF,YungWH,KeY.(2011)Divalentmetaltransporter1isahypoxia-induciblegene.JCellPhysiol.226:1596-1603.

ZhaoW,WuX,XieH,KeY,YungWH.(2010)Permissiveroleofinsulinintheexpressionoflong-termpotentiationinthehippocampusofimmaturerats.Neurosignals.18:236-245.

ZhuL,WuX,YangL,DuF,QianZM.(2007)Up-regulationofHIF-1alphaexpressioninducedbyginkgolidesinhypoxicneurons.BrainRes.1166C:1-8.

ZhuL,KeY,WuX,LeiY,YangL,QianZM.(2008)GinkgolidesprotectPC12cellsagainsthypoxia-inducedinjurybyp42/p44MAPKpathway-dependentupregulationofHIF-1alphaexpressionandHIF-1DNA-bindingactivity.JCellBiochem.103:564-575.

DuF,QianC,QianZM,WuX,XieH,YungWH,KeY.(2011)Hepcidindirectlyinhibitstransferrinreceptor1expressioninastrocytesviaacyclicAMP-proteinkinaseapathway.Glia.59:936-945.

DuF,ZhuL,QianZM,WuX,YungWH,KeY.(2010)Hyperthermicpreconditioningprotectsastrocytesfromischemia/reperfusioninjurybyup-regulationofHIF-1alphaexpressionandbindingactivity.BiochimBiophysActa.1802:1048-1053.