个人简历

病毒学家，中国工程院院士，第三世界科学院（TWAS）院士。现任中国疾病预防控制中心首席专家，病毒病预防控制所实验室主任、研究员、博士生导师。兼任北京交通大学生命科学与生物工程研究院荣誉院长、基因工程研究所所长，北京协和医学院教授，太平洋科协公共卫生与医学委员会主席。1955年毕业于山东医学院，1960年于罗马尼亚科学院病毒学研究所获博士学位，同年归国从事医学病毒学研究。专长病毒形态学和医学超微结构学，是我国生物医学电镜技术和朊病毒研究主要开创者。首次发现人类B组轮状病毒（成人腹泻轮状病毒，ADRV）并开展系统研究，大大丰富了对轮状病毒的认识，并为20世纪80年代全国范围内的大规模成人腹泻暴发疫情的预防控制做出直接贡献；首次发现肾病综合征出血热病毒的形态，为解决该病毒久悬不决的分类学归属难题提供依据。上述成果获得世界验证和公认。与黄祯祥院士一起创建中华医学会医学病毒学分会和《中华实验和临床病毒学》杂志，先后担任四届学会主委并任杂志主编至今，为我国医学病毒学的发展、壮大和普及做出重要贡献。先后在Lancet，Journal of Virology等国内外著名专业杂志发表科学论文300余篇，著书11本，获国家自然科学奖、国家科技进步奖、何梁何利科技进步奖、WHO贡献功勋奖等奖项18项。

研究领域

生物分子光探测技术 生物化学与分子生物学 细胞生物学

近期论文

1.Yuan-Hui Fu, Yue-Ying Jiao, Jinsheng He, Gui-Yun Jiang, Wei Zahng, Yao Ma, Ying Zhang, Chang-Xin Shi, Xiang-Lei Peng, Tao Hong, Yi-Fei Yan. Sublingual administration of a helper-dependent adenoviral vector expressing the codon-optimized soluble fusion glycoprotein of human respiratory syncytial virus elicits protective immunity in mice. Antiviral Research. 2014, in press, AVR3386
2.Zhang Y, Hung T, Song J, He J. Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis. Sci China Life Sci, 2013, 56 (5) : 421-430
3.Guo L, Wang Y, Zhou H, Wu C, Song J, Li J, Paranhos-Baccalà G, Vernet G, Wang J, Hung T. Differential seroprevalence of human bocavirus species 1-4 in Beijing, China. PLoS One, 2012, 7(6): e39644
4.Liu Y, Wei H, Qu J, Wang J, Hung T. Prefibrillar aggregates of yeast prion Sup35NM and its variant are toxic to mammalian cells. Neurol Sci, 2011, 32 (6):1147-1152
5.Zhang Y, He JS, Wang X, Wang J, Bao FX, Pang SY, Yin F, Hu HG, Peng XL, Sun WM, Zheng YP, Hou LL, Hong T. Administration of A1-42 Oligomers Specific Monoclonal Antibody Improved Memory Performance in SAMP8 Mice. J Alzheimers Dis, 2011, 23 (3): 551-561
6.Zhao L, Hou X, Ji R, Han C, Yu X, Hong T. Establishment of bovine prion peptide-based monoclonal antibodies for identifying bovine prion. Sci China C Life Sci, 2009, 52(8) : 754-760
7.Liu Y, Wei H, Wang J, Qu J, Zhao W, Hung T. Effects of randomizing the Sup35NM prion domain sequence on formation of amyloid fibrils in vitro. Biochem Biophys Res Commun, 2007, 353 (1):139-146
8.Zhang Y, Qin K, Wang J, Hung T, Zhao RY. Dividing roles of prion protein in staurosporine-mediated apoptosis. Biochem Biophys Res Commun, 2006, 349 (2) : 759-768
9.Chen C(G)M, Hung T, Bridger JC, McCrae MA. Chinese adult rotavirus is a group B rotavirus. Lancet, 1985, 2 (8464):1123-1124
10.Hung T, Fan RL, Wang CA, Chen GM, Chou DN, Chang JQ, McCrae MA, Wang WZ, Se WZ, Dan R, et al. Seroepidemiology of adult rotavirus. Lancet, 1985, 2 (8450): 325-326
11.Hung T, Chen GM, Wang CG, Yao HL, Fang ZY, Chao TX, Chou ZY, Ye W, Chang XJ, Den SS, et al. Waterborne outbreak of rotavirus diarrhoea in adults in China caused by a novel rotavirus. Lancet, 1984, 1(8387): 1139-1142
12.Hung T, Chen GM, Wang CG, Chou ZY, Chao TX, Ye WW, Yao HL, Meng KH. Rotavirus-like agent in adult non-bacterial diarrhoea in China. Lancet, 1983, 2 (8358):1078-1079
13.Hung T, Xia SM, Song G, Liao HX, Chao TX, Chou ZY, Hang CS. Viruses of Classical and Mild Forms of Haemorrhagic Fiver with Renal Syndrome Isolated in China Have Similar Bunyavirus-like Morphology. Lancet, 1983, 1(8324):589-591