个人简历

2004，7－现在 在北京交通大学 生命科学与生物工程研究院工作。 2002，7 - 2004，6 在北京大学 生命科学学院做博士后。 1999，9 - 2002，7 在西北农林科技大学读博士，(其中2000, 6 – 2002, 5 在北京军事医学科学院野战输血研究所完成博士论文)。 1996，9 - 1999，7 在西北农业大学读硕士研究生。 1991，9 - 1996，7 在内蒙古农业大学读本科。 从事干细胞研究十五年，先后从事过间充质干细胞、神经干细胞、胚胎干细胞、禽类多种组织干细胞的分离分化研究；进行了间充质干细胞和胚胎干细胞用于帕金森、糖尿病、肝癌模型的生物学治疗研究。近年具体研究工作：其一是干细胞干性的长期维持与分化潜能的研究；其二是干细胞用于肿瘤等疾病模型的生物学治疗研究。

研究领域

生物化学与分子生物学 细胞生物学

近期论文

Pan M, Hou L, Zhang J, et al. Inhibitory effect and molecular mechanism of mesenchymal stem cells on NSCLC cells. Mol Cell Biochem. 2017, doi: 10.1007/s11010.-017-3174-y.(通讯作者)
Zhao D, Hou L, Pan M, et al. Inhibitory effect and mechanism of mesenchymal stem cells cultured in 3D system on hepatoma cells HepG2. Appl Biochem Biotechnol. 2017, doi:10.1007/s12010-017-2533-1(通讯作者)
Zhang J, Hou L, Zhao D, et al. Inhibitory effect and mechanism of mesenchymal stem cells on melanoma cells. Clin Transl Oncel. 2017, 19(11): 1358-1374. (通讯作者)
Cai C, Hou L, Zhang J, et al. The inhibitory effect of mesenchymal stem cell with rAd-NK4 on liver cancer. Appl Biochem Biotechnol. 2017, 183:444-459. （通讯作者）
zhang J, Hou L, Wu X, et al. Inhibitory effect of genetically engineered mesenchymal stem cells with Apoptin on hepatoma cells in vitro and in vivo. Mol Cell Biochem, 2016; 46(1-2):193-203. (通讯作者)
Hou L, Wang X, Zhou Y, et al.Inhibitory effect and mechanism of mesenchymal stem cells[J].Tumor Biololgy，Tumour Biol. 2014; 35:1239–1250.
Bai C*, Hou L*, Zhang M, et al. Identification and biological characterization of chicken embryonic cardiac progenitor cells. Cell Prolif. 2013; 46(2):232-42. （Bai C和 Hou L共同第一作者）
Bai C*, Hou L*, Ma Y, et al. Isolation and characterization of mesenchymal stem cells from chicken bone marrow. Cell Tissue Bank. 2013;14(3):437-51 Doi: 10.1007/s10561-012-9347-8 （Bai C和 Hou L共同第一作者）
Bai C*, Hou L*, Zhang M, et al. Characterization of vascular endothelial progenitor cells from chicken bone marrow. BMC Vet Res. 2012; 8:54-64. （Bai C和 Hou L共同第一作者）
Bai C, Hou L, Li F, et al. Isolation and biological characteristics of beijing Fatty chicken skeletal muscle satellite cells. Cell Commun Adhes. 2012; 19(5-6):69-77. doi: 10.3109/15419061.2012.743998.
Hou L, Jin D, Gu E, et al. Isolation and Characterization of Duck Embryonic Neural Stem/Progenitor Cells. Poultry Science，2011，90(3):609-17.
Gong X*, Hou L*, Bai C, et al. Isolation and Biological Characteristics of Chicken Adipose-Derived Progenitor Cells. DNA and cell biology. 2011, 30(7): 453-460. doi:10.1089/dna.2010.1154.（Gong X和 Hou L共同第一作者）
Hou L, Liu Y, Wang X, et al. The effects of amyloid-β42 oligomer on the proliferation and activation of astrocytes in vitro. In vitro Cell Dev-Animal. 2011, 47(8):573-80. doi: 10.1007/s11626-011-9439-y
Wang Y*, Hou L*, Li C, et al. Isolation, Culture and Biological charateristics of Primordial germ cells from Beijing fatty chicken. Journal of Reproduction and Development. 2010，56（3):303-308 （Wang Y和Hou L为共同第一作者）
Guan W*, Wang Y*, Hou L, er al. Derivation and Characteristics of Pluripotent Embryonic germ cells in Duck. Poultry Science. 2010, 89(2):312-7
Hou L, Du J, Wang J, et al. Expression of IL-13Rα2 in liver cancer cells and its effect on targeted therapy of liver cancer. Journal of Cancer Research and Clinical Oncology. 2010, 136(6):839-846.
Hou LL, Hong T. Stem cells and neurodegenerative diseases. Sci China Ser C-Life Sci. 2008, 51(4): 287-294.
Shi Y*, Hou L*, Tang F*, et al. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells. 2005, 23:93-102.（Shi Y 和Hou L,Tang F为共同第一作者）
Wang X, Hu J, Zhao D, Wang G, Tan L, Du L, Yang J, Hou L, Zhang H, Yu Y, Zhang H, Deng H, Ding M. Nestin-CD24low/-population from fetal Nestin-EGFP transgenic mice enriches the pancreatic endocrine progenitor cells. Pancreas. 2005, 31(4):385-391. ）
Hou L, Cao H, Wang D, et al. Induce umbilical cord blood mesenchymal stem cell into neuron-like cells in vitro. International Journal of Hematology. 2003, 78(3): 256-261
Wang X, Peng H, Hou L, et al. Synthesis of ratiometric fluorescent nanoparticles for sensing oxygen[J]。MICROCHIMICA ACTA，2012-05，178（1-2），145：172