个人简历

主要教育、科研简历\r
1991-1996 天津医科大学医疗系，临床医学 医学学士学位\r
1996-2001 中国协和医科大学，皮肤与性病学 医学博士学位\r
2001-2004 北京航空航天大学，生物工程系 讲师\r
2004-2008 北京航空航天大学，生物工程系 副教授、副主任\r
2005-2006 德国柏林自由大学&洪堡大学Charité医学院 访问学者 \r
2008-2010 北京航空航天大学，生物与医学工程学院 副教授、副院长\r
2010 Charité医科大学，柏林空天医学中心 访问学者\r
2010-2012 北京航空航天大学，生物与医学工程学院 教授、副院长\r
2015 德州大学圣安东尼奥分校 访问学者\r
2016 Charité医科大学，柏林空天医学中心 高级访问学者\r
2017 英国伦敦大学学院 高级访问学者\r
2012-现在 北京航空航天大学，生物与医学工程学院 教授、工会主席\r
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主要社会兼职\r
中国空间科学学会空间生命专业委员会副主任委员\r
中国空间科学学会常务理事\r
全国空间科学及应用标准化技术委员会（生命交叉科学）标准化工作组成员

研究领域

航空航天生物医学工程\r
空间生命科学\r
生物力学与力生物学""

近期论文

Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Lianwen Sun*, Yubo Fan*. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes. Biochemical and Biophysical Research Communications, 2020, 530: 167-172.\r
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Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Cai He, Lianwen Sun*, Yubo Fan*. Pharmacological Regulation of Primary Cilium Formation Affects the Mechanosensitivity of Osteocytes. Calcified Tissue International, 2020: 1-11.\r
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Wen Xiao, Qixiang Wang, Feng Pan, Runyu Cao, Xintong Wu, Lianwen Sun*. Adaptive frequency filtering based on convolutional neural networks in off-axis digital holographic microscopy. Biomedical Optical Express. 2019, 10.\r
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Xintong Wu, Wen Xiao, Runyu Cao, Xiao Yang, Feng Pan, Lianwen Sun*, Yubo Fan*. Spontaneous cellular vibratory motions of osteocytes are regulated by ATP and spectrin network. Bone, 128 (2019), 112056.\r
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Shouhui Wang, Wenting Li, Xiao Yang, Yunfei Huang, Lianwen Sun*, Yubo Fan. Musculoskeletal alterations of hindlimb during simulated microgravity and reloading in rats: compared by gender. Microgravity Science and Technology. 2019, 31(4): 347-355. \r
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Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Lianwen Sun*, Yubo Fan*. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes. Biochemical and Biophysical Research Communications, 2020, 530: 167-172.\r
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Shouhui Wang, Xiao Yang, Min Wang, Yunfei Huang, Dieter Blottner, Lianwen Sun*, Yubo Fan*. The role of body fluid shifts on hindlimb bone loss in tail suspended rats using a novel body fluid alteration device. Acta Astronautica. 2019, 159:1-7.\r
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Yunfei Huang, Huiqin Luan, Lianwen Sun*, Shouhui Wang, Yubo Fan*. Increased Blood Flow by Unilateral Intermittent Compression on Hindlimbs May Prevent Bone Loss. Microgravity Science and Technology, 2018, 30: 987-993.\r
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Lianwen Sun, Shuang Li, Xiao Yang, Fang Pu, Hongyu Qi*, Yubo Fan*. Contribution of bone micromechanical behavior beyond lamellar length scale to the macroscopic bone quality of hind limb unloading rats. Acta Astronautica. 2018, 152: 468–473.\r
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Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun*, Dieter Blottner. Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse. Frontiers in Physiology, 2018, 9: 616.\r
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Xiao Yang, Lianwen Sun*, Chengfei Du, Xintong Wu, Yubo Fan*. Finite element analysis of osteocytes mechanosensitivity under simulated microgravity, Microgravity Science and Technology, 2018, 30: 469-481.\r
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Runyu Cao, Wen Xiao, Xintong Wu, Lianwen Sun*, Feng Pan*. Quantitative observations on cytoskeleton changes of osteocytes at different cell parts using digital holographic microscopy. Biomedical Optics Express 2018, 9(1): 72-85.\r
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Yunfei Huang, Huiqin Luan, Lianwen Sun*, Jingfang Bi, Ying Wang, Yubo Fan*. Local vibration enhanced the efficacy of passive exercise on mitigating bone loss in hindlimb unloading rats. Acta Astronautica, 2017, 137: 373-381.\r
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Xintong Wu, Lianwen Sun*, Xiao Yang, Dong Ding, Dong Han, Yubo Fan*. The potential role of spectrin network in the mechanotransduction of MLO-Y4 osteocytes. Sci Rep. 2017, 7: 40940.\r
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Wenting Li, Yunfei Huang, Lianwen Sun*, Huiqin Luan, Baozhang Zhu, Yubo Fan*. Would interstitial fluid flow be responsible for skeletal maintenance in tail-suspended rats? [J]. Microgravity Science and Technology, 2017(29): 107-114.\r
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Xiao Yang, Ahmed JenanMostafa, Mark Appleford, Lianwen Sun*, Xiaodu Wang*. Bone formation is affected by matrix advanced glycation end products (AGEs) in vivo. Calcified tissue international 2016, 99(4): 373-383.\r
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Xintong Wu, Lianwen Sun*, Hongyu Qi, Hao Shi, Yubo Fan*. The bio-response of osteocytes and its regulation on osteoblasts under vibration. Cell Biology International, 2016, 40(4): 397-406.\r
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Huiqin Luan, Lianwen Sun*, Yunfei Huang, Xintong Wu, Haijun Niu, Hong Liu, Yubo Fan*. Use of micro-computed tomography to evaluate the effects of exercise on preventing the degeneration of articular cartilage In tail-suspended rats. Life Sciences in Space Research, 2015, 6, 15-20.\r
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Xiao Yang, Chintan Gandhi, Md. MizanurRahman, Mark Appleford, Lianwen Sun*,Xiaodu Wang*. Age-related effects of advanced glycation end products (ages) in bone matrix on osteoclastic resorption. Calcified tissue international, 2015, 97:592-601.\r
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Xiao Yang, Lianwen Sun*, Xintong Wu, Meng Liang, Yubo Fan*. Impact of shear stress and simulated microgravity on osteocytes using a new rotation cell culture device.ActaAstronautica, 2015, 116, 286-298.\r
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Xiao Yang, Lianwen Sun*, Meng Liang, Xiaonan Wang, Yubo Fan*. The response of wnt/β-catenin signaling pathway in osteocytes under simulated microgravity. Microgravity Science and Technology. 2015, 27:473-483.\r
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Lianwen Sun*, Yunfei Huang, Ying Wang , Hui-Qin Luan, Yubo Fan*,Comparison of bone histomorphometry and μCT for evaluating bone quality in tail-suspended rats. Life Sciences in Space Research, 2014, 3,18-23.\r
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Huiqin Luan, Lianwen Sun*, Yunfei Huang, Ying Wang, Colin J. McClean, Yubo Fan*. The application of micro-CT in monitoring bone alterations in tail-suspended rats in vivo. Advances in Space Research, 2014, 53(11): 1567-1573.\r
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Lianwen Sun*, Huiqin Luan, Yunfei Huang, Ying Wang, Yubo Fan. Effects of local vibration on bone loss in tail-suspended rats. Int J Sports Med, 2014,35(7): 615-624.\r
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Lianwen Sun, Blottner Dieter, Huiqing Luan, Salanova Michele, Wang Chao, Haijun Niu, Felsenberg Dieter, Yubo Fan. Bone and muscle structure and quality preserved by active versus passive muscle exercise on a new stepper device in 21 days tail-suspended rats.J Musculoskelet Neuronal Interact. 2013, 13(2):166-77.\r
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Xiao Yang, Lianwen Sun*, Xintong Wu, Xiaonan Wang, Yubo Fan. Effect of simulated microgravity on osteocytes responding to fluid shear stress[J]. Acta Astronautica, 2013, 84(MAR.-APR.):237-243.\r
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Lianwen Sun, Chao Wang, Fang Pu, Deyu Li, Haijun Niu, Yubo Fan*. Comparative Study on Measured Variables and Sensitivity to Bone Microstructural Changes Induced by Weightlessness Between In Vivo and Ex Vivo Micro-CT Scan. Calcified Tissue International(Calcified Tissue Int),2011, 88(1):48-53.\r
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Beller Gisela, Belavy Daniel, Lianwen Sun, Armbrecht Gabi, Alexandre Christian, Felsenberg Dieter. WISE-2005: bed-rest induced changes in bone mineral density in women during 60 days simulated microgravity. Bone, 2011, 49(4):858-66.\r
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Xiao Yang, Lianwen Sun, Xiaonan Wang, Yubo Fan*. Effects of simulated microgravity on the mechanosensibility of osteocytes due to fluid shear stress. Bone, 2010, Vol 47(S3), S436-S437.\r
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Lianwen Sun, Chao Wang, Tian Xie, Fang Pu, Yao Sun, Yubo Fan*. Body-weight distribution on forelimbs in rat tail-suspension model[J]. Aviakosmicheskaya i Ekologicheskaia Meditsina（Aerospace and environmental medicine）, 2010, 44(1):37-39.