个人简历

教育背景： 2008. 01-2012. 12：Stevens Institute of Technology化学生物学专业 博士 2004. 09-2007. 07：清华大学 生物科学专业 硕士 2000. 09-2004. 07：清华大学 生物科学专业 学士 工作经历： 2013. 09-至今：北京化工大学 生命科学与技术学院 副教授 其中2014.09-2016.03：塔里木大学 生命科学学院 副院长（援疆干部）

研究领域

1）多肽药物及天然产物中的生物活性多肽 2）药物递送 3）多肽材料

近期论文

1) Ruru Fan, Yanyan Yuan, Qiang Zhang, Xi Rui Zhou, Lili Jia, Zhuqing Liu, Changyuan Yu, Shi Zhong Luo, Long Chen*. Isoleucine/leucine residues at “a” and “d” positions of a heptad repeat sequence are crucial for the cytolytic activity of a short anticancer lytic peptide. Amino Acids. 2017, 49(1): 193-202.
2) Long Chen, Qiang Zhang, Xiushuang Yuan, Yimeng Cao, Yanyan Yuan, Huiwei Yin, Xiufang Ding, Zhentai Zhu, Shi-Zhong Luo. How Charge Distribution Influences the Function of Membrane-active Peptides: Lytic or Cell-Penetrating? International Journal of Biochemistry & Cell Biology, 2017, 83: 71-75.
3) X.R. Zhou, Q. Zhang, X.B. Tian, Y.M. Cao, Z.Q. Liu, R. Fan, X.F. Ding, Z. Zhu, L. Chen* and S.Z. Luo*. From a pro-apoptotic peptide to a lytic peptide: One single residue mutation. Biochim. Biophys. Acta.-Biomembranes. 2016, 1858 (8): 1914-1925.
4) X. Tian, F. Sun, X.R. Zhou, S.Z. Luo and L. Chen. Role of peptide self-assembly in antimicrobial peptides. Journal of Peptide Science. 2015, 21(7): 530-539.
5) L. Chen and J. F. Liang. The Potential Roles of Cell Surface pHs in Bioactive Peptide Activation. Chemical Biology and Drug Design. 2015, 85(2): 208-215.
6) Y. Sun#, L. Chen#, F. Sun, X. Tian and S. Luo. New Amphiphilic N-phosphoryl Oligopeptides Designed for Gene Delivery. International Journal of Pharmaceutics, 2014, 468 (1-2):83-90.
7) L. Chen and J. F. Liang. Peptide fibrils with altered stability, activity, and cell selectivity. Biomacromolecules, 2013, 14(7): 2326-2331.
8) L. Chen, N. Patrone, J.F. Liang. Peptide self-assembly on cell membranes to induce cell lysis. Biomacromolecules, 2012, 13(10): 3327-3333.
9) L. Chen, Z. Tu, N. Voloshchuk, and J. F. Liang. Lytic Peptides with Improved Stability and Selectivity Designed for Cancer Treatment. Journal of Pharmaceutical Sciences. 2012, 101: 1508-1517.
10) L. Chen and J. F. Liang. Metabolic Oligosaccharides Altered Cell Responses to Anticancer Drugs. European Journal of Pharmaceutics and Biopharmaceutics. 2012, 81: 339-345.