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陈必强
2023-05-06 09:44
  • 陈必强
  • 陈必强 - 教授-北京化工大学-生命科学与技术学院-个人资料

近期热点

资料介绍

个人简历


教育背景: 2001 学士,生物化工(北京化工大学) 2003 硕士,生物化工(北京化工大学) 2008 博士,生物化工(北京化工大学) 2006/01-2006/07 赴丹麦技术大学进行博士联合培养 2008.8-2010.6 博士后(清华大学化工系) 工作经历: 2010.8-2014.12,北京化工大学生命学院,副教授,硕士生导师 2015.1-2018.1,北京化工大学生命学院,见习教授,硕士生导师 2018.1-至今,北京化工大学生命学院,教授,博士生导师

研究领域


长期从事生物催化剂工程的研究。作为项目负责人主持国家自然科学基金2项、国家973计划子课题2项、863计划子课题1项,企业横向课题2项。近年发表SCI论文30多篇,申请专利11项(已授权6项,包括国际专利1项)。具体研究方向: 新酶的筛选与酶的蛋白质工程改造 酶的固定化微环境调控 多酶催化体系构建 新型酶反应器设计与酶反应过程在线监测、控制与系统集成 生物催化新产品、新工艺开发

近期论文


1)Cui C, Chen H, Chen B*, et al. Genipin Cross-Linked Glucose Oxidase and Catalase Multi-enzyme for Gluconic Acid Synthesis (2016). Applied Biochemistry and Biotechnology, 1-10.
2)Cui, C., Nan, G., Chen, X., Chen, B*., & Tan, T*. (2016). Immobilization of yarrowia lipolytica, lipase ylip 2 for the bioicatalytic synthesis of phytosterol ester in a water activity controlled reactor. Colloids & Surfaces B Biointerfaces, 146, 490-497.
3)Cui, C., Zhen, Y., Qu, J., Chen, B*., & Tan, T*. (2016). Synthesis of biosafe isosorbide dicaprylate ester plasticizer by lipase in a solvent-free system and its sub-chronic toxicity in mice. Rsc Advances, 6(15), 11959-11966.
4)Tao, Y., Dong, R., Pavlidis, I. V., Chen, B*., & Tan, T. (2015). Using imidazolium-based ionic liquids as dual solvent-catalysts for sustainable synthesis of vitamin esters: inspiration from bio- and organo-catalysis. Green Chemistry, 18(5), 1240-1248.
5)Tao, Y., Chen, G., Pavlidis, I. V., Jiang, Y., Qie, L., & Cui, C., Liu L., Chen, B*, & Tan, T.* (2015). Water-dependent kinetics guide complex lipase-mediated synthesis of biolubricants in a water activity control reactor. Catalysis Science & Technology, 5(12), 5120-5128.
6)Cui, C., Tao, Y., Ge, C., Zhen, Y., Chen, B*., & Tan, T*. (2015). Synergistic effects of amine and protein modified epoxy-support on immobilized lipase activity. Colloids & Surfaces B Biointerfaces, 133(1), 51-57.
7)Rong, X., Cui, C., Chen, B*., & Tan, T. (2015). Immobilizing yarrowia lipolytica, lipase lip2 via improvement of microspheres by gelatin modification. Applied Biochemistry & Biotechnology, 177(3), 1-9.
8)Cui, C., Xie, R., Tao, Y., Zeng, Q., Chen, B*, & Tan T*. (2015). Improving performance of yarrowia lipolytica, lipase lip2-catalyzed kinetic resolution of (R,S)-1-phenylethanol by solvent engineering. Biocatalysis & Biotransformation, 33(1), 38-43.
9)Tao, Y., Cui, C., Shen, H., Luo, L., Chen, B*., & Tan, T*. (2014). Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. Enzyme & Microbial Technology, 58-59(9), 60-67.
10)Chen, Biqiang,Zhang, Hong,Cheong, Ling-Zhi,Tan, Tianwei,Xu, Xuebing ,Enzymatic Production of ABA-Type Structured Lipids Containing Omega-3 and Medium-Chain Fatty Acids: Effects of Different Acyl Donors on the Acyl Migration Rate,Food and Bioprocess Technology,2012,5(2):541-547

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