刘蕾
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个人简历
个人简历1998.09-2002.07中国农业大学生物学院生物科学专业学士2002.09-2007.07中国农业大学生物学院生理学博士2007.07-2011.12中国科学院动物研究所助理研究员2012.01-2015.07中国科学院动物研究所副研究员2015.08至今北京工商大学理学院副研究员学术成就主要从事细胞生物学及发育生物学研究,利用细胞模型开展细胞干性、发育潜能研究及应用安全性评估,并对其调控自我更新和分化的分子机制进行探索。工作期间共发表SCI论文17篇,以第一或共同第一作者发表论文3篇(第一作者影响因子共计21.776),先后主持4项国家级项目,申请发明专利1项。撰写专著1.《再生医学——理论与技术》,科学出版社,2010年,北京2.《新生物学年鉴2013》,科学出版社,2013年,北京3.《生物学实验指南丛书——干细胞实验指南》,中央广播电视大学出版社,2015年,北京近期论文
1.LiZ,WangL,WangY,LiuL,WangL,LiW,ZhouQ.GenerationofanLncRNAGtl2-GFPReporterforRapidAssessmentofPluripotencyinMouseInducedPluripotentStemCells.JGenetGenomics.20;42(3)(2015):125-8.IF=2.9242.GuoCL#,LiuL#,JiaYD,ZhaoXY,ZhouQ,WangL*.AnovelvariantofOct3/4geneinmouseembryonicstemcells.StemCellResearch9(2)(2012):69-76.(共同第一作者)IF=4.4673.LiW#,ShuaiL#,WanHF#,DongMZ#,WangM,SangLS,FengCJ,LuoGZ,LiTD,LiX,WangLB,ZhengQY,ShengC,WuHJ,LiuZH,LiuL,WangL,WangXJ,ZhaoXY*,ZhouQ*.Androgenetichaploidembryonicstemcellsproducelivetransgenicmice.Nature490(7420)(2012):407-411.IF=42.3514.ShengC#,ZhengQY#,WuJY#,XuZ,SangLS,WangLB,GuoCL,ZhuWW,TongM,LiuL,LiW,LiuZH,ZhaoXY,WangL,ChenZG*,ZhouQ*.Generationofdopaminergicneuronsdirectlyfrommousefibroblastsandfibroblast-derivedneuralprogenitors.CellResearch22(4)(2012):769-772.IF=11.9815.ShengC#,ZhengQY#,WuJY#,XuZ,WangLB,LiW,ZhangHJ,ZhaoXY,LiuL,WangZW,GuoCL,WuHJ,LiuZH,WangL,HeSG,WangXJ,ChenZG*,ZhouQ*.Directreprogrammingofsertolicellsintomultipotentneuralstemcellsbydefinedfactors.CellResearch22(1)(2012):208-218.IF=11.9816.LiTD#,ZhaoXY#,TengF,LiX,JiangMG,LiW,WangXP,WangJL,LiuL,LiuZH,WangL,ZhouQ*.DerivationofGermlineCompetentRatEmbryonicStemCellsfromDARats.JournalofGeneticsandGenomics39(11)(2012):603-606.IF=2.9247.GuQ#,HaoJ#,ZhaoXY,LiW,LiuL,WangL,LiuZH,ZhouQ*.RapidconversionofhumanESCsintomouseESC-likepluripotentstatebyoptimizingcultureconditions.Protein&Cell3(1)(2012):71-79.IF=3.228.TongM#,LvZ#,LiuL#,ZhuH#,ZhengQY#,ZhaoXY,LiW,WuYB,ZhangHJ,WuHJ,LiZK,ZengFY,WangL,WangXJ,ShaJH*,ZhouQ*.MicegeneratedfromtetraploidcomplementationcompetentiPScellsshowsimilardevelopmentalfeaturesasthosefromEScellsbutarepronetotumorigenesis.CellResearch21(11)(2011):1634-1637.(共同第一作者)IF=11.9819.LiW#,ZhaoXY#,WanHF,ZhangY,LiuL,LvZ,WangXJ,WangL*,ZhouQ*.iPScellsgeneratedwithoutc-MychaveactiveDlk1-Dio3regionandarecapableofproducingfull-termmicethroughtetraploidcomplementation.CellResearch21(3)(2011):550-553.IF=11.98110.RiazA#,ZhaoXY#,DaiXP#,LiW,LiuL,WanHF,YuY,WangL,ZhouQ*.Mousecloningandsomaticcellreprogrammingusingelectrofusedblastomeres.CellResearch21(5)(2011):770-778.IF=11.98111.LiuL#,LuoGZ#,YangW#,ZhaoXY#,ZhengQY,LvZ,LiW,WuHJ,WangL,WangXJ*,ZhouQ*.ActivationoftheimprintedDlk1-Dio3regioncorrelateswithpluripotencylevelsofmousestemcells.JournalofBiologicalChemistry285(25)(2010):19483-19490.IF=5.32812.ZhouSY#,DingCH#,ZhaoXY#,WangEY,DaiXP,LiuL,LiW,LiuZC,WanHF,FengCJ,HaiH,WangL,ZhouQ*.Successfulgenerationofclonedmiceusingnucleartransferfrominducedpluripotentstemcells.CellResearch20(7)(2010):850-853.IF=11.98113.ZhaoXY#,LiW#,LvZ#,LiuL,TongM,HaiT,HaoJ,WangX,WangL,ZengFY*,ZhouQ*.ViablefertilemicegeneratedfromfullypluripotentiPScellsderivedfromadultsomaticcells.StemCellReviewsandReports6(3)(2010):390-397.IF=6.77414.ZhaoXY#,LiW#,LvZ#,LiuL,TongM,HaiT,HaoJ,GuoCL,WangX,WangL,ZengFY*,ZhouQ*.Efficientandrapidgenerationofinducedpluripotentstemcellsusingalternativeculturemedium.CellResearch20(3)(2010):383-386.IF=11.98115.ZhaoXY,LvZ,LiuL,WangL,TongM,ZhouQ*.DerivationofembryonicstemcellsfromBrownNorwayratsblastocysts.JournalofGeneticsandGenomics37(7)(2010):467-473.IF=2.92416.ZhaoXY#,LiW#,LvZ#,LiuL,TongM,HaiT,HaoJ,GuoCL,MaQW,WangL,ZengFY*,ZhouQ*.iPScellsproduceviablemicethroughtetraploidcomplementation.Nature461(7260)(2009):86-90.IF=42.351 相关热点