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金建明
2023-05-06 09:15
  • 金建明
  • 金建明 - 博士 教授 硕士生导师-北京工商大学-理学院-个人资料

近期热点

资料介绍

个人简历


个人简历:
1993年毕业于武汉大学生命科学学院生物化学专业,获理学学士学位;
1997年毕业于武汉大学生命科学学院生物化学专业,获理学硕士学位;
2002年毕业于中国科学院昆明植物研究所植物化学专业,获理学博士学位;
1993年至1994年在浙江永宁药业股份有限公司工作;
1997年至1999年中国科学院水生生物研究所工作;
2002年至2009年在韩国首尔大学农学与生命科学学院从事研究工作;
2009年至2010年在香港浸会大学生物学从事研究工作;
2010年至2011年在美国奥克拉荷马大学从事研究研究;
2011年至2012年在云南民族大学化学与生物技术学院工作;
2012年至今在北京工商大学理学院工作。
主要学术成就:
现主持二项国家自然科学基金和一项北京市自然科学基金。

研究领域


1.化妆品植物原料的提取分离工艺和功能性活性成分研究
2.植物原料的生物转化技术研究
3.基因工程高效合成活性成分及其功效评价研究
4.芦荟产品的质量安全研究"主要研究领域:
植物原料活性成分及其功效评价,活性成分的生物合成及其功效评价"

近期论文


1.WeiChen,JunYao,JieMeng,WenjingHan,YongTao,YihuaChen,YixinGuo,GuizhiShi,YangHe,Jian-MingJin*andShuang-YanTang*.Promiscuousenzymaticactivity-aidedmultiple-pathwaynetworkdesignformetabolicfluxrearrangementinhydroxytyrosolbiosynthesis.NatureCommunications,2019,10:960.
2.ChenWei,ZhangXuanxuan,XiongDandan,JinJian-Ming*andTangShuang-Yan*.Engineeringtheeffectorspecificityofregulatoryproteinsfortheinvitrodetectionofbiomarkersandpesticideresidues.AppliedMicrobiologyandBiotechnology,2019,103(7):3205–3213.
3.HengLi,JingLi,RuinanJin,WeiChen,ChaoningLiang,JieyuanWu,Jian-MingJin,Shuang-YanTang*.Towardstheconstructionofhigh-qualitymutagenesislibraries.BiotechnologyLetter,2018,40:1101–1107.
4.HengLi,WeiChen,Rui-NanJin,Jian-MingJin*,Shuang-YanTang*.Biosensor‑aidedhigh‑throughputscreeningofhyper‑producingcellsformalonyl‑CoA‑derivedproducts.MicrobialCellFactories,2017,16:187.
5.HengLi,ChaoningLiang,WeiChen,Jian-MingJin*,Shuang-YanTang*,YongTao.Monitoringinvivometabolicfluxwithadesignedwhole-cellmetabolitebiosensorofshikimicacid.BiosensorsandBioelectronics,2017,98:457–465.
6.JieyuanWu,PeixiaJiang,WeiChen,DandanXiong,LinglanHuang,JunyingJia,YuanyuanChen,Jian-MingJin*,Shuang-YanTang*.Designandapplicationofalactulosebiosensor.ScientificReports,2017,7:45994.
7.DandanXiong,ShikunLua,JieyuanWu,ChaoningLiang,WeiWang,WenzhaoWang,Jian-MingJin*,Shuang-YanTang*.Improvingkeyenzymeactivityinphenylpropanoidpathwaywithadesignedbiosensor.MetabolicEngineering,2017,40:115-123.
8.You-HaiLi,Wen-JinHan,Xi-WuGui,TaoWei,Shuang-YanTang,Jian-MingJin*.PutativenonribosomalpeptidesynthetaseandcytochromeP450genesresponsiblefortentoxinbiosynthesisinAlternariaalternataZJ33.Toxins,2016,8:234.
9.ChaoningLiang,YiZhang,YanJia,WenzhaoWang,YouhaiLi,ShikunLu,Jian-MingJin*,Shuang-YanTang*.Engineeringacarbohydrate-processingtransglycosidaseintoglycosyltransferasefornaturalproductglycodiversification.ScientificReports,2016,6:21051.
10.LinZhu,ZheWu,Jian-MingJin,Shuang-YanTang*.Directedevolutionofleucinedehydrogenaseforimprovedefficiencyofl-tert-leucinesynthesis.AppliedMicrobiologyandBiotechnology,2016,100:5805–5813.
11.PeixiaJiang,ShanshanMu,HengLi,YouhaiLi,CongminFeng,Jian-MingJin*andShuang-YanTang*.Designandapplicationofanovelhigh-throughputscreeningtechniquefor1-deoxynojirimycin.ScientificReports,2015,5:8563.
12.HokyoungSon,Young-SuSeo,KyunghunMin,AeRanPark,JungkwanLee,Jian-MingJin,YangLin,PeijianCao,Sae-YeonHong,Eun-KyungKim,Seung-HoLee,AramCho,SeunghoonLee,MyungguKim,YongsooKim,Jung-EunKim,Jin-CheolKim,GyungJaChoi,Sung-HwanYun,JaeYunLim,MinkyunKim,Yong-HwanLee,Yang-DoChoi,Yin-WonLee*.Aphenome-basedfunctionalanalysisoftranscriptionfactorsinthecerealheadblightFungus,Fusariumgraminearum.PLoSPathogens,2011,7:e1002310.
13.Jian-MingJin,SeunghoonLee,JungkwanLee,Seung-RyulBaek,Jin-CheolKim,Sung-HwanYun,Sook-ToungPark,SeogchanKangandYin-WonLee*.FunctionalcharacterizationandmanipulationoftheapicidinbiosyntheticpathwayinFusariumsemitectum.MolecularMicrobiology.2010,76:456-466.
14.Jian-MingJin,Jung-KuanLeeandYin-WonLee*.CharacterizationofthecarotenoidbiosyntheticgenesintheascomyceteGibberellazeae.FEMSMicrobiologyLetters.2010,320:197-202.
15.Ju-YoungPark,JianmingJin,Yin-WonLee,SeogchanKang,andYong-HwanLee*.RiceblastfungusMagnaportheoryzaeinfectsArabidopsisthalianaviaadistinctmechanismfromthatrequiredfortheinfectionofrice.PlantPhysiology,2009,149:474-486.
16.JianmingJin,Seung-RyulBaek,Kyung-RimLee,Jung-kwanLee,Sung-HwanYun,SeogchanKangandYin-WonLee*.PurificationandphytotoxicityofapicidinsproducedbytheFusariumsemitectumKCTC16676.ThePlantPathologyJournal,2008,24:385-388.
17.Jung-EunKim,Jin-CheolKim,JianmingJin,Sung-HwanYunandYin-WonLee*.FunctionalcharacterizationofgeneslocatedattheaurofusarinbiosynthesisgeneclusterinGibberellazeae.ThePlantPathologyJournal,2008,24:8-16.
18.Jung-EunKim,JianmingJin,HunKim,Jin-CheolKim,Sung-HwanYun,andYin-WonLee*.GIP2,aPutativeTranscriptionFactorThatRegulatestheAurofusarinBiosyntheticGeneClusterinGibberellazeae.AppliedandEnvironmentalMicrobiology,2006,72:1645-1652.
19.Yong-TaeKim,Ye-RyunLee,JianmingJin,Kap-HoonHan,HunKim,Jin-CheolKim,TheresaLee,Sung-HwanYun,andYin-WonLee*.TwodifferentpolyketidesynthasegenesarerequiredforsynthesisofzearalenoneinGibberellazeae.MolecularMicrobiology,2005,58:1102–1113.
20.Jung-EunKim,Kap-HoonHan,JianmingJin,HunKim,Jin-CheolKim,Sung-HwanYunandYin-wonLee*.PutativepolyketidesynthaseandlaccasegenesforbiosynthesisofaurofusarininGibberellazeae.AppliedandEnvironmentalMicrobiology,2005,71:1701-1708.
21.Yung-JinChang,Jian-MingJin,Hee-YoungNamandSoo-UnKim*.Pointmutationof(+)-germacreneAsynthasefromIxerisdentate.BiotechnologyLetters,2005,27:285-288.
22.Min-YoungKim,Yung-JinChang,Myun-HoBang,Nam-InBaek,Jian-MingJin,Cheol-HoLeeandSoo-UnKim*.cDNAisolationandcharacterizationof(+)-germacreneAsynthasefromIxerisdentateform.AlbifloraHara.JournalofPlantBiology,2005,48:178-186.
23.Jian-MingJin,Yin-JunZhang,Hai-zhouLiandChong-renYang*.CytotoxicsteroidalsaponinsfromPolygonatumzanlanscianense.JournalofNaturalProducts,2004,67:1992-1995.
24.Jian-MingJin,Ying-JunZhang,andChong-RenYang*.FournewsteroidconstituentsfromthewasteresidueoffibreseparationfromAgaveamericanaleaves.Chemical&PharmaceuticalBulletin,2004,52:654-658.
25.Jian-MingJin,Ying-JunZhang,andChong-RenYang*.SpirostanolandfurostanolglycosidesfromthefreshtubersofPolianthestuberosa.JournalofNaturalProducts,2004,67:5-9.
26.Jian-MingJin,Xi-KuiLiu,andChong-RenYang*.ThreenewhecogeninglycosidesfromfermentedleavesofAgaveamericana.JournalofAsiannaturalproductsResearch,2003,5:95-103.
27.JianmingJin,andChongrenYang*.TwonewsteroidalsapogeninsfromfermentedleavesofAgaveamericana.ChineseChemicalLetters,2003,14:491-494.
28.JianmingJin,XikuiLiu,andChongrenYang*.AnewcholestaneglycosidefromthetubersofPolianthestuberosa.ActaBotanicaYunnanica,2003,25:107-110.
29.JINJian-Ming,LIUXi-kui,TENGRong-WeiandYANGChong-Ren*.Enzymaticdegradationofparvifloside.ActaBotanicaSinica,2002,44:1243-1249.
30.JianmingJin,XikuiLiu,RongweiTengandChongrenYang*.TwonewsteroidalglycosidesfromfermentedleavesofAgaveamericana.ChineseChemicalLetters,2002,13:629-632.
31.JianmingJin,XikuiLiu,andChongrenYang*.AnewsteroidalsaponinfromfermentedleavesofAgaveamericana.ActaBotanicaYunnanica,2002,24:539-542.
32.JianmingJin,XikuiLiu,andChongrenYang*.AnewpregnaneglycosidefromfermentedleavesofAgaveamericana.ChineseChemicalLetters,2002,13:1189-1192.

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