个人简历

1971年5月出生于黑龙江省甘南县查哈阳农场 1988.9- 1992.7 黑龙江中医药大学中药系学习，获学士学位 1992.9- 1995.7 黑龙江中医药大学中药系 中药化学专业学习，获硕士学位 1995.9- 1998.7 北京中医药大学中药学院 中药化学专业学习，获博士学位 1998.9- 2000.10 北京大学药学院 生药学专业博士后研究 2000年10月至今 北京大学药学院天然药物学系，先后任讲师和副教授，硕士研究生导师 2001.2- 2002.1 Eisai公司筑波薬物研究所（日本） 研修药用植物活性成分研究的新技术和新方法 2008.5 長崎国际大學（日本） 薬學部薬品资源學研究室 访问学者

研究领域

生物活性天然产物与创新药物研究；中药代谢与生物转化研究

近期论文

1)Cheng-Zhi Wang，Xiao-Qing Ma，Dong-Hui Yang* et al. Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria. BMC Microbiology 2010, 10: 115. (*为责任作者) 2)Xiao-Qing Ma, Wei-Feng Deng, Dong-Hui Yang * , Guang-Xue Liu, Hao Hong, Kuang-Nam Paek, Shao-Qing Cai. HPLC fingerprinting and quantification of gentiopicroside and loganic acid in Gentianae Macrophyllae Radix crude drugs. Journal of Chinese Pharmaceutical Sciences 2010, 19 (4): 243-250. 3)Pema Dolma, Dong-Hui Yang*, Jie Yu, Xuan Wang, Shao-Qing Cai. Pharmacokinetica studies of aristolochic acid-I and –II in rats after intragastrical administration of Radix Aristolochiae and Muskone. Journal of Chinese Pharmaceutical Sciences, 2009, 18: 55-59. 4)Jun-Ping Hu, Dong-Hui Yang, Wen-Han Lin, and Shao-Qing Cai, Alkaloids from the Roots of Stemona tuberosa. Helvetica Chimica Acta, 2009, 92, 2125-2133. 5) Lan-Lan Fan, Shu Zhu, Hu-Biao Chen, Dong-Hui Yang, Shao-Qing Cai, Katsuko Komatsu. Molecular analysis of stemona plants in china based on sequences of four Chloroplast DNA regions. Biol. Pharm. Bull., 2009，32 (8): 1439-1446. 6) Lan-Lan Fan, Shu Zhu, Hu-Biao Chen, Dong-Hui Yang, Shao-Qing Cai, Katsuko Komatsu Identification of the Botanical Source of Stemonae Radix Based on PCR with Specific Primers and PCR-RFLP. Biol. Pharm. Bull., 2009，32 (9): 1624-1627. 7) Bao-Song Cui, Xiao-Qing Ma, Dong-Hui Yang*, Xue-Qiao Hu, Shao-Qing Cai. Purification method of rohitukine from the stem bark of Dysoxylum binectariferum. Journal of Chinese Pharmaceutical Sciences, 2008, 17: 153-157. 8) Donghui Yang, Shaoqing Cai, Hongyu Liu, Xinxin Guo, Changling Li, Mingying Shang, Xuan Wang, Yuying Zhao. On-line identification of the constituents of Buyang Huanwu decoction in pig serum using combined HPLC-DAD-MS techniques. Journal of Chromatography B, 2006, 831: 288-302. 9) Feng Xu, Yue Zhang, Shengyuan Xiao, Xiaowei Lu, Donghui Yang, Xiaoda Yang, Changling Li, Mingying Shang, Pengfei Tu, and Shaoqing Cai. Absorption and Metabolism of Astragali Radix Decoction: In silico, in vitro, and a case study in vivo. Drug Metabolism and Disposition, 2006, 34: 913-924. 10)Dong Hui YANG, Shao Qing CAI, Yu Ying ZHAO, Hong LIANG. A New Alkaloid from Dysoxylum binectariferum. J. Asian Nat. Prod. Res., 2004, 6(3): 233-236. 11)Dong Hui YANG, Shao Qing CAI, Yu Ying ZHAO, Hong LIANG. Determination of the Absolute Configuration of Rohitukine. Chin. Chem. Lett., 2003, 14(7): 720-723