孙崎
近期热点
资料介绍
个人简历
1994.09~1998.07 北京医科大学药学院 本科 1998.09~2000.08 北京医科大学药学院学办 辅导员 2000.09~2005.07 北京大学药学院 硕士生、博士生 2005.08~2008.07 北京大学药学院 讲师 2008.10~2010.03 法国奥尔良大学ICOA 博士后(国家公派) 2013.12~2014.11 北京大学医学部设备与实验室管理处 副处长(挂职) 2015.03~ 北京大学医药卫生分析中心 常务副主任 2008.08~ 北京大学药学院 副教授、硕士生导师(2010年)研究领域
""致力于离子通道药物的设计、合成与活性评价工作,旨在针对神经系统疾病(如:认知障碍、焦虑症、抑郁症)和心血管系统疾病(如:房颤)开发出具有临床前景的新化学实体。""""近期论文
1. Songwen Lin, Yingbo Li, Yufen Zheng, Laichun Luo, Qi Sun*, Zemei Ge, Tieming Cheng and Runtao Li* Design, synthesis and biological evaluation of quinazoline–phosphoramidate mustard conjugates as anticancer drugs. Eur. J. Med. Chem. 2017, 127, 442 –458; 2. Dan Wan, Ding Wang, Qi Sun, Yan Song, Yimin Jiang, Runtao Li, Jia Ye*Antinociception of spirocyclopiperazinium salt compound LXM-10-M targeting α7 nicotinic receptor and M4 muscarinic receptor and inhibiting CaMKIIα/CREB/CGRP signaling pathway in mice. Eur. J. Pharmacol. 2016, 770, 92–98; 3.Yufen Zheng, Wenxing Zou, Laichun Luo, Jiabei Chen, Songwen LinandQi Sun* Ligand-free Cu-catalyzed O-arylation of aliphatic diols. RSC Adv. 2015, 5, 66104–66108; 4.You Wu,Yongning Xing, Jie Wang, Qi Sun*, Weiqi Kong, and Franck SuzenetPalladium-Catalyzed Desulfurative Sonogashira Cross-Coupling Reaction of 3-Cyano Assisted Thioamide-type Quinolone Derivatives with Alkynes. RSC Adv. 2015, 5, 48558–48562; 5. Laichun Luo, Lanlan Meng, Yangqiu Peng, Yongning Xing, Qi Sun*, Zemei Ge, and Runtao Li*ZnCl2-Promoted One-Pot Three-Component Synthesis of Multisubstituted Thiazolo[4,5-b]pyridines and Thieno[2,3-b:4,5-b’]dipyridines. Eur. J. Org. Chem. 2015, 631–637; 6. Weiwei Zhang, Qi Sun, Xiaoli Gao, Yimin Jiang, Runtao LiandJia Ye* Anti-Inflammation of Spirocyclopiperazinium Salt Compound LXM-10 Targeting α7 nAChR and M4 mAChR and Inhibiting JAK2/STAT3 Pathway in Rats. PLoS ONE2013, 8, 66895; 7.Dongmei Xiao, Liqiang Han, Qi Sun*, Qianxi Chen, Ningbo Gong, Yang Lv, Franck Suzenet, Gérald Guillaumet, Tieming ChengandRuntao Li* Copper-Mediated Synthesis of N-fused Heterocycles via Csp-S Coupling Reaction and 5-endo-dig Cyclization Sequence. RSC Adv.2012,2, 5054–5057; 8. Qi Sun, Franck Suzenet*andGérald Guillaumet Optimized Liebeskind-Srogl Coupling Reaction between Dihydropyrimidines and Tributyltin Compounds. Tetrahedron Lett. 2012, 53, 2694–2698; 9.Xia Zhao, Jia Ye*, Qi Sun, Yulan Xiong, Runtao LiandYimin Jiang Antinociceptive effect of spirocyclopiperazinium salt compound LXM-15 via activating peripheral α7 nAChR and M4 mAChR in mice. Neuropharmacology 2011, 60, 446–452; 10.Qi Sun, Franck Suzenet*andGérald GuillaumetDesulfitative Cross-Coupling of Protecting Group-Free 2-Thiouracil Derivatives with Organostannanes.J. Org. Chem.2010, 75, 3473–3476; 相关热点