近期论文

Campbell JD, McDonough JE, Zeskind JE, Pechkovsky DV, Brandsma C, Suzuki M., Gosselink JV, Liu G, Alekseyev YO, Xiao J., Zhang X., Hayashi S, Cooper JD, Timens W, Postma DS, Knight DA, Lenburg ME, Hogg JC, Spira A. (2011) The gene expression signature of emphysematous lung destruction in COPD is reversed by a potential novel therapeutic. Cancer Prev Res (submitted)
Beane J, Vick J, Anderlind C, Luo L, Zhang X, Xiao J, Alekseyev YO, Wang S, Levy S, Schembri F, Massion P, Lenburg M, Spira A (2011) Characterizing the impact of smoking and lung cancer on the airway transcriptome via RNA-seq. Cancer Prev Res (accepted)
Steiling K, Berge M, Sebastiani P, O’Connor G, Zhang X, Liu G, Xiao J, Alekseyev YO, Campbell J, Coxson HO, Hogg JC, McWilliams A, Timens W, Hiemstra PS, Sterk PJ, Sin D, Postma D, Lam S, Lenburg ME, Spira A. (2011) Airway Gene Expression as a Molecular Phenotype of COPD. Proc Am Thorac Soc. 8(2):208
Panchenko MP, Siddiquee Z, Dombkowski DM, Alekseyev YO, Lenburg ME, Walker JD, Macgillivray TE, Preffer FI, Stone JR (2010) Protein kinase CK1alphaLS promotes vascular cell proliferation and intimal hyperplasia. Am J Pathol. 177:1562-72
Zhang X, Liu G, Schembri F, Zhang X, Dumas YM, Langer EM, Alekseyev YO, O’Connor GT, Brooks DR, Sebastiani P, Lenburg ME, Spira A (2010) Similarity and differences in effect of cigarette smoking on gene expression in nasal and bronchial epithelium. Physiological Genomics. 41:1-8
Papageorgis P, Lambert A, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky H, Lenburg M, Thiagalingam S (2010) Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Research. 70:968-978.
Zhou J, Huang W, Tao R, Ibaragi S, Lan F, Ido Y, Wu X, Alekseyev YO, Lenburg ME, Hu GF, Luo Z. (2009) Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells. Oncogene, 28(18):1993-2002.
Neeley WL, Delaney S, Alekseyev YO, Jarosz DF, Delaney JC, Walker GC, and Essigmann JM (2007) DNA Polymerase V Allows Bypass of Toxic Guanine Oxidation Products. J. Biol. Chem., 282(17): 12741-8.
Alekseyev, Y. O., Hamm, M. L., and Essigmann, J. M. (2004) Aflatoxin B1 Formamidopyrimidine Adducts are Preferentially Repaired by Nucleotide Excision Repair Pathway In Vivo. Carcinogenesis, 25(6): 1-7.
Essigmann, J. M., Smela, M., Alekseyev, Y. O., and Allen, J.L.(2004) Aflatoxin B1: from Damage to Mutagenesis. In: Evolving Genetics and its Global Impact. 1: 131-133, Amarin Printing and Publishing Co, Ltd., Bangkok, Thailand
Alekseyev, Y. O. and Romano, L. J. (2002) Effects of Benzo[a]pyrene Adduct Stereochemistry on Downstream DNA Replication In Vitro: Evidence for Different Adduct Conformations within the Active Site of DNA Polymerase I (Klenow Fragment). Biochemistry 41(13): 4467-4479.
Dzantiev, L., Alekseyev , Y. O., Morales, J. C., Kool, E. T., and Romano, L. J. (2001) Significance of Hydrogen Bonding and Shape Complementarity for the Formation and Stability of the Closed Polymerase-DNA-dNTP Complex. Biochemistry 40(10): 3215-21.
Alekseyev, Y. O., Dzantiev, L., and Romano, L. J. (2001) Effects of (+)-anti-B[a]PDE Adducts on Escherichia coli DNA Polymerase I (Klenow fragment) Primer-Template binding: Evidence for Inhibition of the Catalytically Active Ternary Complex Formation. Biochemistry 40(7): 2282-90.
Alekseyev, Y. O. and Romano, L. J. (2000) In vitro Replication of Primer-Templates Containing Benzo[a]pyrene Adducts by Exonuclease-deficient Escherichia coli DNA Polymerase I (Klenow Fragment): Effect of Sequence Context on Lesion Bypass. Biochemistry 39(34): 10431-10438.
Tonevitsky, A. G., Rakhmanova, V. A., Agapov, I. I., Shamshiev, A. T., Usacheva, E. A, Prokoph’ev, S. A., Denisenko, O. N., Alekseyev, Y. O., and Pfueller, U. (1995) The Interactions of Anti-MLI Monoclonal Antibodies with Isoforms of the Lectin from Viscum album. Immunol Lett. 44(1): 31-4.
Tonevitsky, A. G., Toptygin, A. Yu., Agapov, I. I., Rakhmanova, V. A., Shamshiev, A. T., Alekseyev, Y. O., Pfueller, U., and Frankel, A. (1995) Production of Biologically Active Recombinant Ricin B-Chain. Mol Biol (Mosk) 29(2): 398-406.
Tonevitsky, A. G., Alekseyev, Y. O., Temiakov, D. E., Shamshiev, A. T., and Agapov, I. I. (1995) Interaction of Isoforms of Lectin from Viscum album with Monoclonal Antibody against a Catalitic Subunit. Biotechnology (11): 25-31.
Tonevitsky, A. G., Temiakov, D. E., Moisenovich, M. M., Shamshiev, A. T., Agapov, I. I., Alekseyev, Y. O., Egorova, S. G., and Kharitonenkov, I. G. (1995) Cytotoxic Activity of the Immunotoxin on the Basis of the Catalitic Subunits of Ricin and Ricin Agglutinin and Monoclonal Antibody to 35 KDa Antigen of Human Melanoma. Biotechnology (11): 31-35.
Tonevitsky, A. G., Alekseyev, Y. O., Shamshiev, A. T., Ryzhavskaya, A. S., Temiakov, D. E., and Agapov, I. I. (1995) Study of Changes in the Structure of the Plant Toxin MLI during the Adsorption on Immunological Plate and after a Treatment with Various Denaturation Agents with the Help of Monoclonal Antibodies. Biotechnology (11): 35-40.