个人简历

2016年1月至今 四川大学生物治疗国家重点实验室教授 2014年1月-2016年1月 清华大学医学院博士后 2010年9月-2014年1月 清华大学生命科学学院博士

研究领域

真核生物膜转运蛋白的结构生物学研究 药物分子跨膜转运的分子机制研究 肿瘤等疾病中物质跨膜转运机制研究 囊泡神经递质转运的分子机制研究

近期论文

1. Deng, D.*, Sun, P.*, Yan, C., Ke, M., Jiang, X., Ren, W., Hirata, K., Yamamoto, M., Fan, S., & Yan, N. (2015). Molecular basis of ligand recognition and transport by glucose transporters. Nature, 526，391-396. (*, co-first author) 2. Deng, D.*, Xu, C.*, Sun, P.*, Wu, J.*, Yan, C., Hu, M., & Yan, N. (2014). Crystal structure of the human glucose transporter GLUT1. Nature, 510, 121-125. (*, co-first author) 3. Deng, D.*, Yan, C.*, Pan, X.*, Mahfouz, M., Wang, J., Zhu, J. K., Shi, Y., & Yan, N. (2012). Structural basis for sequence-specific recognition of DNA by TAL effectors. Science, 335, 720-723. (*, co-first author) 4. Deng, D., Yan, C., Wu, J., Pan, X., & Yan, N. (2014). Revisiting the TALE repeat. Protein & cell, 5, 297-306. 5. Yin, P.*, Deng, D.*, Yan, C., Pan, X., Xi, J. J., Yan, N., & Shi, Y. (2012). Specific DNA-RNA hybrid recognition by TAL effectors. Cell reports, 2, 707-713. (*, co-first author) 6. Deng, D.*, Yin, P.*, Yan, C., Pan, X., Gong, X., Qi, S., Xie, T., Mahfouz, M. Zhu, J. K., Yan, N., & Shi, Y. (2012). Recognition of methylated DNA by TAL effectors. Cell research, 22, 1502-1504. (*, co-first author) 7. Deng, D. & Yan, N. (2016) GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters. Protein Sci. 25, 546–58.