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杨恒文
2023-05-22 14:48
  • 杨恒文
  • 杨恒文 - 副研究员-暨南大学-生物医学转化研究院-个人资料

近期热点

资料介绍

个人简历


教育背景
1997.9-2001.6 学士, 清华大学生物科学与技术系(现生命科学院)。
2001.9-2007.1 博士,导师:陈应华教授。清华大学生物科学与技术系(现生命科学院)。
工作背景
2007.1-2013.6 博士后/研究助理;美国科罗拉多大学博尔德校区,导师: Ding Xue
2013.7-至今: 副研究员,院长助理。暨南大学生物医学转化研究院

研究领域


1. 肠道微生物与免疫系统的相互调控;
2. 代谢性疾病的免疫机制;
3. 基于动物模型(线虫、小鼠)的小分子药物筛选

近期论文


[1] Guangchao Cao#, Qian Wang#, Wanjun Huang#, Jiyu Tong, Dewei Ye, Yan He, Zonghua Liu, Xin Tang, Hao Cheng, Qiong Wen, Dehai Li, Hau-Tak Chau, Yiming Wen, Hui Zhong, Ziyu Meng, Hui Liu, Zhenzhou Wu, Liqing Zhao, Richard A Flavell, Hongwei Zhou, Aimin Xu, Hengwen Yang*, Zhinan Yin*. Long-term consumption of caffeine-free high sucrose cola beverages aggravates the pathogenesis of EAE in mice. Cell Discovery (2017) 3, 17020; doi:10.1038/celldisc.2017.20(Co-corresponding author)
[2] Liu J#, Yang H#, Yin Z, Jiang X, Zhong H, Qiu D, Zhu F, Li R. Remodeling of the gut microbiota and structural shifts in Preeclampsia patients in South China. Eur J Clin Microbiol Infect Dis. 2017 Apr;36(4):713-719, doi: 10.1007/s10096-016-2853-z.(IF=2.857, Co-first author)
[3] Yang Hengwen#, Chen YZ#, Zhang Y#, Wang X, Zhao X, Godfroy JI 3rd, Liang Q, Zhang M, Zhang T, Yuan Q, Ann Royal M, Driscoll M, Xia NS, Yin H, Xue D. A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells. Nature Communications. 2015 Jan 7; 6:5717. (IF=11.47)
[4] Chao L#, Lu L#, Yang Hengwen#, Zhu Y, Li Y, Wang Q, Yu X, Jiang S, Chen YH*. Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure. PLoS One. 2013 May 31;8(5): e66156. (IF=3.53, Co-first author)
[5] Hengwen Yang, Canhui Lan, Ying-Hua Chen. Evidence for existence of a close association between CD14 and CXCR4 on monocytic cell line U937. Porgress in Natural Science. 2007 (IF=0.57)
[6] Hengwen Yang, Canhui Lan, Yi Xiao, Ying-Hua Chen. Antibody to CD14 like CXCR4-specific antibody 12G5 could inhibit CXCR4-dependent chemotaxis and HIV Env-mediated cell fusion. Immunol Lett. 2003, 88 (1): 27-30. (IF=2.36)
[7] Hengwen Yang, Yi Xiao, Yun Lu, Ying-Hua Chen. Characterization of interaction between C-domain on HIV-1 gp41 and the putative receptor protein p62. Immunobiology. 2001, 203: 778-785. (IF=3.18)

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