个人简历

个人简介：
博士毕业于第三军医大学，博士期间主要从事肺癌和乳腺癌发病机制研究工作，发现了Wnt/β-catenin通路在肺癌中的新的调控机制，该通路在胚胎发育，肿瘤发生以及肺纤维化中发挥关键功能。
博士毕业后于美国希望城国家医学中心从事DNA损伤修复与肺癌发生关系的研究。
2018年7月进入河南师范大学生命科学学院工作，从事肺纤维化发病机理的研究。目前总计发表SCI论文7篇，其中5分以上5篇，第一作者3篇（＞5分1篇），共同第一作者1篇（＞5分）。
主持或参加科研项目情况：
1.河南省高等学校重点科研项目（20A310006）2019-2021
2.河南师范大学博士科研启动基金（5101049170182）2019-2022

近期论文

1.TangCZ#,YangJT#（共同第一）,LiuQH,WangYR,WangWS:Up-regulatedmiR-192-5pexpressionrescuescognitiveimpairmentandrestoresneuralfunctioninmicewithdepressionviatheFbln2-mediatedTGF-beta1signalingpathway.FASEBjournal(IF=5.595):officialpublicationoftheFederationofAmericanSocietiesforExperimentalBiology2019,33(1):606-618.
2.TangCZ,ZhangDF,YangJT,LiuQH,WangYR,WangWS.OverexpressionofmicroRNA-301baccelerateshippocampalmicrogliaactivationandcognitiveimpairmentinmicewithdepressive-likebehaviorthroughtheNF-κBsignalingpathway.CellDeathDis(IF=5.638).2019Apr8;10(4):316.doi:10.1038/s41419-019-1522-4.
3.HanF,LiuWB,LiJJ,ZhangMQ,YangJT,ZhangX,HaoXL,YinL,MaoCY,JiangXetal:SOX30isaprognosticbiomarkerandchemotherapeuticindicatorforadvanced-stageovariancancer.Endocrine-relatedcancer(IF=5.331)2019.
4.HanF,LiuWB,ShiXY,YangJT,ZhangX,LiZM,JiangX,YinL,LiJJ,HuangCSetal:SOX30InhibitsTumorMetastasisthroughAttenuatingWnt-SignalingviaTranscriptionalandPosttranslationalRegulationofbeta-CatenininLungCancer.EBioMedicine(IF=6.138)2018,31:253-266.
5.YangJ,HanF,LiuW,ChenH,HaoX,JiangX,YinL,HuangY,CaoJ,ZhangHetal:ALX4,anepigeneticallydownregulatedtumorsuppressor,inhibitsbreastcancerprogressionbyinterferingWnt/beta-cateninpathway.Journalofexperimental&clinicalcancerresearch:CR(IF=6.217)2017,36(1):170.
6.YangJ,HanF,LiuW,ZhangM,HuangY,HaoX,JiangX,YinL,ChenH,CaoJetal:LHX6,AnIndependentPrognosticFactor,InhibitsLungAdenocarcinomaProgressionthroughTranscriptionalSilencingofbeta-catenin.JournalofCancer2017(IF=3.2),8(13):2561-2574.
7.YangJ,WangR,LiuB,XueQ,ZhongM,ZengH,ZhangH:KineticanalysisofbypassofabasicsitebythecatalyticcoreofyeastDNApolymeraseeta.MutationResearch/FundamentalandMolecularMechanismsofMutagenesis(IF=2.5)2015,779:134-143.
8.YuGY,YangJT,ZhaoWM,GuoXS.RoleofHMSG2MediatedFAODeficiencyinIPFPathogenesis.AJRCCM-conference.2019.199.A5232
9.YuGY,YangJT,ZhaoWM,IberraG,ChenX,GuoXS,Kaminski.N.RoleofTerraonTelomericandMitochondrialFunctionsinIPFPathogenesis.AJRCCM-conference.2019.199.A1045