个人简历

1957年生，1987年获湖南大学分析化学博士学位，1989-1991年在瑞士苏黎世联邦高等理工学院（ETH）进行博士后研究。1992年晋升为湖南大学教授。他是国家杰出青年基金获得者（1998）、国家自然科学基金委化学科学部专家咨询委员会委员（2008至今）、专家评审组成员（2010年至今）、《The Analyst》顾问编委、《高等学校化学学报》副主编、《中国化学快报》副主编，以第一完成人获2011年国家自然科学二等奖、2009年湖南省自然科学一等奖、2003年湖南省科技进步一等奖等多项奖励。

研究领域

"""""纳米及分子水平上的生物分析化学、分子工程、纳米生物医学器件、化学与生物传感器"

近期论文

Fengzhou Xu†, Lan Luo†, Hui Shi*, Xiaoxiao He, Yanli Lei, Jinlu Tang, Dinggeng He, Zhenzhen Qiao and Kemin Wang*, Label-free and sensitive microRNA detection based on a target recycling amplification-integrated superlong poly(thymine)-hosted copper nanoparticle strategy, Analytica Chimica Acta, 2018, 1010, 54-61. DOI: doi.org/10.1016/j.aca.2018.01.010.r
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Yan Zheng, Qing Wang*, Xiaohai Yang, Wenyan Nie, Liyuan Zou, Xiaofeng Liu, and Kemin Wang*, “Aptamer as a Tool for Investigating the Effects of Electric Field on Aβ40 Monomer and Aggregates Using Single Molecule Force Spectroscopy”, Analytical Chemistry. DOI: 10.1021/acs.analchem.8b04278 (2018)r
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Hongmei Fang†, Nuli Xie†, Min Ou, Jin Huang, Wenshan Li, Qing Wang, Jianbo Liu, Xiaohai Yang*, and Kemin Wang*, Detection of Nucleic Acids in Complex Samples via Magnetic Microbead-Assisted Catalyzed Hairpin Assembly and “DD–A” FRET,Analytical Chemistry 90 (12), 7164-7170 (2018). DOI: 10.1021/acs.analchem.8b01330 r
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Baoyin Yuan, Yuanyuan Chen, Yuqiong Sun, Qiuping Guo*, Jin Huang, Jianbo Liu, Xiangxian Meng, Xiaohai Yang, Xiaohong Wen, Zenghui Li, Lie Li, and Kemin Wang*, Enhanced Imaging of Specific Cell-Surface Glycosylation Based on Multi-FRET,Analytical Chemistry 90 (10), 6131-6137 (2018). DOI: 10.1021/acs.analchem.8b00424r
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Wenjie Ma, Lv’an Yan, Xiaoxiao He*, Taiping Qing, Yanli Lei, Zhenzhen Qiao, Dinggeng He, Kaihang Huang, Kemin Wang*, Hairpin-Contained i-Motif Based Fluorescent Ratiometric Probe for High-Resolution and Sensitive Response of Small pH Variations, Analytical Chemistry, 2018, 90(3), 1889-1896.DOI: 10.1021/acs.analchem.7b03972 r
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Hong Cheng, Jinquan Liu, Wenjie Ma, Shuangdi Duan, Jin Huang, Xiaoxiao He*, and Kemin Wang*, Low Background Cascade Signal Amplification Electrochemical Sensing Platform for Tumor-Related mRNA Quantification by Target-Activated Hybridization Chain Reaction and Electroactive Cargo Release, Analytical Chemistry 90 (21), 12544-12552 (2018). DOI:10.1021/acs.analchem.8b02470 r
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Wenyan Nie, Qing Wang*, Liyuan Zou, Yan Zheng, Xiaofeng Liu, Xiaohai Yang, and Kemin Wang*, Low-Fouling Surface Plasmon Resonance Sensor for Highly Sensitive Detection of MicroRNA in a Complex Matrix Based on the DNA Tetrahedron, Analytical Chemistry 90 (21), 12584-12591 (2018).DOI: 10.1021/acs.analchem.8b02686 r
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Xiaofeng Liu‡, Hua Zhang‡, Shiya Qin, Qing Wang*, Xiaohai Yang, Kemin Wang*, Optical fiber amplifier for quantitative and sensitive point-of-care testing of myoglobin and miRNA-141, Biosensors and Bioelectronics, 2018, Ms. Ref. No.: BIOS-D-18-03867R1 r
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Duo Li†, Zhenzhen Qiao†, Yanru Yu, Jinlu Tang, Xiaoxiao He, Hui Shi*, Xiaosheng Ye, Yanli Lei and Kemin Wang*. In situ fluorescence activation of DNA-silver nanoclusters as a label-free and general strategy for cell nucleus imaging, Chemical Communication, 2018, 54(9), 1089-1092. DOI: 10.1039/c7cc08228br
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Yanli Lei, Xiaoxiao He, Jinlu Tang, Hui Shi*, Dinggeng He, Lv An Yan, Jianbo Liu, Yu Zeng, and Kemin Wang*, Ultra-pH-responsive split i-motif based aptamer anchoring strategy for specific activatable imaging of acidic tumor microenvironment, Chemical Communications 54 (73), 10288-10291 (2018). DOI: 10.1039/c8cc04420ar
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Jiaoli Wang, Jin Huang*, Ke Quan, Jing Li, Yanan Wu, Qiaomei Wei, Xiaohai Yang, and Kemin Wang*, Hairpin-fuelled catalytic nanobeacons for amplified microRNA imaging in live cells, Chemical Communications 54 (73), 10336-10339 (2018). DOI: 10.1039/c8cc06298fr
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Qiaomei Wei, Jin Huang*, Jing Li, Jiaoli Wang, Xiaohai Yang, Jianbo Liu, and Kemin Wang*, A DNA nanowire based localized catalytic hairpin assembly reaction for microRNA imaging in live cells, Chemical Science 9 (40), 7802-7808 (2018).DOI: 10.1039/C8SC02943Ar
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Ke Quan, Jing Li, Jiaoli Wang, Nuli Xie, Qiaomei Wei, Jinlu Tang, Xiaohai Yang, Kemin Wang, and Jin Huang*, Dual-MicroRNA-Controlled Double-Amplified Cascaded Logic DNA Circuits for Cell Subtypes Accurate Discrimination, Chemical Science DOI: 10.1039/C8SC04887H (2019).r
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Lin Lan, Qiuping Guo, Hemin Nie, Chang Zhou, Qingyun Cai, Jin Huang* and Xiangxian Meng*, Linear-hairpin variable primer RT-qPCR for MicroRNA, Chemical Science DOI: 10.1039/c8sc04621b, (2019).r
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Li Li†, Gui Li†, Xiaoxiao He, Xiaohai Yang, Songyang Liu, Jinlu Tang, Qiaoshu Chen, Jianbo Liu*, and Kemin Wang*, Protein- driven disassembly of surfactant- polyelectrolyte nanomicelles: Modulation of quantum dot/fluorochrome FRET for pattern sensing, Sensors and Actuators B: Chemical 272, 393-399 (2018).DOI: doi.org/10.1016/j.snb.2018.05.130r
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Yanli Lei, Zhenzhen Qiao, Jinlu Tang, Xiaoxiao He, Hui Shi*, Xiaosheng Ye, Lv'an Yan, Dinggeng He, and Kemin Wang*, DNA nanotriangle-scaffolded activatable aptamer probe with ultralow background and robust stability for cancer theranostics, Theranostics 8 (15), 4062-4071 (2018).DOI: 10.7150/thno.24683r
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Le Ying, Nuli Xie, Yanjing Yang, Xiaohai Yang, Qifeng Zhou, Bincheng Yin, Jin Huang,* and Kemin Wang*.A cell-surface-anchored ratiometric i-motif sensor for extracellular pH detection,Chem. Commun. 2016, 52, 7818-7821 . DOI: 10.1039/C6CC03163C r
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Jin Huang, He Wang, Xiaohai Yang, Yanjing Yang, Ke Quan, Le Ying, Nuli Xie, Min Ou, and Kemin Wang,Fluorescence resonance energy transfer-based hybridization chain reaction for in situvisualization of tumor-related mRNA,Chem. Sci. 2016, 7, 3829-3835. DOI: 10.1039/C6SC00377J r
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Nandi Chen, Xiaohai Yang,* Qing Wang, Lixin Jian, Hui Shi, Shiya Qin, Kemin Wang,* Jin Huang and Wenjing Liu. Proof of concept for inhibiting metastasis: circulating tumor cell-triggered localized release of anticancer agent via a structure-switching aptamer. Chem. Commun., 2016, 52, 6789-6792. DOI: 10.1039/C6CC02374F r
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Baoyin Yuan, Yu Zhou, Qiuping Guo,* Kemin Wang,* Xiaohai Yang, Xiangxian Meng, Jun Wan, Yuyu Tan, Zhixiang Huang, Qin Xie and Xiayu Zhao. A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET. Chem. Commun., 2016, 52, 1590-1593. DOI: 10.1039/C5CC08060F