洪明
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洪明,2008年进入军事医学科学院基础医学研究所学习,师从徐东刚教授,研究领域涉及分子遗传学,分子诊断。2011 年遗传学硕士毕业后在华大基因分子诊断中心从事肿瘤分子诊断研究。2013年进入香港大学中医药学院攻读中药药理学博士学位,主要研究中药抗肿瘤活性及其分子机制。2017年10月博士毕业进入广州中医药大学临床药理研究所,任副研究员。本课题小组综合利用网络药理学,分子对接技术以及体内,体外试验预测中药的抗肿瘤活性成分及其分子机制。已累计发表第一及通讯作者SCI论文9篇。本课题小组与香港大学中医药学院保持良好的合作关系,学生在硕士期间可获得与香港大学联合培养的学习机会(在香港学习期间可从本人科研经费中给予一定的经济补助),优秀硕士毕业生可获得推荐,继续攻读香港大学博士学位。教育背景2013/07-2017/09,香港大学,中医药学院,博士,导师:冯奕斌2008/09-2011/06,军事医学科学院,基础医学研究所,硕士,导师:徐东刚2004/09-2008/06,江西中医学院,生物工程系,本科,学士工作经历2017/11-至今,广州中医药大学,临床药理研究所,副研究员2013/01-2013/05,香港大学,解剖系,研究助理2012/04-2012/10, 浙江大学科技园分子诊断中心,研究助理2011/07-2011/12, 华大基因, 临床分子诊断中心,肿瘤分子诊断高级专员主要荣誉多次受邀参加本学科领域内知名国际会议并发表以下会议报告:Ming Hong,Yibin Feng. A biomedical investigation on the hepatoprotective effect of Coriolus versicolor L and Salvia miltiorrhiza Bge, International Conference and Exhibition on July 25-27, 2016 Melbourne, Australia.Ming HONG, Ning WANG, Yibin FENG*. The Inhibitory Effect of Scutellaria Baicalensis and Wogonoside by Inhibiting the Activity of Matrix Metalloproteinase-9 in Hepatocarcinoma: An in vitro Biomedical Investigation Integrated with Molecular Docking. The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, 2017, Hong Kong. 科研项目基于网络药理学,分子对接技术以及体内体外试验预测黄芩的抗肿瘤活性成分及其分子机制。广州中医药大学杏林后备人才科研启动基金(50万)。研究领域
目前主要从事中药抗肿瘤药理学机制的研究。"中药药理学"近期论文
[1] Hong M, Zha L, Fu W, Zou M, Li W, Xu D. A modified visual loop-mediated isothermal amplification method for diagnosis and differentiation of main pathogens from Mycobacterium tuberculosis complex. World J Microbiol Biotechnol, 2012. 28(2): p. 523-31.[2] Hong M, Wang N, Tan HY, Tsao SW, Feng Y. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy. Cancers (Basel), 2015. 7(3): p. 1643-57.[3] Hong M, Li S, Tan HY, Wang N, Tsao SW, Feng Y. Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects. Int J Mol Sci, 2015. 16(12): p. 28705-45[4] Hong M, Tan HY, Li S, Cheung F, Wang N Nagamatsu T, Feng Y. Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds. Int J Mol Sci, 2016. 17(6).[5] Hong M, Li S, Wang N, Tan HY, Cheung F, Feng Y. A Biomedical Investigation on the Hepatoprotective Effect of Radix Salviae Miltiorrhizae and Network pharmacology-based Prediction of the Active compunds and Molecular Targets. Int J Mol Sci Int. J. Mol. Sci. 2017, 18(3), 620; doi:10.3390/ijms18030620.[6] Hong M, Li S, Tan HY, Cheung F, Wang N, Huang J, Feng Y. A Network-Based Pharmacology Study of the Herb-Induced Liver Injury Potential of Traditional Hepatoprotective Chinese Herbal Medicines. Molecules 2017, 22(4), 632; doi:10.3390/molecules22040632[7] Ming Hong, Yongsheng Zhang, Sha Li, Hor Yue Tan, Ning Wang, Shuzhen Mu, Xiaojiang Hao,Yibin Feng. A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae Molecules 2017, 22(10), 1617; doi:10.3390/molecules22101617.[8] Ming Hong*, Honghui Cheng#, Lei Song, Wencai Wang, Qi Wang, Donggang Xu and Weiwei Xing*. Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. Molecules 2018, 23(2), 384; doi:10.3390/molecules23020384.[9] Ming Hong*, Zhe Cai#, Lei Song, Yongqiang Liu, Qi Wang* and Xiangfei Feng*. Gynostemma pentaphyllum attenuates the progression of Non-alcoholic fatty liver disease in Mice: a biomedical investigation integrated with in silico assay. Evidence-Based Complementary and Alternative Medicine. Volume 2018, Article ID 8384631, 13 pages. 相关热点
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