个人简历

學歷
民國87年，台灣大學化學系學士
民國89年，台灣大學化學系碩士
民國97年，美國聖路易華盛頓大學博士
經歷
民國97年8月,美國聖路易華盛頓大學 博士後研究
民國98年1月,美國哈佛大學 博士後研究
民國102年11月迄今，中央研究院原子與分子科學研究所助研究員
榮譽及獎項
2017 年輕學者創新獎，傑出人才基金會
2009 Fellowship, Postdoctoral Research Abroad Program, National Science Council, Taiwan.
2008 Student Award, The 49th Experimental Nuclear Magnetic Resonance Conference
2004 TA Teaching Award, Washington University in St. Louis
研究成果
The study of HIV-1 Vpr-membrane and Vpr-hVDAC-1 interactions by Graphene Field-Effect Transistor Biosensors
Biophysical characterization and modulation of Transthyretin Ala97Ser
Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR
Photochemistry of Bacteriorhodopsin with Various Oligomeric Statuses in Controlled Membrane Mimicking Environments: A Spectroscopic Study from Femtoseconds to Milliseconds
Highly Efficient Transfer of 7TM Membrane Protein from Native Membrane to Covalently Circularized Nanodisc
Membrane Charging and Swelling upon Calcium Adsorption as Revealed by Phospholipid Nanodiscs

研究领域

1. 膜蛋白研究
2. 核磁共振光譜學
3. 家族性類澱粉沉積症的基礎研究""

近期论文

1. Vivien Yeh, Tsung-Yen Lee, Chung-Wen Chen, Pai-Chia Kuo, Jessie Shiue, Li-Kang Chu,* and Tsyr-Yan Yu*
Highly Efficient Transfer of 7TM Membrane Protein from Native Membrane to Covalently Circularized Nanodisc, Scientific Reports, 2018, 8, 13501. DOI: 10.1038/s41598-018-31925-1
2. Orion Shih, Yi-Qi Yeh, Kuei-Fen Liao, Chun-Jen Su, Pei-Hao Wu, Richard K. Heenan, Tsyr-Yan Yu*, and U-Ser Jeng*
Membrane Charging and Swelling upon Calcium Adsorption as Revealed by Phospholipid Nanodiscs, Journal of Physical Chemistry Letters, 2018, 9, 4287.
3. Yustina Yusuf, Julien Massiot, Yu-Ting Chang, Pei-Hao Wu, Vivien Yeh, Pai-Chia Kuo, Jessie Shiue*, Tsyr-Yan Yu*
Optimization of the production of covalently circularized nanodiscs and their characterization in physiological conditions, Langmuir, 2018, 34, 3525.
4. Vivien Yeh, Yin Hsin, Tsung-Yen Lee, Jerry Chun Chung Chan, Tsyr-Yan Yu*, and Li-Kang Chu*
Lipids Influence the Proton Pump Activity of Photosynthetic Protein Embedded in Nanodiscs, RCS Advances 2016, 6, 88300-88305.
5. Tsung-Yen Lee, Vivien Yeh, Julia Chuang, Jerry Chun Chung Chan, Li-Kang Chu, Tsyr-Yan Yu*,
Tuning the Photocycle Kinetics of Bacteriorhodopsin in Lipid Nanodiscs, Biophys. J. 2015; 109(9), 1899-1906.
6. Matthew T Eddy, Tsyr-Yan Yu*, Membranes, Peptides, and Disease: Unraveling the Mechanisms of Viral Proteins with Solid State Nuclear Magnetic Resonance Spectroscopy. Solid State Nuclear Magnetic Resonance 2014; 61-62, 1-7.