张丹丹
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个人简历
张丹丹,女,1986年生,山东烟台人。博士,副研究员,中国科协“青年人才托举工程”入选者。主持国家自然科学基金面上和青年项目、国家重点研发计划子课题、青年人才托举工程等项目4项。近5年以第一(共一)作者在New Phytologist、Molecular Plant Pathology等期刊发表学术论文11篇,授权专利4件。参与完成首株来源棉花大丽轮枝菌全基因组解析工作,通过比较基因组分析阐明了大丽轮枝菌寄主广谱与专化协同进化的遗传变异机制;发现了强致病力落叶型大丽轮枝菌通过水平转移从棉花枯萎病菌获得基因簇参与脂质化合物 N -酰基乙醇胺合成以引起植物落叶的分子新机制;开展大丽轮枝菌胞外蛋白的毒力组分鉴定工作,明确了转录因子和囊泡蛋白调控蛋白分泌的过程与特性,鉴定出激活免疫反应的效应子,解析了多个细胞壁降解酶兼具毒力和激发寄主免疫反应的双重功能。研究领域
主要从事黄萎病防治基础研究,研究方向为大丽轮枝菌功能基因组学及其为害的分子基础。""近期论文
Zhang DD, Wang J, Wang D, Kong ZQ, Zhou L, Zhang GY, Gui YJ, Li JJ, HuangJQ, Wang BL, Liu C, Yin CM, Li RX, Li TG, Wang JL, Short DPG, KlostermanSJ, Bostock RM, Subbarao KV, Chen JY, Dai XF. Population genomics demystifies the defoliation phenotype in the plant pathogen Verticillium dahliae . New Phytol . 2019, 222: 1012–1029. doi: 10.1111/nph.15672. Epub 2019 Feb 25. (First Author)Chen JY, Liu C, Gui YJ, Si KW, Zhang DD, Wang J, Short DPG, Huang JQ, Li NY, Liang Y, Zhang WQ, Yang L, Ma XF, Li TG, Zhou L, Wang BL, Bao YM, Subbarao KV, Zhang GY, Dai XF. Comparative genomics reveals cottonspecific virulence factors in flexible genomic regions in Verticillium dahliae and evidence of horizontal gene transfer from Fusarium . New Phytol . 2018, 217(2):756770. doi: 10.1111/nph.14861. Epub 2017 Oct 30. (Cofirst Author)Wang D, Tian L, Zhang DD, Song J, Song SS, Yin CM, Zhou L, Liu Y, Wang BL, Kong ZQ, Klosterman SJ, Li JJ, Wang J, Li TG, Adamu S, Subbarao KV, Chen JY, Dai XF. Functional analyses of small secreted cysteinerich proteins identified candidate effectors in Verticillium dahliae . Mol Plant Pathol . 2020,21(5):667685. doi: 10.1111/mpp.12921. Epub 2020 Mar 10. (Cofirst Author)Gui YJ, Zhang WQ, Zhang DD, Zhou L, Short DPG, Wang J, Ma XF, Li TG, Kong ZQ, Wang BL, Wang D, Li NY, Subbarao KV, Chen JY, Dai XF. A Verticillium dahliae extracellular cutinase modulates plant immune responses. Mol Plant Microbe Interact . 2018, 31(2):260273. doi: 10.1094/MPMI06170136R. Epub 2017 Dec 20. (Cofirst Author)Wang D, Tian L, Zhang DD, Song J, Song SS, Yin CM, Zhou L, Liu Y, Wang BL, Kong ZQ, Klosterman SJ, Li JJ, Wang J, Li TG, Adamu S, Subbarao KV, Chen JY, Dai XF. Functional analyses of small secreted cysteine‐rich proteins identified candidate effectors in Verticillium dahlia e . Mol Plant Microbe Interact . 2020, 21(5):667685. doi.org/10.1111/mpp.12921. Epub 2020 March 10. (Cofirst Author)Chen JY, Zhang DD, Huang JQ, Wang D, Hao SJ, Li R, Puri KD, Yang Y, Bang Tong BZ, Xiong KX, Simko I, Klosterman SJ, Subbarao KV, Dai XF. Genome Sequence of Verticillium dahliae Race 1 isolate VdLs.16 from Lettuce. Mol Plant Microbe Interact . 2020, 33(11):12651269. doi: 10.1094/MPMI04200103A. (Cofirst Author)Wang J, Tian L, Zhang DD, Short DPG, Zhou L, Song SS, Liu Y, Wang D, Kong ZQ, Cui WY, Ma XF, Klosterman SJ, Subbarao KV, Chen JY, Dai XF. SNARE encoding genes VdSec22 and VdSso1 mediate protein secretion required for full virulence in Verticillium dahliae . Mol Plant Microbe Interact . 2018, 31(6):651664. doi: 10.1094/MPMI12170289R. Epub 2018 May 4. (Cofirst Author)Li TG, Wang BL, Yin CM, Zhang DD, Wang D, Song J, Zhou L, Kong ZQ, Klosterman SJ, Li JJ, Adamu S, Li Liu TL, Subbarao KV, Chen JY, Dai XF. The Gossypium hirsutum TIRNBSLRR gene GhDSC1 mediates resistance against Verticillium wilt. Mol Plant Pathol . 2019, 20(6):857–876. doi: 10.1111/mpp.12797. Epub 2019 Apr 8. (Cofirst Author)Li TG, Zhang DD, Zhou L, Kong ZQ, Hussaini AS, Wang D, Li JJ, Short DPG, Dhar N, Klosterman SJ, Wang BL, Yin CM, Subbarao KV, Chen JY and Dai XF. Genomewide identification and functional analyses of the CRK gene family incotton reveals GbCRK18 confers Verticillium Wilt resistance in Gossypium barbadense . Front. Plant Sci . 2018. 9:1266. doi: 10.3389/fpls.2018.01266. Epub 2018 Sep 11. (Cofirst Author)Zhang DD, Wang XY, Chen JY, Kong ZQ, Gui YJ, Li NY, Bao YM, Dai XF. Identification and characterization of a pathogenicityrelated gene VdCYP1 from Verticillium dahliae . Sci Rep. 2016, 6:27979. doi: 10.1038/srep27979. (First Author)Li NY, Zhou L, Zhang DD, Klosterman SJ, Li TG, Gui YJ, Kong ZQ, Ma XF, Short DPG, Zhang WQ, Li JJ, Subbarao KV, Chen JY, Dai XF. Heterologous expression of the cotton NBSLRR gene GbaNA1 enhances Verticillium wilt resistance in Arabidopsis. Front Plant Sci. 2018, Feb 6;9:119. doi: 10.3389/fpls.2018.00119A. (Cofirst Author)标签:
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