个人简历

教育经历\r
2006.09 - 2011.06 中国科学院上海应用物理所 博士\r
2000.09 - 2004.07 中国科学技术大学 学士\r
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工作经历\r
2015.10 - 至今 中山大学药学院教授\r
2011.07 - 2015.10 美国康奈尔大学医学院HMRI博士后

研究领域

"""""高通量微流控芯片用于液体活检和单细胞分析；框架核酸材料在分析方法学中的应用；多功能纳米材料用于癌症的诊断和治疗"

近期论文

Zhun Lin, Zhengyu Zou, Zhe Pu, Minhao Wu*,Yuanqing Zhang*. Application of Microfluidic Technologies on COVID-19 Diagnosis and Drug Discovery.Acta Pharmaceutica Sinica B. 2023; ASAP.\r
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Jizhou Tan, Ting Liu, Wenzhe Fan, Jialiang Wei, Bowen Zhu, Yafang Liu, Lingwei Liu, Xiaokai Zhang, Songling Chen, Haibiao Linc, Yuanqing Zhang*, Jiaping Li*. Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+ cells elimination in hepatocellular carcinoma. Acta Pharmaceutica Sinica B. 2023; ASAP.\r
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Lingwei Liu, Jialang Zhuang, Jizhou Tan, Ting Liu, Wenzhe Fan, Yuanqing Zhang*, and Jiaping Li*. Doxorubicin-Loaded UiO-66/Bi2S3 Nanocomposite-Enhanced Synergistic Transarterial Chemoembolization and Photothermal Therapy against Hepatocellular Carcinoma. ACS Applied Materials & Interfaces. 2022, 14, 6, 7579–7591.\r
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Yan Liu, Zhun Lin, Ziwei Zheng, Yuanqing Zhang*, Lingling Shui*. Accurate Isolation of Circulating Tumor Cells via a Heterovalent DNA Framework Recognition Element Functionalized Microfluidic Chip. ACS Sensors. 2022, 7, 2, 666–673.\r
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Siping Liang, Jiaying Li, Zhengyu Zou, Miao Mao, Siqi Ming, Fan Lin, Ziyan Zhang, Can Cao, Jinyu Zhou, Yuanqing Zhang*, Jiaping Li *, Minhao Wu*. Tetrahedral DNA Nanostructures Synergize with MnO2 to Enhance Antitumor Immunity via Promoting STING Activation and M1 Polarization. Acta Pharmaceutica Sinica B. 2022; 12(5), 2494-2505.\r
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Liang Chen, Jie Zhang, Zhun Lin, Ziyan Zhang, Miao Mao, Jiacheng Wu, Qian Li, Yuanqing Zhang*, Chunhai Fan*. Pharmaceutical applications of framework nucleic acids. Acta Pharmaceutica Sinica B. 2022; 12(1), 76-91. Invited Review\r
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Ziyan Zhang, Qiaojuan Liu, Jizhou Tan, Xiaoxia Zhan, Ting Liu, Yuting Wang, Gen Lu*, Minhao Wu*, Yuanqing Zhang*. Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy. Acta Pharmaceutica Sinica B. 2021;11, 1965-1977.(Cover story)\r
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Fan Lin, Yong Shao, Yingjie Wu, Yuanqing Zhang*. NIR light-Propelled Janus-Based Nanoplatform for Cytosolic-Fueled MicroRNA Imaging. ACS Appl. Mater. Interfaces. 2021; 13(3), 3713-3721.\r
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Liang Chen, Siping Liang, Yu Chen, Minhao Wu*, Yuanqing Zhang*. Destructing the Plasma Membrane with Activatable Vesicular DNA Nanopores. ACS Appl. Mater. Interfaces. 2020;12, 1: 96-105.\r
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Jialang Zhuang, Jizhou Tan, Chenglin Wu, Jie Zhang, Ting Liu, Chunhai Fan, Jiaping Li*, Yuanqing Zhang*. Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy. Nucleic Acids Research, 2020, 48(16)，8870-8882.\r
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Yubing Liu, Dabin Chen, Weiqiong Zhang, Yuanqing Zhang*. Mobile DNA tetrahedron on ultra-low adsorption lipid membrane for directional control of cell sensing. Sensors and Actuators B: Chemical. 2020; 307, 127570.\r
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Jialang Zhuang, Jie Zhang, Minhao Wu, Yuanqing Zhang* A Dynamic 3D Tumor Spheroid Chip Enables More Accurate Nanomedicine Uptake Evaluation. Advanced Science. 2019; DOI: 10.1002/advs.201901462\r
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Zhiru Wang, Weiwei Qin*, Jialang Zhuang, Minhao Wu, Qian Li, Chunhai Fan*, Yuanqing Zhang*. Virus-Mimicking Cell Capture Using Heterovalency Magnetic DNA Nanoclaws. ACS Appl. Mater. Interfaces. 2019; 11: 12244–12252.\r
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Maosheng Xu, Kunsong Zhang, Yubing Liu, Jie Wang, Ke Wang*, Yuanqing Zhang*. Multifunctional MoS2 nanosheets with Au NPs grown in situ for synergistic chemo-photothermal therapy. Colloids and Surfaces B: Biointerfaces 2019; 184, 110510.\r
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Ke Wang, Xi Liu, Jialang Zhuang, Yubing Liu, Maosheng Xu, Dong Xie, Junjia Chen*, Xiaoyong Zhang, Yen Wei, Yuanqing Zhang*. Small fluorescent albumin nanoparticles for targeted photothermal therapy via albumin-Binding protein pathways. Colloids and Surfaces B: Biointerfaces 2019; 181,696-704.\r
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Jialang Zhuang, Yongjian Wu, Liang Chen, Siping Liang, Minhao Wu, Ledu Zhou, Chunhai Fan, Yuanqing Zhang*. Single‐Cell Mobility Analysis of Metastatic Breast Cancer Cells. Advanced Science. 2018；DOI: 10.1002/advs.201801158.\r
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Dabin Chen, Duanping Sun, Zhiru Wang, Weiwei Qin, Liang Chen, Ledu Zhou, Yuanqing Zhang*. A DNA nanostructured aptasensor for the sensitive electrochemical detection of HepG2 cells based on multibranched hybridization chain reaction amplification strategy. Biosensors and Bioelectronics. 2018; 117:416-421.\r
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Zijun Zhao, Yu Chen, Ngiambudulu M. Francisco, Yuanqing Zhang*, Minhao Wu*. The application of CAR-T cell therapy in hematological malignancies: Advantages and challenges. Acta Pharmaceutica Sinica B. 2018; 8; 539-551.\r
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Duanping Sun, Jing Lu, Dabin Chen, Yunfei Jiang, Zhiru Wang, Weiwei Qin, Yanyan Yu, Zuanguang Chen, Yuanqing Zhang*. Label-free electrochemical detection of HepG2 tumor cells with a self-assembled DNA nanostructure-based aptasensor. Sensors and Actuators B: Chemical. 2018; 268:359-367.\r
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Yunfei Jiang, Duanping Sun, Zhixian Liang, Liang Chen, Yuanqing Zhang*, Zuanguang Chen*. Label-free and competitive aptamer cytosensor based on layer-by-layer assembly of DNA-platinum nanoparticles for ultrasensitive determination of tumor cells. Sensors and Actuators B: Chemical. 2018; 262:35-43.