个人简历
教育经历 时间 毕业院校 学位 专业 2006-2008 密西根大学医学院 博士 免疫学 2003-2006 俄亥俄州立大学医学院 博士研究生 免疫学 1998-2001 华中农业大学生命科学院 硕士 生化与分子生物学 1994-1998 江西农业大学农学院 学士 农学 工作经历 2014-至今 研究员，中山大学肿瘤防治中心； 2013-2014 Instructor，哈佛大学医学院，癌症免疫学与爱滋病系； 2009-2013 博士后，哈佛大学医学院，癌症免疫学与爱滋病系； 2006-2008 研究助理，密西根大学医学院，普通外科学系； 2003-2006 研究助理，俄亥俄州立大学医学院，病理系； 2001-2003 研发部主管，厦门安普利生物科技有限公司 。
研究领域
肿瘤免疫学和肿瘤免疫治疗”研究
近期论文
1.Penghui Zhou, Donald R. Shaffer, Diana A. Alvarez Arias, Yukoh Nakazaki, Wouter Pos, Alexis J. Torres, Viviana Cremasco, Stephanie K. Dougan, Glenn S. Cowley, Kutlu Elpek, Jennifer Brogdon, John Lamb, Shannon Turley, Hidde L. Ploegh, David E. Root, J. Christopher Love, Glenn Dranoff, Nir Hacohen, Harvey Cantor, Kai W. Wucherpfennig. In vivo Discovery of Immunotherapy Targets in the Tumor Microenvironment. Nature. 506,52–57 (06 February 2014) 2.Penghui Zhou, Kai W. Wucherpfennig. Discovery Cancer Immunotherapy Targets In vivo. Oncoimmunology. 2014 Apr 17;3:e28500. 3.Penghui Zhou, Xianfeng Fang, Ping Yu, Mingzhao Zhu, Yang-Xin Fu, Lizhong Wang, Yang Liu and Pan Zheng. Targeting Lymphotoxin-mediated Negative Selection in the Thymus to Prevent Prostate Cancer in Mice with Genetic Predisposition. Proceedings of the National Academy of Sciences. 2009, 106(40):17134-9. 4.Penghui Zhou, Xincheng Zheng, Huiming Zhang, Yang Liu and Pan Zheng. B7 blockade alters the balance between regulatory T cells and tumor-reactive T cells for immunotherapy of cancer. Clinical Cancer Research. 2009 Feb 1;15(3):960-70. 5.Penghui Zhou, Tan Yifang, He yuqin, Xu Caiguo and Zhang Qifa. Simultaneous Improvement for Four Quality Traits of Zhenshan 97, An Elite Parent of Hybrid rice, by Molecular Marker-assisted Selection. Theoretical and Applied Genetics, 2003 106(2):326-31 6.Lizhong Wang, Runhua Liu, Peiying Ye, Chunshu Wong, Guo-Yun Chen, Penghui Zhou, Kaoru Sakabe, Xincheng Zheng, Wei Wu, Zhang Peng, Taijiao Jiang, Michael Bassetti, Sandro Jube, Yi Sun, Yanping Zhang, Pan Zheng. Intracellular CD24 Disrupts ARF-NPM Interaction and Enables Mutational and Viral Oncogene-mediated p53 Inactivation. Nature Communication, 2015 Jan 20;6:5909. 7.Donald R. Shaffer, Penghui Zhou and Stephen Gottschalk. Foreign or Domestic CARs: Receptor Ligands as Antigen-Binding Domains. Medical Sciences, 2014; 2(1):23-36 8.Diana A. Alvarez Arias, Hye-Jung Kim, Penghui Zhou, Tobias A.W. Holderried, Xuan Wang, Glenn Dranoff and Harvey Cantor. Enhanced murine anti-tumor immunity after genetic disruption of CD8+ regulatory T-cell activity. Cancer Immunology Research, March 2014 2:207-216 9.Lizhong Wang, Runhua Liu, Weiquan Li, Chong Chen, Hiroto Katoh, Guo-Yun Chen, Beth McNally, Lin Lin, Penghui Zhou, Tao Zuo, Kathleen A. Cooney, Yang Liu and Pan Zheng. Somatic Single-hits Inactivate the X-linked Tumor Suppressor FOXP3 in the Prostate. Cancer Cell, 2009 Oct 6;16(4):336-46. 10.Anna I Proietto, Serani van Dommelen, Penghui Zhou, Alex Rizzitelli, Angela D’Amico, Raymond J Steptoe, Shalin H Naik, Mireille H Lahoud, Yang Liu, Pan Zheng, Ken Shortman and Li Wu. Dendritic cells in the thymus contribute to T regulatory cell induction. Proceedings of the National Academy of Sciences. 2008, 105(50): 19619-19874 11.Runhua Liu, Lizhong Wang, Chong Chen, Yan Liu, Penghui Zhou, Yin Wang, Xirui Wang, Julie Turnbull, Berge A. Minassian, Yang Liu, and Pan Zheng. Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms. Molecular and Cellular Biology. 2008 Dec;28(23):7236-44. Epub 2008 Sep 29. 12.Kenneth F. May, Jr., Xing Chang, Huiming Zhang, Kenneth D. Lute, Penghui Zhou, Ergun Kocak, Pan Zheng and Yang Liu. B7-deficient autoreactive T cells are highly susceptible to suppression by CD4(+)CD25(+) regulatory T cells. Journal of Immunology. 2007 Feb 1;178(3):1542-52. 13.Hong Wang, Miaofu Feng, Yaodong Zhou, Penghui Zhou, Weiseng Zeng, Jinghua Cheng and Dan Liu. Clinical and Experimental Study on Lumivudine Resistance by Molecular Beacon. China Biotechnology. 2003, 23(6): 90-93
