个人简历
孙希，女，中山大学中山医学院，副教授，硕士生导师。2011年毕业于中山大学病原生物学专业，获得医学博士学位。2011年留校工作至今。2011年进入中山大学药理学博士后流动站，完成2年师资博士后工作。主要研究方向为寄生虫感染与免疫以及虫源性药物的开发。目前已经作为第一主持人获得“863”青年科学家项目1项，国家自然青年科学基金1项，教育部博士点基金1项，博士后基金1项，广东省自然科学基金1项以及广州市珠江科技新星项目1项；同时作为骨干成员参与国家重点研发项目，“973”项目、“863”项目、国家自然科学基金面上项目、国家自然科学基金-海峡两岸合作项目、国家自然科学基金-NIH项目和广东省自然基金项目多项，并参与国家传染病重大专项研究工作。共发表SCI论文30余篇，其中以第一作者或通讯作者在 Theranostics、J Neuroinflammation、PLoS Negl Trop Dis、Front Microbiol、Front Pharmacol、Oncotarget、Sci Rep、Parasitol Res等杂志发表SCI论文20多篇；申请发明专利3项，其中以第一发明人身份申请国家发明专利并获得授权3项。
研究领域
主要研究方向为寄生虫感染与免疫以及虫源性药物的开发。
近期论文
1）Wan S#, Sun X#, Wu F#, Yu Z, Wang L, Lin D, Li Z, Wu Z*, Sun X*. Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensis. J Neuroinflammation. 2018 Feb 2;15(1):31. doi: 10.1186/s12974-018-1071-2. 2）Zhang B#, Wang L#, Liu J, Xu L, Song L, Wu X, Sun X*, Wu Z*. Case report: A rare case of urinary myiasis induced by the fourth instar larvae of Telmatoscopus albipunctatus. PLoS Negl Trop Dis. 2017 Dec 7;11(12):e0006016. 3）Wu Z#, Wang L#, Tang Y, Sun X*.Parasite-Derived Proteins for the Treatment of Allergies and Autoimmune Diseases. Front Microbiol. 2017 Nov 7;8:2164. 4）Wang L, Yu Z, Wan S, Wu F, Chen W, Zhang B, Lin D, Liu J, Xie H, Sun X*, Wu Z*.Exosomes Derived from Dendritic Cells Treated with Schistosoma japonicum Soluble Egg Antigen Attenuate DSS-Induced Colitis. Front Pharmacol. 2017 Sep 14;8:651. 5）Wang L, Xie H, Xu L, Liao Q, Wan S, Yu Z, Lin D, Zhang B, Lv Z, Wu Z*, Sun X*. rSj16 has protective effect on the severity of DSS- induced colitis by inhibits PPAR-α signaling pathway. Theranostics. 2017 Aug 15;7(14):3446-3460. 6）Liu Z#, Su DM, Yu ZL, Wu F, Liu RF, Luo SQ, Lv ZY, Zeng X, Sun X*, Wu ZD*. Soluble antigens from the neurotropic pathogen Angiostrongylus cantonensis directly inducethymus atrophy in a mouse model. Oncotarget, ,2017,8(30):48575-48590. 7）Sun X#*, Yang F#, Shen J, Liu Z, Liang J, Zheng H, Fung M, Wu Z* .RecombinantParasitol Res. 2016 Dec;115(12):4559-4571. Sj16 from Schistosoma japonicum contains a functional N-terminal nuclear localization signal necessary for nuclear translocation in dendritic cells and interleukin-10 production. 8）Chen AL#, Sun X#, Wang W, Liu JF, Zeng X, Qiu JF, Liu XJ, Wang Y*.Activation of the hypothalamic-pituitary-adrenal (HPA) axis contributes to the immunosuppression of mice infected with Angiostrongylus cantonensis. J Neuroinflammation. 2016 Oct 12;13(1):266. 9）Peng H#, Zhang Q#, Li X, Liu Z, Shen J, Sun R, Wei J, Zhao J, Wu X, Feng F, Zhong S, Sun X*, Wu Z*. IL-33 Contributes to Schistosoma japonicum-induced Hepatic Pathology through Induction of M2 Macrophages. Sci Rep. 2016 Jul 21;6:29844. doi: 10.1038/srep29844. 10）Wu F#, Wei J, Liu Z, Zeng X, Yu Z, Lv, Sun X*, Wu Z*.Soluble antigen derived from IV larva of Angiostrongylus cantonensis promotes chitinase-like protein 3 (Chil3)expression induced by interleukin-13. Parasitol Res. 2016 Oct;115(10):3737-46. Z
