个人简历

 2009年06月获中山大学微生物学博士学位；2009年07月至今，在中山大学人类病毒学研究所从事HIV-1的相关研究，在宿主抗病毒因子与HIV-1相互作用的分子机理、HIV-1储存库形成、维持的分子机理以及艾滋病功能性治愈的免疫重建等方面取得了一系列重要的研究成果。近五年来，共主持国家自然科学基金2项，广东省自然科学基金1项，广东省创新团队子课题1项，高等学校博士点专项基金1项以及中国博士后科学基金1项；参研“十二五”重大传染病专项基金2项。近五年来，在BMC Medicine，J Biol Chem、Virology、PLOS One等期刊发表第一作者/并列通讯作者的SCI学术论文5篇。

研究领域

在中山大学人类病毒学研究所从事HIV-1的相关研究，在宿主抗病毒因子与HIV-1相互作用的分子机理、HIV-1储存库形成、维持的分子机理以及艾滋病功能性治愈的免疫重建等方面取得了一系列重要的研究成果。""

近期论文

1. Liu C, Ma X, Liu B, Chen C, Zhang H*. HIV-1 functional cure: will the dream come true? BMC Medicine. 2015. 13: 284.\r
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2. Huang F, Zhang JS, Zhang YJ, Geng GN, Liang JR, Chen JL, Liu C*, and Zhang H. RNA helicase MOV10 functions as a co-factor of HIV-1 Rev to facilitate Rev/RRE-dependent nuclear export of viral mRNAs. Virology. 2015. 486:15-26.\r
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3. Yin Y, Zhang SY, Luo HH, Zhang X, Geng GN, Li J, Guo XM, Cai WP, Li LH, Liu C*, and Zhang H*. Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance. J Biol Chem. 2015. 290(1):35-45.\r
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4. Zhou X, Luo J, Mills L, Wu S, Pan T, Geng G, Zhang J, Luo H, Liu C*, and Zhang H*. DDX5 facilitates HIV-1 replication as a cellular co-factor of Rev. PLoS ONE. 2013. 8(5): e65040.\r
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5. Liu C*, Zhang X, Huang F, Yang B, Li J, Liu B, Luo H, Zhang P, and Zhang H*. APOBEC3G Inhibits microRNA-mediated repression of translation by interfering with the interaction between argonaute-2 and MOV10. J Biol Chem. 2012. 287: 29373-29383.\r
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6. Li J, Chen C, Ma X, Geng G, Liu B, Zhang Y, Zhang S, Zhong F, Liu C, Yin Y, Cai W, and Zhang H*. Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation. Nat Commun. 2016. 7:11730.\r
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7. Liu B, Zou F, Lu L, Chen C, He D, Zhang X, Tang X, Liu C, Li L, Zhang H*. Chimeric Antigen Receptor T Cells Guided by the Single-Chain Fv of a Broadly Neutralizing Antibody Specifically and Effectively Eradicate Virus Reactivated from Latency in CD4+ T Lymphocytes Isolated from HIV-1-Infected Individuals Receiving Suppressive Combined Antiretroviral Therapy. J Virol. 2016. 90(21):9712-9724.\r
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8. Zhang X, He X, Liu C, Liu J, Hu Q, Pan T, Duan X, Liu B, Zhang Y, Chen J, Ma X, Zhang X, Luo H, and Zhang H*. IL-4 Inhibits the Biogenesis of an Epigenetically Suppressive PIWI-Interacting RNA To Upregulate CD1aMolecules on Monocytes/Dendritic Cells. J Immunol. 2016. 196(4):1591-603.\r
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9. Zhong FD, Zhou N, Wu K, Guo Y, Tan W, Zhang H, Zhang X, Geng GN, Pan T, Luo HH, Zhang YJ, Xu ZB, Liu J, Gao W, Liu C, Ren LL, Li J, Zhou J, and Zhang H*. A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes. Nucleic Acids Res. 2015. 43(21): 10474-91.