个人简历
胡旭初，男，湖南双峰人，1969年出生，硕士生导师。武汉大学病毒学与分子生物学专业学士、军事医学科学院营养与食品卫生学专业硕士，中山大学病原生物学专业博士。主要研究方向为病原生物功能基因组与生物信息学，病原分子生物学和免疫学。目前主要研究领域涉及重要人兽共患寄生虫的功能基因组学、致病机制、病原基因和免疫诊断技术、新型口服疫苗、蠕虫感染的免疫调控和抗肿瘤机制。主持和作为骨干成员参与国家自然科学基金3项、973课题1项、863课题1项、国家科技支撑计划项目1项、教育部博士点基金3 项、省市各类课题6 项。发表论文170多篇，其中第一作者和通讯作者论文23多篇，包括SCI论文12篇。获得专利3项， 作为第一完成人获得教育部“高等学校自然科学二等奖”1 项，作为参与人获得其他省部级奖项3 项。
研究领域
主要研究方向为病原生物功能基因组与生物信息学，病原分子生物学和免疫学。目前主要研究领域涉及重要人兽共患寄生虫的功能基因组学、致病机制、病原基因和免疫诊断技术、新型口服疫苗、蠕虫感染的免疫调控和抗肿瘤机制。
近期论文
1. Zhang Z, Xu H, Gan W, Zeng S, Hu X*. Schistosoma japonicum calcium-binding tegumental protein SjTP22.4 immunization confers praziquantel schistosomulumicide and antifecundity effect in mice. Vaccine. 2012 Jul 20;30(34):5141-50.（通讯作者） 2. Gan W, Zhang Z, Lv G, Xu H, Zeng S, Li Y, Wu W, Hu X*. The topological structure and function of Echinococcus granulosus lactate dehydrogenase, a tegumental transmembrane protein. Mol Biochem Parasitol. 2012 Aug;184(2):109-17. （通讯作者） 3. Li Y, Xu H, Chen J, Gan W, Wu W, Wu W, Hu X*. Gene cloning, expression, and localization of antigen 5 in the life cycle of Echinococcus granulosus .（通讯作者）Parasitol Res. 2012 Jun;110(6):2315-23. 4. Li W, Hu X, Zhang X, Ge Y, Zhao S, Hu Y, Ashman RB. Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice.（并列第一作者） Vaccine. 2011 Jul 26;29(33):5526-33. 5. Li Y, Hu X, Liu X, Huang Y, Xu J, Zhao J, Wu Z, Yu X. Serological diagnosis of clonorchiasis: using a recombinant propeptide of cathepsin L proteinase from Clonorchis sinensis as a candidate antigen.Parasitol Res. Parasitol Res. 2012 Jun;110(6):2315-23. 6. Du L, Tang H, Ma Z, Xu J, Gao W, Chen J, Gan W, Zhang Z, Yu X, Zhou X, Hu X*. The protective effect of the recombinant 53-kDa protein of Trichinella spiralis on experimental colitis in mice.（通讯作者） Dig Dis Sci. 2011 Oct;56(10):2810-7. 7. Wu W, Chen J, Zeng S, Zhang Z, Gan W, Yu X, Hu X*. Molecular cloning, expression, and characterization of cyclophilin A from Clonorchis sinensis.（通讯作者） Parasitol Res. 2011 Aug;109(2):345-51. 8. Chen J, Xu H, Zhang Z, Zeng S, Gan W, Yu X, Hu X*. Cloning and expression of 21.1-kDa tegumental protein of Clonorchis sinensis and human antibody response to it as a trematode-nematode pan-specific serodiagnosis antigen.（通讯作者） Parasitol Res. 2011 Jan;108(1):161-8. 9. Chen J, Hu X, He S, Wang L, Hu D, Wang X, Zheng M, Yang Y, Liang C, Xu J, Yu X. Expression and immune response analysis of Schistosoma japonicum VAL-1, a homologue of vespid venom allergens. Parasitol Res. 2010 May;106(6):1413-8. 10. Gan W, Zhao G, Xu H, Wu W, Du W, Huang J, Yu X, Hu X*. Reverse vaccinology approach identify an Echinococcus granulosus tegumental membrane protein enolase as vaccine candidate.（通讯作者） Parasitol Res. 2010 Mar;106(4):873-82. 11. Li L, Hu X, Wu Z, Xiong S, Zhou Z, Wang X, Xu J, Lu F, Yu X. Immunogenicity of self-adjuvanticity oral vaccine candidate based on use of Bacillus subtilis spore displaying Schistosoma japonicum 26 KDa GST protein. Parasitol Res. 2009 Nov;105(6):1643-51. 12. Yanwen Li , Xuchu Hu, Jing Xu, Fengyu Hu, Changling Ma, Xinbing Yu* Molecular cloning and analysis of stage and tissue-specific expression of Cathepsin L- like protease from Clonorchis sinensis, Parasitol Res ,2009 Aug;105(2):447-52 13. Hu F, Hu X, Ma C, Zhao J, Xu J, Yu X. Molecular characterization of a novel Clonorchis sinensis secretory phospholipase A(2) and investigation of its potential contribution to hepatic fibrosis. Mol Biochem Parasitol. 2009 Oct;167(2):127-34. （并列第一作者） 14. Jiang Huang, Yan Huang , Xuan Wu, Wuying Du,Xinbing Yu, Xuchu Hu*. Identification, expression, characterization and immunolocalization of lactate dehydrogenase from Taenia asiatica , Parasitol Res , 2009 Jan;104(2):287-93. （通讯作者） 15. Xuchu Hu*,Hongjuan Zhou ,Fengyu Hu, Jin Xu ,Yuli Zhao, Xinbing Yu .Recognition and characterization of TGF-β receptor interacting protein 1 (TRIP-1) containing WD40 repeats from Clonorchis sinensis by bioinformatics, cloning, and expression in Escherichia coli ，Parasitol Res, 2008,103:1151-1158 （通讯作者） 16. Hu F, Yu X, Ma C, Zhou H, Zhou Z, Li Y, Lu F, Xu J, Wu Z, Hu X*. Clonorchis sinensis: expression, characterization, immunolocalization and serological reactivity of one excretory/secretory antigen-LPAP homologue, Exp Parasitol. 2007 Oct;117(2):157-64 （通讯作者） 17. Zhou Z, Hu X, Huang Y, Hu H, Ma C, Chen X, Hu F, Xu J, Lu F, Wu Z, Yu X*, Molecular cloning and identification of a novel Clonorchis sinensis gene encoding a tegumental protein.Parasitol Res. 2007 Aug;101(3):737-42 18. Ma C, Hu X, Hu F, Li Y, Chen X, Zhou Z, Lu F, Xu J, Wu Z, Yu X* Molecular characterization and serodiagnosis analysis of a novel lysophospholipase from Clonorchis sinensis, Parasitol Res. 2007 2007 Jul;101(2):419-25. 19. Wu Z, Hu X, Wu D, Xu J, Chen S, Wu Z, Yu X.* Clonorchis sinensis: molecular cloning and functional expression of a novel cytosolic glutathione transferase Parasitol Res. 2007 Jan;100(2):227-32 20. Chen X, Hu X, Wu Z, Yu X, Ma C, Zhou Z Immunological cross-reactivity analysis on recombinant histamine-releasing factors from Schistosoma japonicum, Clonorchis sinensis, and Wistar rat. Parasitol Res 2007 Mar;100(4):749-54.
