个人简历

学习及工作经历： 1999年—2004年：中山大学中山医学院临床医学专业 本科 2004年—2007年：中山大学附属肿瘤医院内科 肿瘤学硕士 2007年—2011年：上海交通大学附属上海胸科医院肺部肿瘤临床医学中心，住院医师 2011年—2017年：中山大学附属肿瘤医院内科，住院医师，主治医师 2013年—2017年：中山大学附属肿瘤医院内科 肿瘤学博士生 2014年—2015年：美国纽约Memorial Sloan Kettering Cancer Center胸部肿瘤内科访问学者 2018年—至今：中山大学附属肿瘤医院内科，副主任医师

研究领域

肿瘤内科治疗（化学治疗、靶向治疗）的临床工作及抗癌药物研究。主要专业方向是胸部肿瘤（肺癌、、胸腺肿瘤、胸膜间皮瘤 ）及鼻咽癌的内科治疗及研究。

近期论文

1.Hou X, Gong R, Zhan J, Zhou T, Ma Y, Zhao Y, Zhang Y, Chen G, Zhang Z, Ma S, Chen X, Gao F, Hong S, Luo F, Fang W, Yang Y, Huang Y, Chen L, Yang H, Zhang L. p300 promotes proliferation, migration,and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells. BMC Cancer. 2018 Jun 7;18(1):641. PMID: 29879950 (IF: 3.29) 2.Hou X, Liang RB, Wei JC, Xu Y, Fu JH, Luo RZ, He JH, Zhang LJ, Lin P, Yang HX. Cyclin D1 expression predicts postoperative distant metastasis and survival in resectable esophageal squamous cell carcinoma. Oncotarget 2016 May 24;7(21):31088-96. PMID: 27145270 (IF: 5.01) 3.Hou X, Wu X, Huang P, Zhan J, Zhou T, Ma Y, Qin T, Luo R, Feng Y, Xu Y, Chen L, Zhang L. Osteopontin is a useful predictor of bone metastasis and survival in patients with locally advanced nasopharyngeal carcinoma. Int J Cancer. 2015 Oct 1; 137(7): 1672-8. PMID: 25824984 (IF: 5.06) 4.Hou X, Wei JC, Fu JH, Wang X, Luo RZ, He JH, Zhang LJ, Lin P, Yang HX. Vascular Endothelial Growth Factor is a Useful Predictor of Postoperative Distant Metastasis and Survival Prognosis in Esophageal Squamous Cell Carcinoma. Ann Surg Oncol. 2015 Oct; 22(11): 3666-73. PMID: 25652047 (IF: 4.16) 5.Hou X, Gu YK, Liu XW, Fu JH, Wang X, Zhang LJ, Luo RZ, Lin P, Yang HX . The Impact of Tumor Cell Differentiation on Survival of Patients with Resectable Esophageal Squamous Cell Carcinomas. Ann Surg Oncol. 2015 Mar; 22(3): 1008-14. PMID: 25201504 (IF:4.16) 6.Hou X, Fu JH, Wang X, Zhang LJ, Liu QW, Luo KJ, Lin P, Yang HX. Prophylactic thoracic duct ligation has unfavorable impact on overall survival in patients with resectable oesophageal cancer. Eur J Surg Oncol. 2014 Dec; 40(12):1756-62. PMID: 24913091 (IF:2.94) 7.Hou X, Wei JC, Fu JH, Wang X, Zhang LJ, Lin P, Yang HX. Proposed Modification of the Seventh American Joint Committee on Cancer Staging System for Esophageal Squamous Cell Carcinoma in Chinese Patients. Ann Surg Oncol. 2014, 21(1):337-42. PMID: 24046121(IF:4.16) 8.Wu X, Liang WH, Hou X (co-first author), Lin Z, Zhao HY, Huang Y, Fang WF, Zhao YY, Wu JX, Yang YP, Xue C, Hu ZH, Zhang J, Zhang JW, Ma YX, Zhou T, Qin T, Zhang L. Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC. OncoTargets and Ther. 2013, 6: 1481-1491. PMID: 24204163 (IF:2.07) 9.Hou X, Wei JC, Wu JX,Wang X, Fu JH, Lin P, Yang HX. Multidisciplinary modalities achieve encouraging long-term survival in resectable limited-disease esophageal small cell carcinoma. PLoS One. 2013 Jul 9; 8(7): e69259. PMID: 23874925 (IF: 4.09) 10.Hou X, Wei JC, Xu Y, Luo RZ, Fu JH, Zhang LJ, Lin P, Yang HX. The positive lymph node ratio predicts long-term survival in patients with operable thoracic esophageal squamous cell carcinoma in China. Ann Surg Oncol. 2013 May; 20(5):1653-9. PMID: 23247981(IF: 4.16) 11.Hou X, Li Y, Luo RZ, Fu JH, He JH, Zhang LJ, Yang HX. High expression of the transcriptional co-activator p300 predicts poor survival in resectable non-small cell lung cancers. Eur J Surg Oncol. 2012; 38(6): 523-30. PMID: 22440742 (IF:2.94) 12.Yang HX, Hou X (co-first author), Liu QW, Zhang LJ, Liu JG, Lin P, Fu JH. Tumor location does not impact long-term survival in patients with operable thoracic esophageal squamous cell carcinoma in China. Ann Thorac Surg. 2012 Jun; 93(6):1861-6. PMID: 22551848 (IF:3.74) 13.Liang Y, Hou X (co-first author), Cui Q, Kang TB, Fu JH, Zhang LJ, Luo RZ, He JH, Zeng YX, Yang HX. Skp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma. J Transl Med. 2012; 10(1):73. doi: 10.1186/1479-5876-10-73.PMID:22533738 (IF:3.47) 14.Hou X, Zhao C, Guo Y, Han F, Lu LX, Wu SX, Li S, Huang PY, Huang H, Zhang L. Different Clinical Significance of Pre- and Post-treatment Plasma Epsteine-Barr Virus DNA Load in Nasopharyngeal Carcinoma Treated with Radiotherapy. Clinical Oncology, 2011, 23(2): 128-33.PMID: 20943358 (IF:2.86) 15.Yang HX, Hou X (co-first author), Lin P, Yang H, Zeng CG, Rong TH, Fu JH. Peripheral direct adjacent lobe invasion non-small cell lung cancer has a similar survival to that of parietal pleural invasion T3 disease. J Thorac Oncol. 2009;4(11):1342-6.PMID: 19861903 (IF:4.47) 16.Yang HX, Hou X (co-first author), Lin P, Rong TH, Yang H, Fu JH. Survival and risk factors of surgically treated mediastinal invasion T4 non-small cell lung cancer. Ann Thorac Surg. 2009;88(2):372-8.PMID: 19632375 (IF:3.74) 17.Yang HX, Hou X (co-first author), Lin P, Rong TH, Yang H, Fu JH.A prognostic analysis of N0-1M0 intralobar metastatic non-small cell lung cancer. Zhonghua Yi Xue Za Zhi. 2009;89:2486-9. Chinese. PMID: 20137436 18.Yang HX, Hou X (co-first author), Lin P, Rong TH, Yang H, Fu JH.Postoperative survival comparison of non-small cell lung cancer between disease with peripheral direct adjacent invasion and resectable T4 disease with mediastinal structures invasion. Zhonghua Yi Xue Za Zhi. 2009;89:1770-3. Chinese. PMID: 19862983 19.Hou X, Zhang L, Zhao C, Li S, Lu LX, Han F, Shao JY, Huang PY. Prognostic impact of plasma Epstein-Barr virus DNA concentration on distant metastasis in Nasopharyngeal Carcinoma. Chinese Journal of Cancer. 2006; 25(7):785-792. Chinese. PMID: 16831265