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丁英
2023-05-18 14:58
  • 丁英
  • 丁英 - 副教授,硕导-中山大学-中山医学院-个人资料

近期热点

资料介绍

个人简历


丁英,副教授,硕士导师。现为中山大学中山医学院组织学与胚胎学教研室教师、党支书。现主要从事电针联合干细胞移植修复脊髓损伤的机制研究。现主要研究方向:督脉电针治疗脊髓损伤抗炎的机制研究;电针通过NT-3介导炎症调节以促进移植的MSC源性神经网络在损伤脊髓内存活及功能性整合的研究。作为主持人已获得国家自然科学基金、教育部高校基本科研业务费、广东省自然科学基金,广东省中医药局科学基金和高校基本科研业务费中山大学青年教师培育计划项目的资助;作为主要合作者参与了广东省科技计划项目和广州市科技计划项目。发表相关SCI论文23篇。

研究领域


现主要从事电针联合干细胞移植修复脊髓损伤的机制研究。现主要研究方向:督脉电针治疗脊髓损伤抗炎的机制研究;电针通过NT-3介导炎症调节以促进移植的MSC源性神经网络在损伤脊髓内存活及功能性整合的研究。

近期论文


1. Al-Ali H, Ding Y(共同第一), Slepak T, Wu W, Sun Y, Martinez Y, Xu XM, Lemmon VP, Bixby JL. The mTOR substrate S6 Kinase 1 (S6K1) is a negative regulator of axon regeneration and a potential drug target for Central Nervous System injury. J Neurosci. 2017 Jul 26;37(30):7079-7095. 2. Zhang YT, Jin H, Wang JH, Wen LY, Yang Y, Ruan JW, Zhang SX, Ling EA, Ding Y*, Zeng YS*. Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats. Neural Plast. 2017:7351238. 3. Yang XH, Ding Y(共同第一), Li W, Zhang RY, Wu JL, Ling EA, Wu W, Zeng YS*. Effects of electroacupuncture and the retinoid X receptor (RXR) signalling pathway on oligodendrocyte differentiation in the demyelinated spinal cord of rats. Acupunct Med. 2017, 35(2):122-1324. 4. Ding Y, Zhang RY, He B, Liu Z, Zhang K, Ruan JW, Ling EA, Wu JL, Zeng YS. Combination of Electroacupuncture and Grafted Mesenchymal Stem Cells Overexpressing TrkC Improves Remyelination and Function in Demyelinated Spinal Cord of Rats. Scientific Reports 2015, Published 16 March, DOI: 10.1038/srep09133 5. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zeng X, Huang SF, Zhang YJ, Wu JL, Fisher D, Dong H, Zeng YS. Electroacupuncture promotes the differentiation of transplanted bone marrow mesenchymal stem cells over expressing TrkC into neuron-like cells in transected spinal cord of rats. Cell Transplant, 2013, 22(1):65-86. 6. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zeng X, Huang SF, Zhang YJ, Wang S, Dong H, Zeng YS. Bone marrow mesenchymal stem cells and electro-acupuncture downregulate the inhibitor molecules and promote the axonal regeneration in the transected spinal cord of rats. Cell Transplant, 2011, 20(4):475-491. 7. Ma YH, Zeng X, Qiu XC, Wei QS, Che MT, Ding Y, Liu Z, Wu GH, Sun JH, Pang M, Rong LM, Liu B, Aljuboori Z, Han I, Ling EA, Zeng YS. Perineurium-like sheath derived from long-term surviving mesenchymal stem cells confers nerve protection to the injured spinal cord.Biomaterials. 2018 Apr;160:37-55. 8. Li G, Che MT, Zhang K, Qin LN, Zhang YT, Chen RQ, Rong LM, Liu S, Ding Y, Shen HY, Long SM, Wu JL, Ling EA, Zeng YS. Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury.Biomaterials. 2016 Mar;83:233-48. 9. Qiu XC, Jin H, Zhang RY, Ding Y, Zeng X, Lai BQ, Ling EA, Wu JL, Zeng YS. Donor mesenchymal stem cell-derived neural-like cells transdifferentiate into myelin-forming cells and promote axon regeneration in rat spinal cord transection.Stem Cell Res Ther. 2015,27;6:105.

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