个人简历

曾昭蕾，医学博士，副研究员，博士生导师，入选“广东特支计划”科技创新青年拔尖人才。主要从事胃肠道肿瘤转化医学研究。目前主持国家重点研发计划课题、国家自然科学基金面上项目等多项国家级基金项目，作为主要研究人员参与国家高技术研究发展计划（863计划）、广东省自然科学基金重点项目，广州市协同创新重大专项等多项科研项目研究。作为主要完成人获得中华医学科技奖三等奖。 （一）教育背景和留学经历： 2005-2009 中山大学，获医学博士学位 2014-2015 The University of Texas MD Anderson Cancer Center, 公派留学访问学者

研究领域

胃肠道肿瘤转化医学研究

近期论文

1: Chen DL, Wang ZQ, Zeng ZL#, Wu WJ, Zhang DS, Luo HY, Wang F, Qiu MZ, Wang DS, Ren C, Wang FH, Chiao LJ, Pelicano H, Huang P, Li YH, Xu RH*. Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression. Hepatology. 2014 Aug;60(2):598-609. (IF=13.246) 2: Zeng ZL, Luo HY, Yang J, Wu WJ, Chen DL, Huang P, Xu RH*. Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer. Clin Cancer Res. 2014 Feb 15;20(4):1042-52. (IF=9.619) 3: Zeng ZL, Lin HX, Zhao X, Liu G, Wang X, Xu R, Chen K, Li J, Song L*. Overexpression of GOLPH3 promotes proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Clin Cancer Res. 2012 Aug 1;18(15):4059-69. (IF=9.619) 4: Chen DL#, Zeng ZL#, Yang J, Ren C, Wang DS, Wu WJ, Xu RH*. L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer. J Hematol Oncol. 2013 Jun 27; 6:43. (IF=6.350) 5: Wu WJ#, Zhang Y#, Zeng ZL #, Li XB, Hu KS, Luo HY, Yang J, Huang P, Xu RH*. β-phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype. Biochem Pharmacol. 2013 Feb 15;85(4):486-96. (IF=4.581) 6: Zeng ZL, Wu WJ, Yang J, Tang ZJ, Chen DL, Qiu MZ, Luo HY, Wang ZQ, Jin Y, Wang DS, Xu RH*. Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma. J Transl Med. 2012 Aug 31; 10:181. (IF=3.786) 7: Zhao H#, Zeng ZL#, Yang J, Jin Y, Qiu MZ, Hu XY, Han J, Liu KY, Liao JW, Xu RH, Zou QF*. Prognostic relevance of Period1 (Per1) and Period2 (Per2) expression in human gastric cancer. Int J Clin Exp Pathol. 2014 Jan 15;7(2):619-30. (IF=1.706) 8: Zeng ZL, Wu MW, Sun J, Sun YL, Cai YC, Huang YJ, Xian LJ*. Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity. J Biochem. 2010 Sep;148(3):319-26. (IF=2.082)