王强
近期热点
资料介绍
个人简历
学习经历:2000-2004,武汉大学药学院,药学专业,医学学士2004-2009,山东大学药学院,药物化学专业,医学博士2014-2015,佐治亚州立大学,化学系,访问学者工作经历:2010-2013,中南民族大学,药学系,讲师2013-至今,中南民族大学,药学系,副教授研究领域
小分子药物的设计与合成近期论文
[1]Q.Wang,Q.Shi,L.Huang,NovelAminopeptidaseNInhibitorswithImprovedAntitumorActivities,LettDrugDesDiscov,13(2016)98-106.[2]L.Zhang,Y.Han,Q.Jiang,C.Wang,X.Chen,X.Li,F.Xu,Y.Jiang,Q.Wang,W.Xu,Trendofhistonedeacetylaseinhibitorsincancertherapy:isoformselectivityormultitargetedstrategy,Medicinalresearchreviews,35(2015)63-84.[3]X.Song,Z.Zhao,X.Qi,S.Tang,Q.Wang,T.Zhu,Q.Gu,M.Liu,J.Li,IdentificationofepipolythiodioxopiperazinesHDN-1andchaetocinasnovelinhibitorofheatshockprotein90,Oncotarget,6(2015)5263-5274.[4]L.Shuai,Z.Chen,P.Fei,Q.Wang,T.Yang,Spectroscopicanalysisontheinteractionofferulicacidandtetramethylpyrazinewithtrypsin,Luminescence:thejournalofbiologicalandchemicalluminescence,29(2014)79-86.[5]H.Gao,W.Guo,Q.Wang,L.Zhang,M.Zhu,T.Zhu,Q.Gu,W.Wang,D.Li,Aspulvinonesfromamangroverhizospheresoil-derivedfungusAspergillusterreusGwq-48withanti-influenzaAviral(H1N1)activity,Bioorganic&medicinalchemistryletters,23(2013)1776-1778.[6]J.Zhang,X.Pan,C.Wang,F.Wang,P.Li,W.Xu,L.He,Pharmacophoremodeling,3D-QSARstudies,andin-silicoADMEpredictionofpyrrolidinederivativesasneuraminidaseinhibitors,Chemicalbiology&drugdesign,79(2012)353-359.[7]Q.Li,H.Fang,X.Wang,G.Hu,Q.Wang,W.Xu,Novelpotent2,5-pyrrolidinedionepeptidomimeticsasaminopeptidaseNinhibitors.Design,synthesisandactivityevaluation,Bioorganic&medicinalchemistryletters,22(2012)850-853.[8]L.Zhang,H.Zhu,Q.Wang,H.Fang,W.Xu,M.Li,Homologymodeling,moleculardynamicsimulationanddockingstudiesofcyclindependentkinase1,Journalofmolecularmodeling,17(2011)219-226.[9]J.Su,Q.Wang,J.Feng,C.Zhang,D.Zhu,T.Wei,W.Xu,L.Gu,EngineeredThermoplasmaacidophilumfactorF3mimicshumanaminopeptidaseN(APN)asatargetforanticancerdrugdevelopment,Bioorganic&medicinalchemistry,19(2011)2991-2996.[10]Y.Luan,Q.Wang,N.Liu,J.Mou,X.Jiao,H.Fang,M.Li,W.Xu,SynthesisandactivityevaluationofanewbestatinderivativeLYP2asanaminopeptidaseNinhibitor,Anti-cancerdrugs,22(2011)99-103.[11]J.Mou,H.Fang,Y.Liu,L.Shang,Q.Wang,L.Zhang,W.Xu,Design,synthesisandprimaryactivityassayofbi-ortri-peptideanalogueswiththescaffoldl-arginineasamino-peptidaseN/CD13inhibitors,Bioorganic&medicinalchemistry,18(2010)887-895.[12]K.Yang,Q.Wang,L.Su,H.Fang,X.Wang,J.Gong,B.Wang,W.Xu,DesignandsynthesisofnovelchloramphenicolaminederivativesaspotentaminopeptidaseN(APN/CD13)inhibitors,Bioorganic&medicinalchemistry,17(2009)3810-3817.[13]L.Shang,H.Fang,H.Zhu,X.Wang,Q.Wang,J.Mu,B.Wang,S.Kishioka,W.Xu,Design,synthesisandSARstudiesoftripeptideanalogswiththescaffold3-phenylpropane-1,2-diamineasaminopeptidaseN/CD13inhibitors,Bioorganic&medicinalchemistry,17(2009)2775-2784.[14]J.Mou,H.Fang,F.Jing,Q.Wang,Y.Liu,H.Zhu,L.Shang,X.Wang,W.Xu,Design,synthesisandprimaryactivityevaluationofL-argininederivativesasamino-peptidaseN/CD13inhibitors,Bioorganic&medicinalchemistry,17(2009)4666-4673.[15]Y.Liu,L.Shang,H.Fang,H.Zhu,J.Mu,Q.Wang,X.Wang,Y.Yuan,W.Xu,Design,synthesis,andpreliminarystudiesoftheactivityofnovelderivativesofN-cinnamoyl-L-asparticacidasinhibitorsofaminopeptidaseN/CD13,Bioorganic&medicinalchemistry,17(2009)7398-7404.[16]X.Li,Y.Wang,J.Wu,Y.Li,Q.Wang,W.Xu,NovelaminopeptidaseNinhibitorsderivedfromantineoplastonAS2-5(PartII),Bioorganic&medicinalchemistry,17(2009)3061-3071.[17]J.Zhang,Q.Wang,H.Fang,W.Xu,A.Liu,G.Du,Design,synthesis,inhibitoryactivity,andSARstudiesofhydrophobicp-aminosalicylicacidderivativesasneuraminidaseinhibitors,Bioorganic&medicinalchemistry,16(2008)3839-3847.[18]Q.Wang,M.Chen,H.Zhu,J.Zhang,H.Fang,B.Wang,W.Xu,Design,synthesis,andQSARstudiesofnovellysinederivesasamino-peptidaseN/CD13inhibitors,Bioorganic&medicinalchemistry,16(2008)5473-5481.[19]L.Shang,Q.Wang,H.Fang,J.Mu,X.Wang,Y.Yuan,B.Wang,W.Xu,Novel3-phenylpropane-1,2-diaminederivatesasinhibitorsofaminopeptidaseN(APN),Bioorganic&medicinalchemistry,16(2008)9984-9990.[20]J.Zhang,Q.Wang,H.Fang,W.Xu,A.Liu,G.Du,Design,synthesis,inhibitoryactivity,andSARstudiesofpyrrolidinederivativesasneuraminidaseinhibitors,Bioorganic&medicinalchemistry,15(2007)2749-2758.[21]L.Zhang,J.Zhang,H.Fang,Q.Wang,W.Xu,Design,synthesisandpreliminaryevaluationofnewcinnamoylpyrrolidinederivativesaspotentgelatinaseinhibitors,Bioorganic&medicinalchemistry,14(2006)8286-8294. 相关热点
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