个人简历

钱兆生，博士，副教授，硕士生导师，浙江省杰出青年基金获得者，分析学科主任。2009.6月南京大学化学化工学院化学专业获理学博士学位，博士论文曾获2011年度全国优秀博士学位论文提名论文。2009.8起在浙江师范大学分析化学学科开展分析化学教学工作和相关科研工作。2013-2014年由国家公派到美国华盛顿大学做访问研究一年。目前从事于纳米材料的光致发光性能及其传感应用研究和基于小分子有机化合物的分子开关的设计与合成。目前主持一项国家自然科学基金面上项目和浙江省杰出青年基金，主持完成国家自然科学基金青年基金和一项浙江省自然科学基金，参与两项国家自然科学基金面上项目和一项浙江省自然科学基金，主持完成一项横向项目；已在JACS、ChemComm、Anal. Chem.、Biosens. Bioelectron.、Chem. Eur. J.、Nanoscale、J. Mater. Chem.、SNB、ACS Applied Mater. Interface等国际著名学术期刊上发表六十余篇论文; 高被引论文有3篇，总引用次数超过1300次，被邀为JACS、Anal. Chem.、Biosens. Bioelectron.、SNB、Nanoscale、ACA、Talanta、Carbon等刊物的审稿人。目前指导研究生七名，已毕业研究生六名，指导研究生曾获研究生国家奖学金、耿儿奖学金、学校科学创新一等奖和二等奖、浙江省优秀研究生学位论文培育基金、校级优秀研究生学位论文培育基金等。

研究领域

"""""1. 新型发光纳米材料的合成和性质研究，包括碳量子点、金银铜纳米簇及无机量子点等；基于新型纳米荧光材料，设计与构建可逆的发光纳米开关，用于磷酸酶、糖苷酶等水解酶活性定量检测方法的建立\r
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2. 基于有机小分子化合物的分子开关的设计、合成及分析检测应用，着重研究基于聚集诱导发光体系的磷光分子开关的设计与构建，并将其用于酪氨酸酶、硝基还原酶等氧化还原酶活性定量检测方法的建立，探索小分子光学探针在细胞和生物体内实时荧光示踪功能"

近期论文

Hui Feng, Zhaosheng Qian*. Functional Carbon Quantum Dots: A Versatile Platform for Chemosensing and Biosensing.Chem. Rec., 2018, DOI: 10.10002/tcr/201700055. (Invited Review)\r
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Guilin Chen, Hui Feng, Xiaogan Jiang, Jing Xu, Saifei Pan, Zhaosheng Qian*. Redox-controlled fluorescent nanoswitch based on reversible disulfide and its application in butyrylcholinesterase activity assay.Anal.Chem., 2018, 90, 1643-1651.\r
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Jing Xu, Fengqi Zhou, Luxi Chen, Guilin Chen, Saifei Pan, Zhaosheng Qian, Hui Feng.* Thiol-triggered disaggregation-induced emission controlled by competitive coordination for acetylcholinesterase monitoring and inhibitor screening. Sens. Actuat. B-Chem, 2018, 255, 22-28.\r
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Meizhi Zhao, Hui Feng, Xiaoxiao Zhang, Hang Ao, Zhaosheng Qian*. Bonding-Induced Emission of Silyl-Protected Copper Nanoclusters for Luminescence Turn-on Detection of Trace Water in Organic Solvents.Analyst, 2017, 142, 4613-4617. (Cover Paper)\r
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Hang Ao, Hui Feng, Mengting Zhao, Meizhi Zhao, Jianrong Chen, Zhaosheng Qian.* Redox-triggered bonding-induced emission of thiol-functionalized gold nanoclusters for luminescence turn-on detection of molecular oxygen. ACS Sens., 2017, 2, 1692-1699.\r
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Meizhi Zhao, Zhaosheng Qian(Coauthors), Mengting Zhong, Zhentian Chen, Hang Ao, Hui Feng.* Fabrication of stable and luminescent copper nanocluster-based AIE particles and their application in β-galactosidase activity assay. ACS Appl. Mater. Interfaces, 2017, 9, 32887-32895.\r
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Meizhi Zhao, Hui Feng, Jiaonan Han, Hang Ao, Zhaosheng Qian*. Multi-stimuli responsive copper nanoclusters with bright red luminescence for quantifying acid phosphatase via redox-controlled luminescence switch. Anal Chim. Acta, 2017, 984, 202-210.\r
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Yuanyuan Huang, Hui Feng, Weidong Liu, Shasha Zhang, Cong Tang, Jianrong Chen, Zhaosheng Qian,* Cation-driven luminescent self-assembled dots of copper nanoclusters with aggregation-induced emission for beta-galactosidase activity monitoring, J. Mater. Chem. B, 2017, 5, 5120-5127.\r
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Cong Tang, Hui Feng, Yuanyuan Huang, Zhaosheng Qian*. Reversible Luminescent Nanoswitches Based on Aggregation-Induced Emission Enhancement of Silver nanoclusters for Luminescence Turn-on Assay of Inorganic Pyrophosphatase Activity. Anal. Chem. 2017, 89, 4994-5002. \r
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Qian Sun, Siying Fang, Yafen Fang, Zhaosheng Qian, Hui Feng*. Fluorometric Detection of Cholestrol Based on beta-Cyclodextrin Functionalized Carbon Quantum Dots via Competitive Host-Guest Recognition.Talanta, 2017,167, 513-519.\r
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Ao Hang, Hui Feng, Xiaolu Huang, Meizhi Zhao, Zhaosheng Qian*. A Reversible Fluorescence Nanoswitch Based on Dynamic Covalent B-O Bonds Using Functional Carbon Quantum Dots and Its Application for α-Glucosidase Activity Monitoring. J. Mater. Chem. C, 2017, 5, 2826-2832.\r
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Cong Tang, Jin Zhou, Zhaosheng Qian(Co-first author), Yanyan Ma, Yuanyuan Huang, Hui Feng*. A Universal Fluorometric Assay Strategy for Glycosidases Based on Functional Carbon Quantum Dots: ß-Galactosidase Activity Detection in vitro and in Living Cells. J. Mater. Chem. B, 2017, 5, 1971-1979.\r
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Cong Tang, Zhaosheng Qian(Co-first author), Yinjie Qian, Yuanyuan Huang, Meizhi Zhao, Hang Ao, Hui Feng*. A Fluorometric and Real-time Assay for α-Glucosidase Activity Through Supramolecular Self-assembly and Its Application for Inhibitor Screening. Sens. Actuat. B-Chem, 2017, 245, 282-289.\r
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Hong Huang, Hua Li, Jiuju Feng, Hui Feng, Aijun Wang,* Zhaosheng Qian.* One-pot green synthesis of highly fluorescent glutathione-stabilized copper nanoclusters for Fe3+ sensing. Sens. Actuat. B Chem. 2017, 241, 292-297.\r
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Aijun Wang, Hua Li, Hong Huang, Zhaosheng Qian, Jiuju Feng*. Fluorescent graphene-like carbon nitrides: synthesis, properties and applications, J. Mater. Chem. C, 2016, 4, 8146-8160.\r
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Yuanyuan Huang, Hui Feng, Weidong Liu, Yingying Zhou, Cong Tang, Hang Ao, Meizhi Zhao, Guilin Chen, Jianrong Chen, Zhaosheng Qian*. Luminescent aggregated copper nanoclusters nanoswitch controlled by hydrophobic interaction for real-time monitoring of acid phosphatatse activity. Anal. Chem., 2016, 88, 11575-11583.\r
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Fengqi Zhou, Hui Feng, Yafen Fang, Qian Sun, Zhaosheng Qian*. Phenylsulfonic acid functionalized carbon quantum dots based on biosensor for acetylcholinesterase activity monitoring and inhibitor screening. RSC Adv., 2016, 6, 105454-105460.\r
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Yuanyuan Huang, Jin Zhou, Hui Feng, Jieyu Zheng, Hui-Min Ma, Weidong Liu, Cong Tang, Hang Ao, Meizhi Zhao, Zhaosheng Qian*. A dual-channel fluorescent chemosensor for discriminative detection of glutathione based on functionalized carbon quantum dots. Biosens. Bioelectron., 2016, 86, 748-755.\r
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Hang Ao, Zhaosheng Qian (Co-first author), Yuyu Zhu, Meizhi Zhao, Cong Tang, Yuanyuan Huang, Hui Feng,* Aijun Wang. A fluorometric biosensor based on functional Au/Ag nanoclusters for real-time monitoring of tyrosinase activity. Biosens. Bioelectron., 2016, 83, 542-547.\r
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Cong Tang, Zhaosheng Qian, Yuanyuan Huang, Jiamin Xu, Hang Ao, Meizhi Zhao, Jin Zhou, Jianrong Chen, Hui Feng.* A fluorometric assay for alkaline phosphatase activity based on beta-cyclodextrin-modified carbon quantum dots through host-guest recognition. Biosens. Bioelectron., 2016, 83, 274-280.