陈士国
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陈士国,教授,博导,副系主任,教育部青年长江学者,获国家自然科学基金(青年、面上)、国家重点研发计划、浙江省重点研发项目等10多项省部级项目资助;在RG-I型果胶提取及应用技术、海参靶向抗凝寡糖开发、杨梅叶原花色素等新型食品原料开发等领域取得创新性成果,获教育部自然科学一等奖(2/6)、教育部科技进步一等奖(2/12)等奖励及国际食品功能因子大会(ICOFF)青年科学家、首届香江学者荣誉。第一及通讯作者发表SCI论文77篇,H指数36,主要发表在JAFC,Food Chemistry,Food Hydrocolloids,Carbohydrate polymers等食品及亲水胶体领域的一区期刊上。第一发明人授权国家发明专利15件,申请国际专利5件(3件美国专利)。专利成果共以第一申请人申请发明专利19项,其中授权12项:1.陈士国;郭欣;叶兴乾;薛长湖。可溶性鱿鱼墨黑色素的制备方法及其用途。(ZL.201110326181.3,2013.08.07)2.陈士国,尹馨梓,刘东红,胡亚芹,陈建初,孙玉敬,吴丹,叶兴乾。果胶磺化的方法.(ZL201210012638.8,2014.3.5)3.陈士国,叶兴乾,薛长湖,李国云,廖宁波.菲律宾刺参硫酸软骨素多糖及其提取方法和用途(ZL 201110347315X,2014.03.05授权)4.陈士国,薛长湖,李国云,董平.美国肉参岩藻糖基化粘多糖及其用途.(ZL 2011104601757,2014.07.02授权)5、陈士国,吴念,刘东红,胡亚芹,陈健初,孙玉敬,吴丹,叶兴乾.海参多糖的电离辐射降解法.(申请号,201210007582.7,2012年1月3日申请,2015年1月23日授权)6、陈士国;陈健乐;程焕;叶兴乾;胡亚芹;李俊慧;吴丹;支梓鉴。一种回收柑橘罐头碱处理水中果胶的方法。(申请号,CN201610367574.1,2016年5月27日申请,授权)7、陈士国;陈健乐;程焕;叶兴乾;陈健初;丁甜;李俊慧;胡亚芹。一种柑橘罐头加工酸处理水中聚半乳糖醛酸的纯化方法。(申请号,CN201610367408.1,2016年5月27日申请,授权)8、陈士国;李珊;李俊慧;支梓鉴;叶兴乾;胡亚芹。一种海洋硫酸多糖的快速纯化方法。(申请号,CN201610224470.5,申请日,2016-04-12,授权)9、陈士国;李昕;叶兴乾;刘东红;陈健初;胡亚琴;丁甜。一种富含异黄酮的葛根熟全粉的制备方法。(CN201510903600.3)10、陈士国;李珊;李俊慧;叶兴乾;胡亚芹。一种不合格奶的标记方法以及原料乳的鉴定方法。(申请号,CN201510703116.6,申请日,2015-10-23,授权)11、陈士国;潘俊贤;叶兴乾;陈健初;胡亚芹;刘东红;丁甜。杨梅叶原花色素在油脂抗氧化中的应用。(申请号CN201510141887.0,申请日,2015年-03-30)12、陈士国,郭欣,叶兴乾,孙玉敬,刘东红.低分子量海参岩藻聚糖硫酸酯的制备方法.(201310052587.6,2015年8月10日授权)13、陈士国,张华,陈健乐,叶兴乾,刘东红。柑橘果胶在慢融化冰激凌制备中的应用。14、陈士国,支梓鉴,陈健乐,丁甜,刘东红,叶兴乾。一种富含RG-I结构的低分子量果胶制备方法。CN201710097564.515、陈士国,支梓鉴,叶兴乾.一种低分子量肝素的制备方法。CN201710121658.1,16、陈士国;李俊慧;李珊;叶兴乾;胡亚芹;刘东红;丁甜.一种低分子量果胶的制备方法,CN201710344597.5,申请日,2017-8-25申请PCT专利PCT专利:17、陈士国、严鲁峰,叶兴乾。一种海参硫酸软骨素寡糖及其快速制备方法,PCT/CN2018/095211:18、陈士国,郑家琪,张华,叶兴乾,刘东红。PCT/CN2018/107919一种柑橘源复合益生元制剂的制备方法与应用:19、陈士国,张华,叶兴乾,刘东红。一种提取富含RG-I果胶的方法PCT/CN2017/103412。教学与课程食品专业英语水产品利用化学食品功能碳水化合物(研究生)食品科学进展(博士生)食品工艺学综合实验(求是科学班)现代食品科学技术硕博及博士后招收硕博研究生:本实验室欢迎食品科学、分析化学、合成化学及分子生物学、高分子及超分子等背景的学生联系,其中博士研究生招生要求以第一(或者)导师第一作者在主流期刊上发表SCI论文;博士后:本实验室欢迎食品科学、分析化学、合成化学及分子生物学、高分子及超分子等背景的博士毕业生联系(年龄35岁以下),要求在国际相关领域主流期刊上发表1篇以上论文;待遇年薪参考浙江大学博士后待遇(15-20万),同时课题组根据工作表现给予一定的补贴,支持联系申请香江学者,博创计划等博士后人才项目。工作研究项目近年来,先后获得国家自然科学基金(青年,面上),国家重点研发计划(子课题),宁夏自治区重点研发计划、浙江省公益性项目、中国博士后一等及特别资助、香江学者计划等10多项国家级省部级项目的支持;奖励荣誉获得首届香江学者,教育部自然科学一等奖、浙江省科技进步三等奖、全国商量联合会二等奖等奖项实验室介绍本实验室依托“食品加工工程创新团队”,国家“万人计划”创新领军人才等国家级、151重点等人才7人次,近年来承担国家重点研发计划、863计划、国家自然科学基金等国家和省部级重大项目共计40余项;荣获国家科技进步(科普)二等奖、教育部高等自然奖一等奖、浙江省科技进步一等奖等重要奖项14项,累计发表SCI论文300多篇,拥有专利成果50余项获国家奖学金4人次、聚光奖学金等各类奖项近20人次,校优秀毕业生、校三好研究生等荣誉近60人次;欢迎各类优秀人才加盟!研究领域
1)新型替代靶向FXase抗凝、抗血栓低聚海参岩藻糖糖基化硫酸软骨素构效机制及产品开发;2)新型高RG-I果胶的制备、精细结构与功能及低聚物功能能产品(从柑橘加工废弃物中回收人参型果胶);3)马铃薯、柑橘等大宗果蔬资源废弃皮、渣及加工水中可持续加工技术(节水技术、营养功效因子回收及产业化);4)常绿林叶资源中原花色素资源的精细结构及基于抗氧化、降血脂等机制的功能产品开发;(以南方杨梅等常绿林业资源为代表)""近期论文
2020年1.Fucosylated chondroitin sulfate 9-18 oligomers exhibit molecular size-independent antithrombotic activity during circulating in the blood.Yan,Lufeng;Wang,Danli;Yu,Yanlei;Zhang,Fuming;Ye,Xingqian;Linhardt,Robert*;Chen,Shiguo*.ACS Chemical biology,2020,In press.2.Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced Obesity.Author(s):Zhu,Kai;Mao,Guizhu;Wu,Dongmei;Yu,Chengxiao;Xiao,Hang;Ye,Xingqian;Linhardt,Robert;Orfila,Caroline;Chen,Shiguo*.Journal of Agricultural and Food Chemistry,2020,in press.(Cover Page)3.Assembly of Oil-Based Microcapsules Coated with Proanthocyanidins as a Novel Carrier for Hydrophobic Active Compounds.H Pan,X Shen,W Tao,S Chen*,X Ye*.Journal of Agricultural and Food Chemistry,2020,in press.(Cover Page)4.H Pan,X Shen,W tao,S Chen*,X Ye*,Fabrication of polydopamine-based curcumin nanoparticles for chemical stability and pH-responsive delivery,Journal of Agricultural and Food Chemistry,in press.5.Antioxidant and pancreatic lipase inhibitory effects of flavonoids from different citrus peel extracts:an in vitro study.R Huang,Y Zhang,S Shen,Z Zhi,H Chen,S Chen*,X Ye*.Food Chemistry,2020,in press.6.S Chen*,X Shen,W Tao,G Mao,W Wu,S Zhou,X Ye,H Pan*.Preparation of a novel emulsifier by self-assembling of proanthocyanidins from Chinese bayberry(Myrica rubra Sieb.et Zucc.)leaves with gelatin,Food Chemistry,126570.7.Extraction temperature is a decisive factor for the properties of pectin.Jianle Chen,Huan Cheng,Zijian Zhi,Hua Zhang,Robert Linhardt,Fuming Zhang,Shiguo chen*and Xingqian Ye*,food hydrocolloids,in press.8.Oral administration of fucosylated chondroitin sulfate oligomers in gastro-resistant microcapsules exhibits a safe antithrombotic activity.L.Yan,M.Zhu,D.Wang,W.Tao,D.Liu,F.Zhang,R.J.Linhardt,X.Ye*,S.Chen*.Thrombosis and Haemostasis,in press,2020.9.Structure-activity Relationship of Citrus Segment Membrane RG-I Pectin against Galectin-3:The Galactan is Not the Only Important Factor.D Wu,J Zheng,W Hu,X Zheng,Q He,RJ Linhardt,X Ye,S Chen*.Carbohydrate Polymers,2020,in press.10.Z Zhang,J Tian*,H Fang,H Zhang,X Kong,D Wu,J Zheng,D Liu,X Ye,S.Chen*,Physicochemical and Digestion Properties of Potato Starch Were Modified by Complexing with Grape Seed Proanthocyanidins,Molecules 25(5),1123.11.S Zhou,A Rahman,J Li,C Wei,J Chen,RJ Linhardt,X Ye*,S Chen*.Extraction Methods Affect the Structure of Goji(Lycium barbarum)Polysaccharides,Molecules 25(4),936.2019年论文1.Guizhu Mao,Shan Li,Xuemin Shen,Shengyi Zhou,Caroline Orfila,Robert J.Linhardt,X.Ye,Shiguo Chen*:Depolymerized RG-I enriched pectin from citrus segment membrane modulates gut microbiota,increases SCFAs production,promotes the growth of Bifidobacterium spp.,Lactobacillus spp.and Faecalibaculum spp..Food&Function 10/2019;,DOI:10.1039/C9FO01534E2.Dongmei Wu,Jiaqi Zheng,Guizhu Mao,Weiwei Hu,Xingqian Ye,Robert J.Linhardt,Shiguo Chen*:Rethinking the impact of RG-I mainly from fruits and vegetables on dietary health.Critical Reviews in Food Science and Nutrition 10/2019;,DOI:10.1080/10408398.2019.16720373.Honglin Chen,Hua Zhang,Jinhu Tian,John Shi,Robert J.Linhardt,Tian Ding Xingqian Ye*,Shiguo Chen*:Recovery of High Value‐Added Nutrients from Fruit and Vegetable Industrial Wastewater.Comprehensive Reviews in Food Science and Food Safety 08/2019;18(5).,DOI:10.1111/1541-4337.124774.Lufeng Yan,Lingyun Li,Junhui Li,Yanlei Yu,Xinyue Liu,Xingqian Ye,Robert J Linhardt,Shiguo Chen*:Bottom-up analysis using liquid chromatography-Fourier transform mass spectrometry to characterize fucosylated chondroitin sulfates from sea cucumbers.Glycobiology 07/2019;,DOI:10.1093/glycob/cwz0575.Wenyang Tao,Yu Zhang,Xuemin Shen,Yanping Cao,John Shi,Xingqian Ye,Shiguo Chen*:Rethinking the Mechanism of the Health Benefits of Proanthocyanidins:Absorption,Metabolism,and Interaction with Gut Microbiota.Comprehensive Reviews in Food Science and Food Safety 06/2019;,DOI:10.1111/1541-4337.124446.Lufeng Yan,Danli Wang,Mengshan Zhu,Yanlei Yu,Fuming Zhang,Xingqian Ye,Robert J.Linhardt*,Shiguo Chen*:Highly purified fucosylated chondroitin sulfate oligomers with selective intrinsic factor Xase complex inhibition.Carbohydrate Polymers 06/2019;222:115025.,DOI:10.1016/j.carbpol.2019.1150257.Xuemin Shen,Zhenfeng Liu,Junhui Li,Dongmei Wu,Meng Zhu,Lufeng Yan,Guizhu Mao,Xingqian Ye,Robert J.Linhardt,Shiguo Chen*:Development of low molecular weight heparin by H2O2/ascorbic acid with ultrasonic power and its anti-metastasis property.International Journal of Biological Macromolecules 04/2019;133.,DOI:10.1016/j.ijbiomac.2019.04.0198.Shan Li,Junhui Li,Guizhu Mao,Lufeng Yan,Yaqin Hu,Xingqian Ye,Ding Tian,Robert J.Linhardt,Shiguo Chen*:Effect of the sulfation pattern of sea cucumber-derived fucoidan oligosaccharides on modulating metabolic syndromes and gut microbiota dysbiosis caused by HFD in mice.Journal of Functional Foods 04/2019;55:193-210.,DOI:10.1016/j.jff.2019.02.0019.Gelling mechanism of RG-I enriched citrus pectin:Role of arabinose side-chains in cation-and acid-induced gelation.J Zheng,J Chen,H Zhang,D Wu,X Ye,RJ Linardt,S Chen*.Food Hydrocolloids 101,10553610.Reconsidering conventional and innovative methods for pectin extraction from fruit and vegetable waste:Targeting rhamnogalacturonan I.G Mao,D Wu,C Wei,W Tao,X Ye,RJ Linhardt,C Orfila,S Chen*,Trends in Food Science&Technology,in press.2018年论文1.Junhui Li,Shan Li,Limei Wu,Huifang Yang,Chaoyang Wei,Tian Ding,Robert J.Linhardt,Xiaoliang Zheng,Xingqian Ye,Shiguo Chen*:Ultrasound-assisted fast preparation of low molecular weight fucosylated chondroitin sulfate with antitumor activity.Carbohydrate Polymers 12/2018;209.,DOI:10.1016/j.carbpol.2018.12.0612.Zijian Zhi,Jianle Chen,Shan Li,Junhui Li,Xingqian Ye,Huan Cheng,Robert J.Linhardt,Shiguo Chen*:Preparation of low molecular weight heparin using ultrasound-assisted Fenton-system.Ultrasonics Sonochemistry 11/2018;52.,DOI:10.1016/j.ultsonch.2018.11.0163.Shan Li,Junhui Li,Guizhu Mao,Tiantian Wu,Dingbo Lin,Yaqin Hu,Xingqian Ye,Ding Tian,Wengang Chai,Robert J.Linhardt,Shiguo Chen:Fucosylated chondroitin sulfate from Isostichopus badionotus alleviates metabolic syndromes and gut microbiota dysbiosis induced by high-fat and high-fructose diet.International Journal of Biological Macromolecules 11/2018;124.,DOI:10.1016/j.ijbiomac.2018.11.1674.Junhui Li,Shan Li,Shanshan Liu,Chaoyang Wei,Lufeng Yan,Tian Ding,Robert J.Linhardt,Donghong Liu,Xingqian Ye,Shiguo Chen:Pectic oligosaccharides hydrolyzed from citrus canning processing water by Fenton reaction and their antiproliferation potentials.International Journal of Biological Macromolecules 11/2018;124.,DOI:10.1016/j.ijbiomac.2018.11.1665.Shan Li,Junhui Li,Guizhu Mao,Tiantian Wu,Yaqin Hu,Xingqian Ye,Tian Ding,Robert J.Linhardt,Shiguo Chen:A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice.Food&Function 09/2018;9(10).,DOI:10.1039/C8FO01174E6.Chaoyang Wei,Yu Zhang,Liang He,Junwen Cheng,Junhui Li,Wenyang Tao,Guizhu Mao,Hua Zhang,Robert J.Linhardt,Xingqian Ye,Shiguo Chen:Structural characterization and anti-proliferative activities of partially degraded polysaccharides from peach gum.Carbohydrate Polymers 09/2018;203.,DOI:10.1016/j.carbpol.2018.09.0297.Shan Li,Junhui Li,Guizhu Mao,Yaqin Hu,Xingqian Ye,Ding Tian,Robert J.Linhardt,Shiguo Chen:Fucosylated chondroitin sulfate oligosaccharides from Isostichopus badionotus regulates lipid disorder in C57BL/6 mice fed a high-fat diet.Carbohydrate Polymers 08/2018;201.,DOI:10.1016/j.carbpol.2018.08.0208.Shuyu Shen,Rui Huang,Charlie Li,Wenyan Wu,Honglin Chen,John Shi,Shiguo Chen,Xingqian Ye:Phenolic Compositions and Antioxidant Activities Differ Significantly among Sorghum Grains with Different Applications.Molecules 05/2018;23(5):1203.,DOI:10.3390/molecules230512039.Rui Huang,Wenyan Wu,Shuyu Shen,Jiawen Fan,Yue Chang,Shiguo Chen,X.Ye:Evaluation of colorimetric methods for quantification of citrus flavonoids to avoid misuse.Analytical methods 05/2018;10(22).,DOI:10.1039/C8AY00661J10.Junhui Li,Shan Li,Yangfan Zheng,Hua Zhang,Jianle Chen,Lufeng Yan,Tian Ding,Robert J.Linhardt,Caroline Orfila,Donghong Liu,Xingqian Ye,Shiguo Chen:Fast preparation of rhamnogalacturonan I enriched low molecular weight pectic polysaccharide by ultrasonically accelerated metal-free Fenton reaction.Food Hydrocolloids 05/2018;,DOI:10.1016/j.foodhyd.2018.05.02511.Hua Zhang,Jianle Chen,Junhui Li,Chaoyang Wei,Xingqian Ye,John Shi,Shiguo Chen:Pectin from Citrus Canning Wastewater as Potential Fat Replacer in Ice Cream.Molecules 04/2018;23(4):925.,DOI:10.3390/molecules2304092512.Chaoyang Wei,Yu Zhang,Hua Zhang,Junhui Li,Wenyang Tao,Robert J.Linhardt,Shiguo Chen,Xingqian Ye:Physicochemical properties and conformations of water-soluble peach gums via different preparation methods.Food Hydrocolloids 03/2018;95.,DOI:10.1016/j.foodhyd.2018.03.04913.Lanqi Li,Yu Zhang,Binggui Sun,Heng Zhang,Wenyang Tao,Jinhu Tian,Xingqian Ye,Shiguo Chen:The neuroprotective effects of Chinese bayberry leaves proanthocyanidins.Journal of Functional Foods 01/2018;40:554-563.,DOI:10.1016/j.jff.2017.08.0312017年1.Lufeng Yan,Xingqian Ye,Robert J.Linhardt,Jianle Chen,Dandan Yu,Rui Huang,Dong Hong Liu,Shiguo Chen:Full recovery of value-added compounds from citrus canning processing water.Journal of Cleaner Production 12/2017;176.,DOI:10.1016/j.jclepro.2017.12.0182.Hua Zhang,Jianle Chen,Junhui Li,Lufeng Yan,Shan Li,Xingqian Ye,Donghong Liu,Tian Ding,Robert J.Linhardt,Caroline Orfila,Shiguo Chen:Extraction and characterization of RG-I enriched pectic polysaccharides from mandarin citrus peel.Food Hydrocolloids 12/2017;79.,DOI:10.1016/j.foodhyd.2017.12.0023.Zijian Zhi,Jianle Chen,Shan Li,Wenjun Wang,Rui Huang,Donghong Liu,Tian Ding,Robert John Linhardt,Shiguo Chen,Xingqian Ye:Fast preparation of RG-I enriched ultra-low molecular weight pectin by an ultrasound accelerated Fenton process.Scientific Reports 12/2017;7(1).,DOI:10.1038/s41598-017-00572-34.Isaac Agyekum,Lauren Pepi,Yanlei Yu,Junhui Li,Lufeng Yan,Robert J Linhardt,Shiguo Chen,I Jonathan Amster:Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS.European Journal of Mass Spectrometry 09/2017;24(1).,DOI:10.1177/14690667177319005.Lufeng Yan,Junhui Li,Danli Wang,Ding Tian,Yaqin Hu,Xingqian Ye,Robert J.Linhardt,Shiguo Chen:Molecular size is important for the safety and selective inhibition of intrinsic factor Xase for fucosylated chondroitin sulfate.Carbohydrate Polymers 09/2017;178.,DOI:10.1016/j.carbpol.2017.09.0346.Yaqin Hu,Ying Shao,Chunhua Wu,Chunhong Yuan,Gakushi Ishimura,Wenjuan Liu,Shiguo Chen:γ-PGA and MTGase improve the formation ofε-(γ-glutamyl)lysine cross-links within hairtail(Trichiurus haumela)surimi protein.Food Chemistry 08/2017;242.,DOI:10.1016/j.foodchem.2017.08.0877.Junhui Li,Shan Li,Lufeng Yan,Tian Ding,Robert J.Linhardt,Yanlei Yu,Xinyue Liu,Donghong Liu,Xingqian Ye,Shiguo Chen:Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation:Importance of sulfation pattern and molecular size.European Journal of Medicinal Chemistry 07/2017;139.,DOI:10.1016/j.ejmech.2017.07.0658.Shan Li,Junhui Li,Zijian Zhi,Chaoyang Wei,Wenjun Wang,Tian Ding,Xingqian Ye,Yaqin Hu,Robert J.Linhardt,Shiguo Chen:Macromolecular properties and hypolipidemic effects of four sulfated polysaccharides from sea cucumbers.Carbohydrate Polymers 05/2017;173.,DOI:10.1016/j.carbpol.2017.05.0639.Chao-Yang Wei,Ning-Bo Liao,Yu Zhang,Xing-Qian Ye,Shan Li,Ya-Qin Hu,Dong-Hong Liu,Robert J.Linhardt,Xin Wang,Shi-Guo Chen:In vitro fermentation behaviors of fucosylated chondroitin sulfate from Pearsonothuria graeffei by human gut microflora.International journal of biological macromolecules 04/2017;102.,DOI:10.1016/j.ijbiomac.2017.04.03610.Shan Li,Junhui Li,Zijian Zhi,Yaqin Hu,Jian Ge,Xingqian Ye,Ding Tian,Linhardt Robert,Shiguo Chen:4-O-Sulfation in sea cucumber fucodians contribute to reversing dyslipidiaemia caused by HFD.International journal of biological macromolecules 02/2017;99.,DOI:10.1016/j.ijbiomac.2017.01.14511.Yaqin Hu,Tiantian Wu,Chunhua Wu,Shalu Fu,Chunhong Yuan,Shiguo Chen:Formation and optimization of chitosan-nisin microcapsules and its characterization for antibacterial activity.Food Control 02/2017;72:43-52.,DOI:10.1016/j.foodcont2016.06.01320161.Yu Zhang,Xiaozhou Zhou,Wenyang Tao,Lanqi Li,Chaoyang Wei,Jie Duan,Shiguo Chen,Xingqian Ye:Antioxidant and antiproliferative activities of proanthocyanidins from Chinese bayberry(Myrica rubra Sieb.et Zucc.)leaves.Journal of Functional Foods 12/2016;27.,DOI:10.1016/j.jff.2016.10.0042.Jianle Chen,Huan Cheng,Dan Wu,Robert J.Linhardt,Zijian Zhi,Lufeng Yan,Shiguo Chen,Xingqian Ye:Green recovery of pectic polysaccharides from citrus canning processing water.Journal of Cleaner Production 12/2016;144.,DOI:10.1016/j.jclepro.2016.12.1403.Jun-hui Li,Shan Li,Zi-jian Zhi,Lu-feng Yan,Xing-qian Ye,Tian Ding,Lei Yan,Robert John Linhardt,Shi-guo Chen:Depolymerization of Fucosylated Chondroitin Sulfate with a Modified Fenton-System and Anticoagulant Activity of the Resulting Fragments.Marine Drugs 09/2016;14(9):170.,DOI:10.3390/md140901704.Yaqin Hu,Tiantian Wu,Chunhua Wu,Shalu Fu,Chunhong Yuan,Shiguo Chen:Formation and optimization of chitosan-nisin microcapsules and its characterization for antibacterial activity.Food Control 07/2016;72.,DOI:10.1016/j.foodcont.2016.06.0135.Nian Wu,Yu Zhang,Xingqian Ye,Yaqin Hu,Tian Ding,Shiguo Chen:Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate.Carbohydrate Polymers 03/2016;147.,DOI:10.1016/j.carbpol.2016.03.0136.Jinhu Tian,Jianchu Chen,Xingqian Ye,Shiguo Chen:Health benefits of the potato affected by domestic cooking:A review.Food Chemistry 01/2016;202.,DOI:10.1016/j.foodchem.2016.01.12020151.Jinhu Tian,Jianle Chen,Feiyan Lv,Shiguo Chen,Jianchu Chen,Donghong Liu,Xingqian Ye:Domestic cooking methods affect the phytochemical composition and antioxidant activity of purple-fleshed potatoes.Food Chemistry 11/2015;197(Pt B).,DOI:10.1016/j.foodchem.2015.11.0492.Yaqin Hu,Shan Li,Junhui Li,Xingqian Ye,Tian Ding,Donghong Liu,Jianchu Chen,Zhiwei Ge,Shiguo Chen:Identification of a highly sulfated fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated tetrasaccharides units.Carbohydrate Polymers 07/2015;134.,DOI:10.1016/j.carbpol.2015.06.0883.Yaqin Hu,Wenjuan Liu,Chunhong Yuan,Katsuji Morioka,Shiguo Chen,Donghong Liu,Xingqian Ye:Enhancement of the gelation properties of hairtail(Trichiurus haumela)muscle protein with curdlan and transglutaminase.Food Chemistry 06/2015;176.,DOI:10.1016/j.foodchem.2014.12.0064.Yaqin Hu,Xingqian Ye,Xinzi Yin,Shiguo Chen:Sulfation of citrus pectin by pyridine-sulfurtrioxide complex and its anticoagulant activity.LWT-Food Science and Technology 03/2015;60(2):1162-1167.,DOI:10.1016/j.lwt.2014.09.01820141.Ruichang Gao,Nian Wu,Yuan Li,Shiguo Chen:Structures and Anticoagulant Activities of the Partially Mild Acidic Hydrolysis Products of the Fucosylated Chondroitin Sulfate from Sea Cucumber Pearsonothuria graeffei.Journal of Carbohydrate Chemistry 11/2014;33(9).,DOI:10.1080/07328303.2014.9657802.Nian Wu,Shiguo Chen,Xingqian Ye,Guoyun Li,Li’ang Yin,Changhu Xue:Identification of Fucans from Four Species of Sea Cucumber by High Temperature 1H NMR.Journal of Ocean University of China 10/2014;13(5).,DOI:10.1007/s11802-014-2287-03.Yaqin Hu,Hiaxia Yu,Kaicheng Dong,Shuibing Yang,Xingqian Ye,Shiguo Chen:Analysis of the tenderisation of jumbo squid(Dosidicus gigas)meat by ultrasonic treatment using response surface methodology.Food Chemistry 10/2014;160:219–225.,DOI:10.1016/j.foodchem.2014.01.0854.Shi-Guo Chen,Xin Guo,Xingqian Ye,Yujing Sun,Dan Wu,Nian Wu,Yaqin Hu:Ultrasound Effects on the Degradation Kinetics,Structure,and Antioxidant Activity of Sea Cucumber Fucoidan.Journal of Agricultural and Food Chemistry 01/2014;62(5).,DOI:10.1021/jf404717y5.Ningbo Liao,Shiguo Chen,Xingqian Ye,Xuan Ye,Jianjun Zhong,Xinzi Yin,Donghong Liu:Structural Characterization of a Novel Glucan from Achatina fulica and Its Antioxidant Activity.Journal of Agricultural and Food Chemistry 01/2014;62(11).,DOI:10.1021/jf403896c6.Fu-Rong Wang,Zhong-Guo Xie,Xing-Qian Ye,Shang-Gui Deng,Ya-Qin Hu,Xin Guo,Shi-Guo Chen:Effectiveness of treatment of iron deficiency anemia in rats with squid ink melanin–Fe.12/2013;5(1).,DOI:10.1039/c3fo60383k20131.Xin Guo,Shiguo Chen,Yaqin Hu,Guoyun Li,Ningbo Liao,Xingqian Ye,Donghong Liu,Changhu Xue:Preparation of water-soluble melanin from squid ink using ultrasound-assisted degradation and its anti-oxidant activity.Journal of Food Science and Technology-Mysore-12/2013;51(12).,DOI:10.1007/s13197-013-0937-72.Donghong Liu,Ningbo Liao,Xingqian Ye,Yaqin Hu,Dan Wu,Xin Guo,Jianjun Zhong,Jianyong Wu,Shiguo Chen:Isolation and Structural Characterization of a Novel Antioxidant Mannoglucan from a Marine Bubble Snail,Bullacta exarata(Philippi).Marine Drugs 11/2013;11(11):4464-4477.,DOI:10.3390/md111144643.Shiguo Chen,Ka-Chai Siu,Wen-Qiang Wang,Xing-Xun Liu,Jian-Yong Wu:Structure and antioxidant activity of a novel poly-N-Acetylhexosamine produced by a medicinal fungus.04/2013;94(1):332-8.,DOI:10.1016/j.carbpol.2012.12.0674.Nian Wu,Xingqian Ye,Xin Guo,Ningbo Liao,Xinzi Yin,Yaqin Hu,Yujing Sun,Donghong Liu,Shiguo Chen:Depolymerization of fucosylated chondroitin sulfate from sea cucumber,Pearsonothuria graeffei,via Co-60 irradiation.04/2013;93(2):604-14.,DOI:10.1016/j.carbpol.2012.12.0445.Ningbo Liao,Shiguo Chen,Xingqian Ye,Jianjun Zhong,Nian Wu,Shilei Dong,Bo Yang,Donghong Liu:Antioxidant and anti-tumor activity of a polysaccharide from freshwater clam,Corbicula fluminea.01/2013;4(4).,DOI:10.1039/c2fo30178d6.Shiguo Chen,Guoyun Li,Nian Wu,Xin Guo,Ningbo Liao,Xingqian Ye,Donghong Liu,Changhu Xue,Wengang Chai:Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates.Biochimica et Biophysica Acta 01/2013;1830(4).,DOI:10.1016/j.bbagen.2013.01.0017.Xin Guo,Shiguo Chen,Changhu Xue,Yaqin Hu,Donghong Liu,Xingqian Ye:Ultrasound-assisted degradation for preparing soluble melanin from squid ink and its anti-oxidant activity.01/2013;37(7):1113.,DOI:10.3724/SP.J.1231.2013.385662007-2012年1.Shiguo Chen,Yaqin Hu,Xinqian Ye,Guoyun Li,Guangli Yu,Changhu Xue,Wengang Chai:Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus.Biochimica et Biophysica Acta 03/2012;1820(7):989-1000.,DOI:10.1016/j.bbagen.2012.03.0022.Guoyun Li,Shiguo Chen,Yuming Wang,Yong Xue,Yaoguang Chang,Zhaojie Li,Jingfeng Wang,Changhu Xue:A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannai Ino:Purification,structure identification and anticoagulant activity.International journal of biological macromolecules 09/2011;49(5):1160-6.,DOI:10.1016/j.ijbiomac.2011.09.0173.Shiguo Chen,Changhu Xue,Li’ang Yin,Qingjuan Tang,Guangli Yu,Wengang Chai:Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers.Carbohydrate Polymers 01/2011;83(2-83):688-696.,DOI:10.1016/j.carbpol.2010.08.0404.S.-G.Chen,Z.-J.Li,Y.-M.Wang,G.-Y.Li,B.-B.Sun,C.-H.Xue:Sulfation of a Squid ink polysaccharide and its anticoagulant activities[J].Chemical Journal of Chinese Universities-Chinese Edition-12/2010;12(12).5.Shiguo Chen,Jingfeng Wang,Changhu Xue,Hui Li,Beibei Sun,Yong Xue,Wengang Chai:Sulfation of a squid ink polysaccharide and its inhibitory effect on tumor cell metastasis.Carbohydrate Polymers 07/2010;81(3):560-566.,DOI:10.1016/j.carbpol.2010.03.0096.S.G.Chen,G.Y.Li,L.A.Yin,W.C.Huang,P.Dong,J.Xu,Y.G.Chang,C.H.Xue:Identification of eight species of sea cucumber chondroitin sulfates by high temperature 1H NMR.7.Shiguo Chen,Changhu Xue,Jingfeng Wang,Hui Feng,Yuming Wang,Qin Ma,Dongfeng Wang:Adsorption of Pb(II)and Cd(II)by Squid Ommastrephes bartrami Melanin.Bioinorganic Chemistry and Applications 12/2009;2009(1):901563.,DOI:10.1155/2009/9015638.Shiguo Chen,Jie Xu,Changhu Xue,Ping Dong,Wenjing Sheng,Guangli Yu,Wengang Chai:Sequence determination of a non-sulfated glycosaminoglycan-like polysaccharide from melanin-free ink of the squid Ommastrephes bartrami by negative-ion electrospray tandem mass spectrometry and NMR spectroscopy.Glycoconjugate Journal 08/2008;25(5):481-92.,DOI:10.1007/s10719-007-9096-2Food Science and Nutrition 副主编,Foood reviews international, Process等国际期刊编委。标签: 浙江大学 生物系统工程与食品科学学院
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