杨勇
近期热点
资料介绍
个人简历
杨勇,男,1976年12月生,中国药科大学基础医学与临床药学学院院长,新药安全评价研究中心主任,教授、博士生导师,入选国家“创新人才推进计划中青年科技创新领军人才”和国家“百千万工程国家级人才”,被授予“有突出贡献中青年专家”称号,享受国务院政府特殊津贴。目前已在国际重要学术期刊如PNAS、Gut、Hepatology、Cancer Research等发表SCI论文50余篇,其中第一作者或通讯作者40余篇,SCI期刊累计他引超过3000次,单篇论文最高他引250次;申请发明专利8项,其中已授权5项。累计承担20余项新药临床前研究,获得临床批件或备案多项。先后主持国家自然科学基金“重大研究计划”,主持科技部“十二五重大新药创制专项”和“十三五重大新药创制专项”和首届江苏省杰出青年基金。2016年获得“上海市科技进步一等奖”,2015年荣获“中国药理学会施维雅青年药理学家奖”。研究领域
肿瘤免疫治疗和新药创制""近期论文
1.Zhang WB, Wang Z, Su F, Jin YH, Liu HY, Wang QJ, Yang Y*. Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition. J Biol Chem.(Corresponding author) 2010, 285, 52: 40461–40471.2. Qing-yi Zhu, Zhuo Wang, Chao Ji, Yan-li Yang, Yong-hua Jin, Qiu-juan Wang, Zhi-gang Bi, Gang, Hu, Yong Yang*. C6-Ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT de-phosphorylation and α-tubulin hyper-acetylation both in vitro and in vivo. Cell Death & Disease. (2011) 2, e117; doi:10.1038/cddis.2010.96. (Corresponding author)3.Hai-xia Ji, Yu-lian Zou, Jing-jing Duan, Zhi-rong Jia, Xian-jing Li, Zhuo Wang, Li Li, Yongwen Li, Gen-yan Liu, Ming-Qing Tong, Xiao-yi Li, Guo-hui Zhang, Xiang-rong Dai, Ling He, Zhiyu Li, Cong Cao, Yong Yang*. The Synthetic Melanocortin (CKPV)2 Exerts Anti-Fungal and Anti-Inflammatory Effects against Candida albicans Vaginitis via Inducing Macrophage M2 Polarization. PLoS ONE. 2013,8(2): e56004. (Corresponding author)4.Chen Fei-Hong; Zhang Lin-Bo; Qiang Lei; Yang Zhen; Wu Tian; Zou Mei-Juan; Tao Lei; You Qi-Dong; Li Zhi-Yu; Yang Yong*; Guo Qing-Long. Reactive oxygen species-mitochondria pathway involved in LY-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.Cancer letters. (Corresponding author) 2010;296(1):96-105.5.Yong Yang, Xian-jing Li, Zhen Chen, Xuan-xuan Zhu, Jing Wang, Lin-bo Zhang, Qiang Lei, Yan-jun Ma, Zhi-yu Li, Qing-long Guo, Qi-dong You. Wogonin induced calreticulin/Annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. PLoS ONE. 2012,7(12):e50811. 相关热点
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