个人简历

陆涛：教授，药物化学专业博士生导师，江苏省教学名师，中国药科大学副校长。现担任全国药学专业学位研究生教育指导委员会副主任委员；中国药品监督研究会药品监管人才培养专业委员会主任委员；中国药学会科技评价工作委员会副主任委员；国家基金委生命科学部通讯评议专家，教育部本科教学审核评估专家；江苏省学位委员会委员；江苏化学化工学会理事、有机化学专业委员会委员等学术职务。《药学进展》执行主编，《中国药科大学学报》编委。

研究领域

""新药分子设计与合成研究、计算机辅助药物设计、有机合成化学、药物生物统计与计算药学""""

近期论文

Yanmin Zhang, Yadong Chen, Danfeng Zhang, Lu Wang, Tao Lu,* and Yu Jiao*. Discovery of Novel Potent VEGFR-2 Inhibitors Exerting Significant Antiproliferative Activity against Cancer Cell Lines. J. Med. Chem.2018, 61, 140-157 \r
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Yue Wang,Yanle Zhi,Qiaomei Jin,Shuai Lu,Guowu Lin, Haoliang Yuan,Taotao Yang,Zhanwei Wang,Chao Yao,Jun Ling,Hao Guo,Tonghui Li,Jianlin Jin,Baoquan Li,Li Zhang,Yadong Chen*,and Tao Lu*. Discovery of 4‑((7H‑Pyrrolo[2,3‑d]pyrimidin-4-yl)amino)‑N‑(4-((4-methylpiperazin-1-yl)methyl)phenyl)‑1H‑pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia. J. Med. Chem. 2018, 61, 1499-1518\r
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Li Zhang, Jingyun Zhao, Beichen Zhang, Tao Lu*, Yadong Chen*. Discovery of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as novel, potent and selective c-Met kinase inhibitors: Synthesis, SAR study, and biological activity. Eur. J. Med. Chem. 2018, 150, 809–816\r
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Lu Wang, Yanmin Zhang, Qing Zhang, Gaoyuan Zhu, Zhimin Zhang, Chunqi Duan, Tao Lu*, Weifang Tang*. Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance. Eur. J. Med. Chem. 2019, 163, 243–255.\r
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Qi Y. Wang, Hong M. Li, Zhi P. Dong, Bing X. Li, Ming Huo, Tao Lu* and Yue Wang*. Peptide-mediated cationic micelles drug-delivery system applied on a VEGFR3-overexpressed tumor. J. Mater. Chem. B, 2019, 7, 1076–1086.\r
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Shuaishuai Fang, Shiyi Jin, Rui Ma, Tao Lu*, Ding Du*. Asymmetric Synthesis of C2-Quaternary Indolin-3-ones Enabled by N-Heterocyclic Carbene Catalysis. Org. Lett. 2019, 21, 5211-5214. \r
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Yin Long，Xing Junhao，Wang Yuhan，ShenYue，Lu Tao*，Hayashi Tamio*，Dou Xiaowei*. Enantioselective Synthesis of 3,3'-Diaryl-SPINOLs: Rhodium-Catalyzed Asymmetric Arylation/BF3 -Promoted Spirocyclization Sequence. Angew Chem Int Ed Engl. 2019, 58(8), 2474-2478.\r
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Fei Jiang,Qinghua Hu,Zhimin Zhang,Hongmei Li,Huili Li,Dewei Zhang,Hanwen Li, Yu Ma,Jingjing Xu,Haifang Chen,Yong Cui,Yanle Zhi, Yanmin Zhang,† Junyu Xu, Jiapeng Zhu*,Tao Lu*,and Yadong Chen*. Discovery of Benzo[cd]indol-2(1H)‑ones and Pyrrolo[4,3,2-de]quinolin-2(1H)‑ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis. J. Med. Chem.2019, 62, 11080−11107\r
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Wang Qi Y，Li, Hong M， Dong, ZP，Li, Bing X，Huo, Ming，Lu, Tao*，Wang Yue*. Peptide-mediated cationic micelles drug-delivery system applied on a VEGFR3-overexpressed tumor. J Mater Chem B. 2019, 7(7), 1076-1086. \r
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Hong-Mei Li, Yan-Ran Bi, Yang Li, Rong Fu, Wen-Cong Lv, Nan Jiang, Ying Xu,Bo-Xue Ren, Ya-Dong Chen, Hui Xie, Shui Wang, Tao Lu*, Zhao-Qiu Wu*. A potent CBP/p300-Snail interaction inhibitorsuppresses tumor growth and metastasis inwild-type p53-expressing cancer. Sci. Adv. 2020; 6 : eaaw8500